Association between cardiometabolic index and hypertension: National Health and Nutrition Examination Survey (NHANES) 2017–2020 DOI Creative Commons

Zefeng Yan,

Jinxin Zhao,

Congzhe Chen

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 8, 2024

Abstract Objective Cardiometabolic index (CMI) is a well promising indicator for predicting obesity-related diseases, but its predictive value hypertension unclear. This study aimed to investigate the relationship between CMI and evaluate of hypertension.Methods was cross-sectional with sample size 7897 U.S. adults sourced from NHANES 2017–2020. calculated by multiplying ratio triglycerides high-density lipoprotein cholesterol (TG/HDL-C) waist-to-height (WHtR). Multivariate logistic regression analysis used systematically hypertension. To determine whether there linear or nonlinear restricted cubic spline regression.The subgroup analyses were conducted in order scrutinize reliability robustness across different subgroups.Results The average age participants 50.98 years, males accounting 48.4% females 51.6%. Subjects higher exhibited significantly increased risk odds (OR) 1-standard-deviation increase 3.38(2.69–4.23) after adjusting various confounding factors. Further showed that significant additive interactions gender, waist circumference(WC), HDL-C, TG glycohemoglobin ( p interaction < 0.05). Restricted (RCS) identified one inflection points: point at 0.4934. Individuals level below 0.4934 had low developing Conclusions: strongly positively associated can be reference predictor High excellent diagnostic performance hypertension, which enable important clinical early identification screening

Language: Английский

Cardiometabolic index as a predictor of gallstone risk: evidence from NHANES 2017–2020 DOI Creative Commons
Hongxing Zheng, Bo Wu,

Caixiang Zhuang

et al.

BMC Gastroenterology, Journal Year: 2025, Volume and Issue: 25(1)

Published: April 3, 2025

Language: Английский

Citations

0
Lipid metabolism reprogramming in chronic obstructive pulmonary disease DOI Creative Commons
Qianqian Liang, Yide Wang, Zheng Li

et al.

Molecular Medicine, Journal Year: 2025, Volume and Issue: 31(1)

Published: April 7, 2025

Abstract Chronic Obstructive Pulmonary Disease (COPD) is a complex and diverse respiratory disorder, characterized by ongoing symptoms restricted airflow. The major clinical manifestations typically encompass chronic cough, sputum production, wheezing. main pathological characteristics involve infiltration of inflammatory cells, overproduction mucus, damage to the alveolar walls. underlying causes COPD are remain incompletely elucidated, thought originate from combined effect various factors. Lipids, as hydrophobic molecules, fulfill three fundamental functions: energy storage, membrane biosynthesis, signal transduction. Lipid metabolism intricately intertwined with metabolic pathways plays pivotal role in pathogenesis COPD. Delving into lipid metabolism, well particular modifications roles molecules paramount importance context This review primarily aims elucidate fatty acid onset progression Additionally, it examines potential reprogramming promising therapeutic approach, illuminating new paths for management treatment this disabling condition.

Language: Английский

Citations

0
Association between cardiometabolic index and bone mineral density among adolescents in the United States DOI Creative Commons
Haobiao Liu, Rongqi Xiang,

Chenyue Liu

et al.

Frontiers in Endocrinology, Journal Year: 2025, Volume and Issue: 16

Published: May 8, 2025

Objectives The cardiometabolic index (CMI) serves as a comprehensive metric for evaluating health, and is correlated with several health outcomes. However, research examining the relationship between CMI bone mineral density (BMD), particularly in adolescent populations, remains limited warrants further investigation. Methods weighted multiple linear regression analysis was conducted to elucidate association BMD. Results Our study ultimately included 1,514 participants. After adjusting pertinent covariates, we observed that per-unit increases corresponded reductions BMD by 0.052 g/cm 2 femoral neck ( β =-0.052, 95% CI: -0.087 -0.018) 0.048 lumbar spine (L1-L4) =-0.048, -0.085 -0.011). In quartile analyses, individuals highest displayed significantly reduced at =-0.036, -0.064 -0.007) =-0.041, -0.070 -0.011) compared those lowest P &lt;0.05). No statistical significance detected total femur, trochanter, intertrochanter sites. Furthermore, stratified analyses indicated no significant interactions involving age, sex, or race relation Conclusions population, inversely related These findings highlight potential link health. Future longitudinal investigations are warranted determine causal relationships underlying mechanisms.

Language: Английский

Citations

0
Association between cardiometabolic index and hypertension: National Health and Nutrition Examination Survey (NHANES) 2017–2020 DOI Creative Commons

Zefeng Yan,

Jinxin Zhao,

Congzhe Chen

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 8, 2024

Abstract Objective Cardiometabolic index (CMI) is a well promising indicator for predicting obesity-related diseases, but its predictive value hypertension unclear. This study aimed to investigate the relationship between CMI and evaluate of hypertension.Methods was cross-sectional with sample size 7897 U.S. adults sourced from NHANES 2017–2020. calculated by multiplying ratio triglycerides high-density lipoprotein cholesterol (TG/HDL-C) waist-to-height (WHtR). Multivariate logistic regression analysis used systematically hypertension. To determine whether there linear or nonlinear restricted cubic spline regression.The subgroup analyses were conducted in order scrutinize reliability robustness across different subgroups.Results The average age participants 50.98 years, males accounting 48.4% females 51.6%. Subjects higher exhibited significantly increased risk odds (OR) 1-standard-deviation increase 3.38(2.69–4.23) after adjusting various confounding factors. Further showed that significant additive interactions gender, waist circumference(WC), HDL-C, TG glycohemoglobin ( p interaction < 0.05). Restricted (RCS) identified one inflection points: point at 0.4934. Individuals level below 0.4934 had low developing Conclusions: strongly positively associated can be reference predictor High excellent diagnostic performance hypertension, which enable important clinical early identification screening

Language: Английский

Citations

0