Post-COVID dysautonomias: what we know and (mainly) what we don’t know

Nature Reviews Neurology, Journal Year: 2024, Volume and Issue: 20(2), P. 99 - 113

Published: Jan. 11, 2024

Language: Английский

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Hypertension Related Co-Morbidities and Complications in Women of Sub-Saharan Africa: A Brief Review

Circulation Research, Journal Year: 2024, Volume and Issue: 134(4), P. 459 - 473

Published: Feb. 15, 2024

Hypertension is the leading cause of cardiovascular disease in women, and sub-Saharan African (SSA) countries have some highest rates hypertension world. Expanding knowledge causes, management, awareness its co-morbidities worldwide an effective strategy to mitigate harms, decrease morbidities mortality, improve individual quality life. Hypertensive disorders pregnancy (HDPs) are a particularly important subset hypertension, as major stress test system can be first instance which clinically apparent. In SSA, women experience higher incidence HDP compared with other regions. However, region has yet adopt treatment preventative strategies for HDP. This delay stems from insufficient awareness, lack clinical screening prevention programs. this brief literature review, we will address long-term consequences women. We evaluate effects uncontrolled SSA by including research on heart disease, stroke, kidney peripheral arterial Limitations exist number studies SSA; therefore, use data across globe, comparing contrasting approaches similar dissimilar populations. Our review highlights urgent need prioritize public health, clinical, bench discover cost-effective that lives living SSA.

Language: Английский

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Cholesterol, triglycerides, HDL, and nitric oxide as determinants of resting heart rate variability in non-hospitalized mild post-COVID individuals: a cross-sectional study

BMC Cardiovascular Disorders, Journal Year: 2025, Volume and Issue: 25(1)

Published: Jan. 31, 2025

Abstract Background The association between plasma lipids, nitric oxide (NO) and cardiovascular risk has been well documented in the literature, however, these outcomes heart rate variability (HRV) COVID-19 remains incipient as there is no scientific evidence that investigated this outcome. Objective Investigate whether metabolic may be associated with cardiac autonomic behavior arising from short-term HRV variables non-hospitalized mild post-COVID individuals. Methods This a cross-sectional study. Individuals of both sexes, aged ≥ 18 years, who tested positive for SARS-CoV-2 according to RT-PCR test, without need hospitalization, were included. was collected supine position at least 10 min later analysis Kubios software. Metabolic [high density lipoprotein (HDL) (mg/dL), cholesterol triglycerides (mg/dL) NO (µmol/L)] through blood sample. Results Seventy-three individuals included (post-COVID = 32; control 41). worse group when compared ( p < 0.05). Cholesterol, HDL, showed significant correlations indices. Regression models indicated triglycerides, NO, explain up 30.3% variations certain indices, suggesting an impact on modulation. Conclusion There relationship COVID-19. are 16.6% 30.30% resting Clinical trial number Not applicable.

Language: Английский

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Contactless and short‐range vital signs detection with doppler radar millimetre‐wave (76–81 GHz) sensing firmware

Healthcare Technology Letters, Journal Year: 2024, Volume and Issue: 11(6), P. 427 - 436

Published: Feb. 27, 2024

Abstract Vital signs such as heart rate (HR) and respiration (RR) are essential physiological parameters that routinely used to monitor human health bodily functions. They can be continuously monitored through contact or contactless measurements performed in the home a hospital. In this study, Doppler radar W‐band sensing system was for short‐range, vital sign estimation. Frequency‐modulated continuous wave (FMCW) were reduce influence of patient's micromotion. Sensing software developed process received chirps filter extract heartbeat breathing rhythm signals. The proposed eliminates need electrodes, electric patches, photoelectric sensors, conductive wires typical methods. operates at 76–81 GHz FMCW mode detect objects on basis changes frequency phase. obtained signals precisely HR RR with minimal noise interference. laboratory setting, heartbeats healthy young participants measured, their estimated frequency‐ time‐domain analyses. experimental results confirmed feasibility mm‐wave short‐range detection signs.

Language: Английский

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Effects of Covid-19 on the autonomic nervous system in elite athletes assessed by heart rate variability

Sport Sciences for Health, Journal Year: 2023, Volume and Issue: 19(4), P. 1269 - 1280

Published: May 18, 2023

Covid-19 is a viral airway and systemic infection which can negatively affect the function of autonomic nervous system. Cardiovascular essential for peak athletic performance. The aim this study was to assess effects disease on system German elite athletes using heart rate variability (HRV).60 (aged 22.88 ± 4.71 years) were recruited, 30 whom had undergone disease. Heart (HR), blood pressure (BP) (HRV) measured during rest an orthostatic challenge.At after stress root mean square successive differences (RMSDD) significantly lower in (COV) than control (CON) (p = 0.002 p 0.004, respectively); higher 0.001). COV showed greater reduction elevation CON, but change RMSSD did not differ challenge.These results show cardiac parasympathetic activity cardiovascular Covid-19. These findings further understanding physiology athletes. may be helpful tool return-to-play assessment athletes.The online version contains supplementary material available at 10.1007/s11332-023-01067-7.

Language: Английский

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Reactive hyperemia index as an integrated marker in prediction of bleeding and cardiovascular death in ACS

International Journal of Cardiology, Journal Year: 2023, Volume and Issue: 382, P. 85 - 86

Published: March 23, 2023

Language: Английский

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The Status of Intima-Media Thickness of Bilateral Carotid Arteries in the Postinfection Phase of SARS-CoV-2

Journal of diagnostic medical sonography, Journal Year: 2024, Volume and Issue: 40(6), P. 548 - 553

Published: July 23, 2024

Objective: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affects the cardiovascular system by activating systemic inflammatory responses that cause vascular dysfunction. However, long-term effects of SARS-CoV-2 on remain unclear. Therefore, this study aimed to compare carotid intima-media thickness (cIMT) between patients who have recovered from Coronavirus disease-2019 (COVID-19) and healthy individuals evaluate feasibility complications in postinfection phase COVID-19. Materials Methods: In cross-sectional study, cIMT was compared 47 with severe COVID-19 42 without a history (controls) using Doppler sonography. Demographic sonographic data were analyzed SPSS version 26 statistical software. Results: A total young adults (30.8 ± 5.78 years, 7 men 40 women) evaluated 3 6 months after hospitalization for COVID-19, (26.5 5.85 5 37 women). The mean right left significantly lower than (right cIMT: case group, 0.38 05 mm vs control 0.40 0.02 mm, P < .01; 0.05 0.02, .01). Conclusion: positive associated controls. cohort, endothelial dysfunction may not been main driver patients. more studies should be conducted relationship complications.

Language: Английский

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Viral infections in cardiometabolic risk and disease between old acquaintances and new enemies

Published: Dec. 27, 2023

Atherosclerosis is a chronic disease, characterized by inflammation, endothelial dysfunction, and lipid deposition in the vessel. Although many major, well-identified risk factors for atherosclerosis [e.g., hyperlipidemia, hypertension, type 2 diabetes (T2D), smoking habit, obesity] explain lot about risk, there considerable number of patients who develop atherosclerotic damage undergo adverse events without presenting any these established modifiable factors. This observation has stimulated an urgent need to expand knowledge towards identification additional, less that may help assessment fill gap cardiovascular (CV) setting. Among them, hypothesis possible relationship between viral infectious agents risen since early 1900s. However, still great deal debate regarding onset progression CV disease relation roles pathogens (as active inducers or bystanders), host genomic counterparts, environmental triggers, affecting both virus abundance composition communities. Accordingly, aim this review discuss current state on process, with particular focus two environmental-related viruses, as examples familiar (influenza) unfamiliar [severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)] triggers.

Language: Английский

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Obesity, COVID-19 severity, and mortality

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 507 - 521

Published: Jan. 1, 2024

Language: Английский

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Central artery pulse pressure, not central arterial stiffness impact on all-cause mortality in patients with viral pneumonia infection

BMC Infectious Diseases, Journal Year: 2024, Volume and Issue: 24(1)

Published: Oct. 21, 2024

COVID-19 viral pneumonia can result in increased arterial stiffness, along with cardiac and systemic inflammatory responses. This study aimed to investigate the association between inflammation severity, all-cause mortality patients COVID-19. In this study, anthropometric data, infection blood tests were analyzed. Arterial stiffness was assessed using non-invasive assessment indices, including velocity pulse index (AVI) central pressure (CAPP). Infection volumes percentages for whole lungs, most lobes, segments extracted from CT images artificial intelligence-based quantitative analysis software. The relationship hemodynamics, investigated. multivariable Cox regression analysis, high CAPP significantly associated (hazard ratio: 0.263, 95% CI, 0.073–0.945, p = 0.041). Whole lung independently CAPP, an area under curve (AUC) of 0.662 a specificity 89.09%. High but not AVI, demonstrated independent prognostic value due infection. Evaluating parameter could help risk improve diagnostic therapeutic strategies infections.

Language: Английский

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