Unveiling the Miracle Tree: Therapeutic Potential of Moringa oleifera in Chronic Disease Management and Beyond DOI Creative Commons
Edgar Yebrán Villegas-Vázquez, Rocío Gómez-Cansino, Gabriel Marcelino-Pérez

et al.

Biomedicines, Journal Year: 2025, Volume and Issue: 13(3), P. 634 - 634

Published: March 5, 2025

Moringa oleifera (MO) has gained recognition as a potent natural intervention for preventing and managing chronic diseases (CDs) due to its diverse phytochemical composition pharmacological properties. Rich in antioxidants, polyphenols, flavonoids, glucosinolates, MO exerts anti-inflammatory, anti-hyperglycemic, cardioprotective, anti-obesity effects. These properties make it valuable therapeutic agent CDs, including diabetes, cardiovascular diseases, obesity, neurodegenerative disorders, cancer. MO’s ability modulate oxidative stress inflammation—key drivers of CDs—highlights significant role disease prevention treatment. enhances insulin sensitivity, regulates lipid profiles blood pressure, reduces inflammation, protects against damage. also modulates key signaling pathways involved cancer liver prevention. Studies suggest that extracts possess anticancer activity by modulating apoptosis, inhibiting tumor cell proliferation, interacting with pathways, YAP/TAZ, Nrf2-Keap1, TLR4/NF-κB, Wnt/β-catenin. However, challenges such variability bioactive compounds, taste acceptability, inconsistent clinical outcomes limit their widespread application. While preclinical studies support efficacy, large-scale trials, standardized formulations, advanced delivery methods are needed optimize potential. multifunctional applications promising sustainable solution combating especially resource-limited settings.

Language: Английский

Unveiling the Miracle Tree: Therapeutic Potential of Moringa oleifera in Chronic Disease Management and Beyond DOI Creative Commons
Edgar Yebrán Villegas-Vázquez, Rocío Gómez-Cansino, Gabriel Marcelino-Pérez

et al.

Biomedicines, Journal Year: 2025, Volume and Issue: 13(3), P. 634 - 634

Published: March 5, 2025

Moringa oleifera (MO) has gained recognition as a potent natural intervention for preventing and managing chronic diseases (CDs) due to its diverse phytochemical composition pharmacological properties. Rich in antioxidants, polyphenols, flavonoids, glucosinolates, MO exerts anti-inflammatory, anti-hyperglycemic, cardioprotective, anti-obesity effects. These properties make it valuable therapeutic agent CDs, including diabetes, cardiovascular diseases, obesity, neurodegenerative disorders, cancer. MO’s ability modulate oxidative stress inflammation—key drivers of CDs—highlights significant role disease prevention treatment. enhances insulin sensitivity, regulates lipid profiles blood pressure, reduces inflammation, protects against damage. also modulates key signaling pathways involved cancer liver prevention. Studies suggest that extracts possess anticancer activity by modulating apoptosis, inhibiting tumor cell proliferation, interacting with pathways, YAP/TAZ, Nrf2-Keap1, TLR4/NF-κB, Wnt/β-catenin. However, challenges such variability bioactive compounds, taste acceptability, inconsistent clinical outcomes limit their widespread application. While preclinical studies support efficacy, large-scale trials, standardized formulations, advanced delivery methods are needed optimize potential. multifunctional applications promising sustainable solution combating especially resource-limited settings.

Language: Английский

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