Multifunctional, Novel Formulation for Repairing Photoaged and Sun-Damaged Skin: Insights from In Vitro, Ex Vivo, and In Vivo Studies DOI Creative Commons

María Moneo-Sánchez,

Nagore de Pablo,

Leire Arana-Pascual

et al.

Cosmetics, Journal Year: 2024, Volume and Issue: 11(6), P. 224 - 224

Published: Dec. 17, 2024

Prolonged sun exposure disrupts the skin’s structural, mechanical, and functional properties, accelerating aging contributing to skin disorders. To counteract these effects, we developed a formulation containing potent antioxidant, anti-inflammatory, moisturizing, reparative ingredients protect repair sun-damaged skin. The efficacy of was evaluated through in vitro, ex vivo, vivo studies. Results demonstrated that reduced oxidative stress suppressed production pro-inflammatory cytokines interleukin-6 (IL-6) interleukin-8 (IL-8), as well lactate dehydrogenase (LDH) secretion, photodamaged model, nearly reaching levels observed undamaged It also restored collagen levels, improving structural integrity. In no adverse reactions were when used for 28 or 56 days. improved hydration by up 46%, transepidermal water loss 20%, increased luminosity 70%, hyperpigmented spots 14%. enhanced firmness elasticity 30% wrinkle volume density 53% 19%, respectively. These findings demonstrate formulation’s active effectively target pathways altered UV exposure, offering considerable potential preventing reversing sun-induced damage while both appearance functionality

Language: Английский

Dragon fruit: Exploring bioactive compounds and their promising role in functional food innovation and value-added products DOI

Smriti Kumari,

Diksha Thakur, S. K. Singh

et al.

Journal of Food Composition and Analysis, Journal Year: 2025, Volume and Issue: unknown, P. 107370 - 107370

Published: Feb. 1, 2025

Language: Английский

Citations

0

Pectinase‐Driven Optimization of Pectin Hydrolysis for Enhanced Clarity, Anthocyanin Retention, and Consumer Appeal in Red Dragon Fruit Mint Flavored Beverage DOI Creative Commons
Binh An Pham, Ngoc Duc Vu,

Pham Hong Phan

et al.

Journal of Food Processing and Preservation, Journal Year: 2024, Volume and Issue: 2024(1)

Published: Jan. 1, 2024

This study is aimed at analyzing, evaluating, and optimizing the pectin hydrolysis process to improve quality of carbonated beverages made from red dragon fruit combined with mint flavor. Red fruit, rich in nutrients antioxidants, presents challenges beverage processing due its high content, which affects clarity anthocyanin stability. The research investigates impact various parameters, including enzyme concentration, time, temperature, on juice content. Using a central composite design model, optimal conditions were determined maximize Sensory evaluation during blending was also conducted assess consumer acceptance, focusing clarity, color, flavor, taste, total acceptability. optimum found yield maximum (52.763%) content (224.414 mg C3G/L). indicated that 20% concentration 0.12% citric acid, 13°Bx, 0.30% flavor provided best acceptance. demonstrates potential for producing high‐quality, appealing, nutritious contributing healthier more sustainable consumption trends.

Language: Английский

Citations

0

Multifunctional, Novel Formulation for Repairing Photoaged and Sun-Damaged Skin: Insights from In Vitro, Ex Vivo, and In Vivo Studies DOI Creative Commons

María Moneo-Sánchez,

Nagore de Pablo,

Leire Arana-Pascual

et al.

Cosmetics, Journal Year: 2024, Volume and Issue: 11(6), P. 224 - 224

Published: Dec. 17, 2024

Prolonged sun exposure disrupts the skin’s structural, mechanical, and functional properties, accelerating aging contributing to skin disorders. To counteract these effects, we developed a formulation containing potent antioxidant, anti-inflammatory, moisturizing, reparative ingredients protect repair sun-damaged skin. The efficacy of was evaluated through in vitro, ex vivo, vivo studies. Results demonstrated that reduced oxidative stress suppressed production pro-inflammatory cytokines interleukin-6 (IL-6) interleukin-8 (IL-8), as well lactate dehydrogenase (LDH) secretion, photodamaged model, nearly reaching levels observed undamaged It also restored collagen levels, improving structural integrity. In no adverse reactions were when used for 28 or 56 days. improved hydration by up 46%, transepidermal water loss 20%, increased luminosity 70%, hyperpigmented spots 14%. enhanced firmness elasticity 30% wrinkle volume density 53% 19%, respectively. These findings demonstrate formulation’s active effectively target pathways altered UV exposure, offering considerable potential preventing reversing sun-induced damage while both appearance functionality

Language: Английский

Citations

0