Design, Synthesis and Application of 1,4‐disubstituted 1,2,3‐triazole Based Chemosensors: A Promising Avenue DOI Open Access

Poonam Malik,

M. Yadav,

Ravi Bhushan

et al.

The Chemical Record, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 23, 2024

Abstract The 1,2,3‐triazole‐based chemosensors, synthesized through Cu(I)‐catalyzed azide‐alkyne cycloaddition via ‘click chemistry’, offer a straightforward yet highly effective method for detecting metal cations and anions with remarkable accuracy, selectivity sensitivity, making them invaluable across various fields such as chemistry, pharmacology, environmental science biology. selective recognition of these ions is crucial due to their significant roles in biological physiological processes, where even slight concentration variations can have major consequences. article reviews literature from 2017 2024, highlighting advancements the synthesis ligands application (along sensing mechanism) detection causing health hazards. aspects been discussed sequentially transition‐, inner metals s or p block periodic table.

Language: Английский

A new 1,2,3-triazole functionalized bis-organosilane as a plant growth regulator via in vitro and in silico approach DOI
Gurjaspreet Singh,

Swati Devi,

Akshpreet Singh

et al.

Inorganica Chimica Acta, Journal Year: 2025, Volume and Issue: unknown, P. 122559 - 122559

Published: Jan. 1, 2025

Language: Английский

Citations

1
Organosilane Functionalized Graphene Oxide Nanocomposite as Fluorescent Chemosensor for the Detection of Tyrosine in Aqueous Medium DOI Open Access
Gurjaspreet Singh,

Swati Devi,

Akshpreet Singh

et al.

Applied Organometallic Chemistry, Journal Year: 2025, Volume and Issue: 39(3)

Published: Feb. 20, 2025

ABSTRACT In the present article, a selective and efficient sensor based on organosilane functionalized graphene oxide nanocomposites has been synthesized for fluorometric detection of tyrosine (Tyr). The 1,2,3‐triazole by condensation reaction between 4‐(methylthio) aniline alkylated benzaldehyde followed azide‐alkyne cycloaddition using Cu (I) catalyst. fabricated nanoparticles obtained graphene‐functionalized ( GO‐Silane ) was characterized FTIR XRD. morphology nanocomposite film analyzed scanning electron microscopy. photophysical properties were studied which established its with limit values 1.04 × 10 −8 M response time 8 s. strong coordinated interactions Tyr have confirmed from spectra GO‐Silane‐Tyr complex. competitive amino acid interference assay successfully demonstrated selectivity sensor.

Language: Английский

Citations

1
A Comprehensive Review on Recent Advances of Remarkable Scaffold Triazole based Schiff Base: Synthesis and Photoresponsive Chemosensors for Al3+ Ion Detection DOI
Umme Salma,

Md. Zafer Alam,

Suhail Ahmad

et al.

Journal of Fluorescence, Journal Year: 2025, Volume and Issue: unknown

Published: March 21, 2025

Language: Английский

Citations

1
Synthesis of Acetylene‐Functionalized Schiff base for Selective Detection of Al(III) and Exploring Its Antibacterial Properties via In Silico and In Vivo Approach DOI
Gurjaspreet Singh,

Mithun,

Anita Devi

et al.

ChemistrySelect, Journal Year: 2024, Volume and Issue: 9(41)

Published: Oct. 29, 2024

Abstract The identification of perilous metal ions and the treatment diseases induced by microorganisms are critical areas requiring attention. We report herein design development an acetylene‐functionalized Schiff base compound 4 , using a low‐cost straightforward approach. This exhibits dual functions in detection harmful ions, particularly Al(III), as well prevention disorders caused bacteria, specifically Staphylococcus aureus ( S. ) Bacillus subtilis B. ). It was characterized through utilization diverse spectroscopic techniques, such NMR 1 H 13 C), FT‐IR, mass spectrometry. Furthermore, complete structure clarification revealed X‐ray crystallography. limit (LOD) for Al(III) is 35.5 × 10 −8 M, surpassing WHO drinking water standard 26.7 µM, underscoring high sensitivity . antibacterial activity has also been effectively evaluated on Gram‐positive bacteria. docked to proteins, which represents outstanding outcomes with binding energies −7.31 kcal/mol −7.87 kcal/mol, respectively. both vitro docking studies suggests that it possesses potential serve agent future.

Language: Английский

Citations

1
Design, Synthesis and Application of 1,4‐disubstituted 1,2,3‐triazole Based Chemosensors: A Promising Avenue DOI Open Access

Poonam Malik,

M. Yadav,

Ravi Bhushan

et al.

The Chemical Record, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 23, 2024

Abstract The 1,2,3‐triazole‐based chemosensors, synthesized through Cu(I)‐catalyzed azide‐alkyne cycloaddition via ‘click chemistry’, offer a straightforward yet highly effective method for detecting metal cations and anions with remarkable accuracy, selectivity sensitivity, making them invaluable across various fields such as chemistry, pharmacology, environmental science biology. selective recognition of these ions is crucial due to their significant roles in biological physiological processes, where even slight concentration variations can have major consequences. article reviews literature from 2017 2024, highlighting advancements the synthesis ligands application (along sensing mechanism) detection causing health hazards. aspects been discussed sequentially transition‐, inner metals s or p block periodic table.

Language: Английский

Citations

1