Nanofiber Application in Wound Healing DOI
Fatimah Ahmedy,

Nur Syazana Aqila Mhd Sazuli,

Lubna Abdul Kadir

et al.

IGI Global eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 289 - 326

Published: April 11, 2025

Nanofiber technology presents significant potential across various medical applications, with particular emphasis on its role in wound healing. This chapter examines the ability of nanofibers to mimic extracellular matrix, facilitating critical processes such as cell adhesion, migration, nutrient and oxygen delivery, inflammation modulation, controlled release bioactive molecules. These properties position optimal candidates for advanced dressings, biodegradable scaffolds, cell-seeded constructs. Empirical studies substantiate their efficacy mitigating inflammation, preventing infections, minimizing scar formation. However, challenges persist, including issues related scalability, cost-effectiveness, mechanical stability, biocompatibility, regulatory approval. concludes by addressing these outlining research gaps that must be bridged fully harness nanofiber technology, particularly long-term safety, mechanistic insights, adaptation low-resource settings.

Language: Английский

Nanofiber Application in Wound Healing DOI
Fatimah Ahmedy,

Nur Syazana Aqila Mhd Sazuli,

Lubna Abdul Kadir

et al.

IGI Global eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 289 - 326

Published: April 11, 2025

Nanofiber technology presents significant potential across various medical applications, with particular emphasis on its role in wound healing. This chapter examines the ability of nanofibers to mimic extracellular matrix, facilitating critical processes such as cell adhesion, migration, nutrient and oxygen delivery, inflammation modulation, controlled release bioactive molecules. These properties position optimal candidates for advanced dressings, biodegradable scaffolds, cell-seeded constructs. Empirical studies substantiate their efficacy mitigating inflammation, preventing infections, minimizing scar formation. However, challenges persist, including issues related scalability, cost-effectiveness, mechanical stability, biocompatibility, regulatory approval. concludes by addressing these outlining research gaps that must be bridged fully harness nanofiber technology, particularly long-term safety, mechanistic insights, adaptation low-resource settings.

Language: Английский

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