Nutritional Support in the Prevention and Treatment of Pressure Ulcers in Healthy Aging: A Systematic Review of Nursing Interventions in Community Care

Geriatrics, Journal Year: 2025, Volume and Issue: 10(1), P. 17 - 17

Published: Jan. 22, 2025

Introduction: Pressure ulcers (PUs) represent a significant challenge in chronic care, particularly among the elderly with reduced mobility. They result substantial socio-healthcare costs and negatively impact patients’ psychological well-being. Malnutrition is key risk factor, hindering healing increasing of complications. As such, appropriate nutritional interventions are crucial for managing PUs. However, these often underestimated clinical practice, underscoring need more comprehensive approach to elder care healthy aging. Objectives: The primary objective this study was identify best scientific evidence on implemented by nurses community settings prevent complications related Additionally, qualitative quantitative outcomes reported included studies were analyzed. Method: This systematic review conducted following PRISMA international guidelines. Searches performed PubMed, Scopus, Embase, CINAHL databases. A predefined search strategy using Boolean operators employed, two researchers independently selected papers, third researcher resolving any discrepancies. Additional sources manual reviews minimize selection bias. Results: Out 1003 records, 6 included. Findings indicate that play fundamental role PUs through specific intervention assistance processes. These healthcare professionals pivotal prevention, rehabilitation vulnerable individuals Conclusions: Nurses strategic management within frail populations. With support plays both preventing accelerating Policymakers encouraged invest nursing roles enhance contexts, supporting aging lifestyle medicine approaches.

Language: Английский

Characterization of Circulating Vesicles of Complicated and Uncomplicated Systemic Sclerosis Patients and Their Role in Vascular Dysfunction

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(6), P. 2380 - 2380

Published: March 7, 2025

Extracellular vesicles (EVs) could be involved in the onset of systemic sclerosis (SSc) through modulation vascular function. Anyway, available data are contradictory, and further investigation would necessary to clarify this aspect. Here, we characterized circulating EVs isolated from SSc patients evaluated their effects on human endothelial cells (HUVECs) smooth muscle cells. In 13 complicated 27 uncomplicated five healthy controls (HCs), analyzed size, concentration, surface marker expression. addition, were used stimulate HUVECs, cell viability, mitochondrial membrane potential, nitric oxide (NO) reactive oxygen species (MitoROS) release. cells, calcium movement examined. The results showed that expressed markers T-lymphocyte/platelet/endothelial origin larger more concentrated than those HCs. reduced viability potential increased NO MitoROS release HUVECs intracellular conclusion, found a specific pattern for patients, which have pathogenic role direct actions

Language: Английский