A single-cell RNA sequencing dataset of peripheral blood cells in long COVID patients on herbal therapy
Scientific Data,
Journal Year:
2025,
Volume and Issue:
12(1)
Published: Jan. 30, 2025
Language: Английский
Course of General Fatigue in Patients with Post-COVID-19 Conditions Who Were Prescribed Hochuekkito: A Single-Center Exploratory Pilot Study
Journal of Clinical Medicine,
Journal Year:
2025,
Volume and Issue:
14(4), P. 1391 - 1391
Published: Feb. 19, 2025
Background:
After
the
start
of
COVID-19
pandemic,
general
fatigue
in
patients
with
long
COVID
and
post-COVID-19
conditions
(PCC)
became
a
medical
issue.
Although
there
is
lack
evidence-based
treatments,
Kampo
medicine
(traditional
Japanese
medicine)
has
gained
attention
Japan.
At
an
outpatient
clinic
Japan
specializing
COVID,
24%
all
prescriptions
were
medicines,
72%
hochuekkito.
However,
been
no
prospective,
quantitative
study
on
course
PCC
who
prescribed
The
aim
this
was
to
clarify
those
patients.
Methods:
This
included
aged
18
years
or
older
visited
specialized
at
Okayama
University
Hospital
consented
participate
after
being
We
reviewed
backgrounds
patients,
we
evaluated
patients'
assessment
scale
person
online.
Results:
Twenty
enrolled
from
September
December
2023.
average
age
42.9
(SD:
15.8
years)
12
(60%)
female.
hochuekkito
administration,
score
decreased
35.9
5.9)
initial
visit
31.2
9.4)
8
weeks,
indicating
trend
for
improvement
(difference:
4.7;
95%
CI:
0.5-8.9).
Conclusions:
A
observed
hochuekkito,
potential
benefit
such
General
can
be
classified
as
post-infectious
syndrome
considered
condition
qi
deficiency
medicine,
which
appropriately
indicated.
Language: Английский
Kyungok-go for fatigue in patients with long COVID: Double-blind, randomized, multicenter, pilot clinical study protocol
PLoS ONE,
Journal Year:
2025,
Volume and Issue:
20(4), P. e0319459 - e0319459
Published: April 1, 2025
The
most
common
symptom
reported
by
patients
after
recovery
from
coronavirus
disease
2019
(COVID-19)
is
fatigue.
However,
robust
clinical
evidence
supporting
the
effectiveness
of
treatments
and
interventions
for
fatigue
in
COVID-19
survivors
lacking.
This
pilot
trial
aims
to
assess
safety
efficacy
Kyungok-go,
a
herbal
preparation
targeting
fatigue,
recovering
COVID-19.
study
will
include
100
participants
with
persistent
more
than
12
weeks
recovery.
They
be
randomly
allocated
into
two
groups:
Kyungok-go
group
(n
=
50)
placebo
50).
or
administered
twice
daily
weeks,
assessed
at
4-week
intervals.
primary
outcome
change
Fatigue
Severity
Scale
score.
Secondary
outcomes
cognitive
function,
physical
quality
life,
depression,
sleep
quality,
medication
adherence,
feasibility.
first
attempt
investigate
relieving
related
long
COVID.
results
are
expected
contribute
establishment
knowledge
base
reveal
potential
medicine
prescriptions
managing
sequelae
Trial
registration
number:
KCT0008789
.
Language: Английский