Springer eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 26
Published: Jan. 1, 2024
Language: Английский
Iranian Polymer Journal, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 10, 2025
Language: Английский
Citations
0
Journal of Nutritional Science, Journal Year: 2025, Volume and Issue: 14
Published: Jan. 1, 2025
Green tea, a plant rich in bioactive compounds, has been highlighted for its beneficial effects. In the present systematic review and meta-analysis of randomised controlled trials (RCTs), impact green tea on inflammatory oxidative markers is investigated. Using pre-defined keywords, online databases (PubMed, Scopus, Web Science Core Collection, Google Scholar) were searched relevant articles, published from inception up to February 2024. The outcomes included C-reactive protein (CRP), tumour necrosis factor-α (TNF-α), interleukin-6 (IL-6), interleukin-1 beta (IL-1β), total antioxidant capacity (TAC), malondialdehyde (MDA), superoxide dismutase (SOD), glutathione peroxidase (GPX). Analyses subgroups, linear, non-linear associations also carried out. Out 1264 records initially retrieved, 38 RCTs included. Supplementation with improved following indicators: IL-1β (weighted mean difference (WMD): -0.10 pg/mL; 95% CI: -0.15, -0.06), MDA (WMD: -0.40 mcmol/L; 95 % -0.63, -0.18), TAC 0.09 mmol/L; 0.05, 0.13), SOD 17.21 u/L; 3.24, 31.19), GPX 3.90 1.85, 5.95); but failed improve others, including CRP 0.01 mg/L; -0.14, 0.15), IL-6 -0.34 CI:-0.94, 0.26), TNF-α -0.07 -0.42, 0.28). can body's status. However, results showed no significant effect markers, except IL-1β. Further studies are needed determine effectiveness particularly
Language: Английский
Citations
0
Critical Reviews in Food Science and Nutrition, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 26
Published: April 15, 2024
Inflammatory cascades of the dysregulated inflammatory pathways in COVID-19 can cause excessive production pro-inflammatory cytokines and chemokines leading to cytokine storm syndrome (CSS). The molecular involved may be targeted for discovery new anti-inflammatory agents. Many plant extracts have been used clinically management COVID-19, however, their immunosuppressive activities were mainly investigated based on silico activity. Dietary flavonoids such as quercetin, luteolin, kaempferol, naringenin, isorhamnetin, baicalein, wogonin, rutin commonly identified responsible inhibitory effects. present review critically analyzes effects mechanisms phytochemicals, including dietary compounds against (CS) hyperinflammation via inhibition altered triggered by SARS-CoV-2, published since emergence December 2019. Only a few nanocurcumin, melatonin, 6-shagoal, resveratrol, andrographolide, colchicine either or preliminary clinical studies evaluate COVID-19. Sufficient pre-clinical safety efficacy phytochemicals must performed prior proper develop them into therapeutic adjuvants prevention treatmemt symptoms.
Language: Английский
Citations
3
International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(15), P. 8481 - 8481
Published: Aug. 3, 2024
The acute manifestations of coronavirus disease 2019 (COVID-19) exhibit the hallmarks sepsis-associated complications that reflect multiple organ failure. inflammatory cytokine storm accompanied by an imbalance in pro-inflammatory and anti-inflammatory host response to severe respiratory syndrome 2 (SARS-CoV-2) infection leads critical septic shock. sepsis signature severely afflicted COVID-19 patients includes cellular reprogramming dysfunction high mortality rates, emphasizing importance improved clinical care advanced therapeutic interventions for associated with COVID-19. Phytochemicals functional foods nutraceutical have incredible impact on healthcare system, which prevention and/or treatment chronic diseases. Hence, present review, we aim explore pathogenesis disrupts physiological homeostasis body, resulting damage. Furthermore, summarized diverse pharmacological properties some potent phytochemicals, can be used as well nutraceuticals against SARS-CoV-2 infection. phytochemicals explored this article include quercetin, curcumin, luteolin, apigenin, resveratrol, naringenin, are major phytoconstituents our daily food intake. We compiled findings from various studies, including trials humans, more into potential each phytochemical COVID-19, highlights their possible pathogenesis. conclude review will open a new research avenue exploring phytochemical-derived agents preventing or treating life-threatening
Language: Английский
Citations
1
Springer eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 26
Published: Jan. 1, 2024
Language: Английский
Citations
0