Evaluating silver nanoparticles, copper coatings, and zinc oxide nanostructures for antimicrobial medical device applications DOI Creative Commons
Priyeshkumar Thangavel Anandapillai,

Samudram Manickam Kamali,

V. Malathy

et al.

Matéria (Rio de Janeiro), Journal Year: 2024, Volume and Issue: 29(4)

Published: Jan. 1, 2024

ABSTRACT The increase in hospital-acquired infections (HAIs) associated with medical devices underscores the need for antimicrobial coatings. This study aims to compare efficacy, biocompatibility, ion release, and durability of silver nanoparticles, copper coatings, zinc oxide nanostructures as coatings devices. Coatings were prepared characterized, efficacy tested against E. coli S. aureus via inhibition zone measurements. Silver demonstrated highest effect, zones averaging 90%, while showed moderate 80% 70%, respectively. Biocompatibility, assessed using human fibroblasts an MTT assay, cell viability oxide, followed by silver. Durability tests under simulated physiological conditions indicated that retained over 90% structural integrity, greater degradation. Ion release profiles highlighted silver’s rapid ideal short-term activity, steady, sustained release. These findings suggest immediate infection control, offer balanced long-term safety durability, making them suitable extended applications

Language: Английский

Precise surface engineering: Leveraging chemical vapor deposition for enhanced biocompatibility and durability in biomedical implants DOI Creative Commons

Tasfia Saba,

Khondoker Safin Kaosar Saad,

Adib Bin Rashid

et al.

Heliyon, Journal Year: 2024, Volume and Issue: 10(18), P. e37976 - e37976

Published: Sept. 1, 2024

Language: Английский

Citations

8

Prospects and challenges of thin film coating materials and their applications DOI
Md. Ibrahim Abdullah,

Md Mubashir Hosain,

Md Mahadi Hassan Parvez

et al.

Inorganic Chemistry Communications, Journal Year: 2025, Volume and Issue: unknown, P. 114117 - 114117

Published: Feb. 1, 2025

Language: Английский

Citations

0

Advancements in Surface Coatings for Enhancing Longevity in Hip Implants: A Review DOI Open Access
Nishant Nikam, B. Satish Shenoy,

K N Chethan

et al.

Prosthesis, Journal Year: 2025, Volume and Issue: 7(1), P. 21 - 21

Published: Feb. 18, 2025

Background/Objectives: The increasing demand for total hip arthroplasty (THA), due to aging populations and active lifestyles, necessitates advancements in implant materials design. This review evaluates the role of surface coatings enhancing performance, biocompatibility, longevity implants. It addresses challenges like wear, corrosion, infection, focusing on innovative engineering solutions. Methods: analyzes various modification techniques, including physical vapor deposition (PVD), chemical (CVD), electrophoretic (EPD), plasma spraying, ion implantation. also examines their effectiveness improving tribological properties, resistance infection. Computational methods such as finite element analysis (FEA) are discussed predicting potential coating failures. Results: findings underscore posed by wear debris corrosion common configurations, metal-on-metal (MoM) metal-on-polyethylene (MoP). Innovative coatings, diamond-like carbon (DLC) films hydroxyapatite (HA) layers, demonstrate enhanced performance reducing friction, bacterial adhesion, while promoting osteogenic cell attachment. Surface textures optimized properties further improve functionality. Multifunctional exhibit balancing biocompatibility infection resistance. Conclusions: plays a critical advancing next-generation integration advanced modifications enhances durability, reduces complications, improves patient outcomes. Future research should focus combining computational modeling refine strategies long-term success THA.

Language: Английский

Citations

0

Biological Coatings: Advanced Strategies Driving Multifunctionality and Clinical Potential in Dermal Substitutes DOI Open Access

Yanshuang Wu,

Chao Ji, Zhenzhen Yan

et al.

Journal of Biomedical Materials Research Part B Applied Biomaterials, Journal Year: 2025, Volume and Issue: 113(3)

Published: Feb. 24, 2025

ABSTRACT Skin tissue defects caused by various acute and chronic etiologies frequently occur in clinical medicine. Traditional surgical repair methods have certain limitations, while dermal substitutes combined with skin grafting become an alternative to conventional surgery. Biological coatings, loading bioactive substances such as polysaccharides proteins, or using carriers, can promote cell adhesion, proliferation, differentiation. This optimizes the mechanical properties biocompatibility of substitutes, enhances their antibacterial properties, improves feasibility for application. paper explores common biological coating materials construction used field substitutes. It highlights importance necessity coatings development multifunctional designs By summarizing current research, this aims offer new insights references design application

Language: Английский

Citations

0

Advances in Dental Implants: A Review of In Vitro and In Vivo Testing with Nanoparticle Coatings DOI Open Access

Ana Maria Gianina Rehner,

Elena-Theodora Moldoveanu,

Adelina-Gabriela Niculescu

et al.

Journal of Composites Science, Journal Year: 2025, Volume and Issue: 9(3), P. 140 - 140

Published: March 17, 2025

Since tooth loss is a common problem in humans and widespread worldwide, dental implants are an effective optimal alternative to solve this problem. Thus, it necessary develop with improved surfaces that favor the osseointegration of implant into surrounding tissues promote cell adhesion proliferation while also preventing inhibiting peri-implant infections can lead failure. In regard, review aims provide new insights nanotechnology use nanoparticles creating coatings, trends for enhancing surfaces, current technologies used purpose. Although vitro vivo tests attest possible nanomaterials described review, further needed establish concentrations be safe clinical trials.

Language: Английский

Citations

0

Mechanical and Wear Resistance of TiCN Coatings on NiTi Substrate DOI

Nasim Botshekanan,

Hudsa Majidian, M. Ghanbariha

et al.

Tribology Transactions, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 14

Published: March 24, 2025

Titanium carbonitride (TiCN) is well-known as a popular hard coating in various applications due to its mechanical, wear, and corrosion resistance properties. In this study, TiCN coatings were applied the NiTi substrate through physical vapor deposition (PVD) using two types of targets. A desired (TCN1 sample) was relatively achieved by Ti-Al target. However, non-stoichiometric (TCN2 obtained Ti The influence target studied on composition, microstructure, adhesion strength, porosity, also wear behaviour. With regard their properties (porosity defects), TCN2 showed more uniform with an adequate compared TCN1. Wear improved both coatings, however, presented deposited sample possesses thinner track, lower friction coefficient, smoother surface oxidation comparison TCN1 after test. Abrasion, oxidation, ploughing mechanisms observed substrate, while slight change feature negligible minor adhesive particles detected worn sample.

Language: Английский

Citations

0

Development of Functionally Graded Films and Coatings for Biomaterials: Methods, properties, and challenges – A comprehensive review DOI

Zahid Mukhtar,

Nitika Kundan,

Abhijit Dey

et al.

Tribology International, Journal Year: 2025, Volume and Issue: unknown, P. 110714 - 110714

Published: April 1, 2025

Language: Английский

Citations

0

Polydopamine-Assisted Dual Metal Ion Modification of Titanium: Enhancing Osseointegration and Antibacterial Performance DOI Creative Commons
Jingyang Kang,

Sikun Meng,

Chenhui Liu

et al.

Colloids and Surfaces B Biointerfaces, Journal Year: 2025, Volume and Issue: 253, P. 114717 - 114717

Published: April 22, 2025

Titanium (Ti) implants are widely used for tooth replacement due to their exceptional mechanical properties and high biocompatibility. However, inherently inert surface limits osteogenic potential makes them prone bacterial colonization, increasing the risk of biofilm formation implant-related infections. To address these limitations, modification Ti is essential. This study aimed enhance by coating it with polydopamine (PDA) further doping copper calcium ions. TPDA was prepared subsequently fabricate TPDA@Cu TPDA@CuCa samples. Material characterization confirmed that exhibited excellent wettability biocompatibility, Cu2 + Ca2+ being continuously stably released in liquid environments. Additionally, significantly improved protein adsorption, facilitating favorable cellular interactions. In vitro experiments demonstrated strong antimicrobial activity against Escherichia coli Staphylococcus aureus, enhanced osteoblast adhesion, mineralization, upregulated gene expression. bifunctional strategy offers a promising approach enhancing both antibacterial implants.

Language: Английский

Citations

0

Advancements in biomedical coatings: A comprehensive review of DC magnetron sputtering on Ti–6Al–4V alloy DOI

Zahid Mukhtar,

Abhijit Dey,

Nitika Kundan

et al.

Proceedings of the Institution of Mechanical Engineers Part J Journal of Engineering Tribology, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 13, 2024

This study investigates the application of DC magnetron sputtering (MS) technology for producing TiN and ion-substituted Ca-P coatings on dental implant materials, demonstrating ultimate tensile strength (UTS) 887 MPa, a modulus elasticity 11.3 × 10 6 MPa. The influence various physical vapor deposition (PVD-MS) parameters—such as substrate temperature, post-heat treatment, duration, discharge power, bias voltage—on characteristics these is examined. research evaluates advantages limitations PVD-MS in fabricating coatings, with an emphasis their impact surface topography chemical composition, which are critical factors influencing cellular behavior. reveals that while HA can enhance cell adhesion, they may also exhibit cytotoxic effects, potentially limiting growth. It compares osteogenic proliferation rates between low-crystalline highly crystalline variants Ti-based substrates, highlighting significant performance disparities. Additionally, demonstrates robust adhesion capabilities facilitates incorporation therapeutic ions, effectively replicating bioapatite properties. addition coating promotes additional strengthening mechanisms layers, leading to improved wear resistance compared alloyed substrate. Estimated values hardness range 7.2 8.4 GPa, Young's modulus, from 126 162 GPa. highlights potential creating nanostructured biodegradable metals, alloys, polymeric biomaterials. improves corrosion resistance, biocompatibility, stability, overall biomedical applications.

Language: Английский

Citations

2

Unlocking Osseointegration: Surface Engineering Strategies for Enhanced Dental Implant Integration DOI
Pankaj Sharma,

Vedante Mishra,

Sumit Murab

et al.

ACS Biomaterials Science & Engineering, Journal Year: 2024, Volume and Issue: 11(1), P. 67 - 94

Published: Dec. 2, 2024

Tooth loss is a prevalent problem faced by individuals of all ages across the globe. Various biomaterials, such as metals, bioceramics, polymers, composites ceramics and etc., have been used for manufacturing dental implants. The success implant primarily depends on its osseointegration rate. current surface modification techniques fail to imbibe basics tooth development, which can impart better mineralization osseointegration. This be improved developing an understanding developmental pathways tissue. Stimulating correct signaling through inductive material systems bring about paradigm shift in materials. review focuses pathway process that happen during formation how modifications help biomimetic mineralization, thereby enhancing We further describe effect osteoinduction, osseointegration; both vitro vivo. will us understand natural teeth development properties implants mimic turn increasing

Language: Английский

Citations

1