A compendium of 8,176 bat RNA viral metagenomes reveals ecological drivers and circulation dynamics

Nature Microbiology, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 20, 2025

Language: Английский

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Increased population susceptibility to seasonal influenza during the COVID‐19 pandemic in China and the United States

Journal of Medical Virology, Journal Year: 2023, Volume and Issue: 95(10)

Published: Oct. 1, 2023

To the best of our knowledge, no previous study has quantitatively estimated dynamics and cumulative susceptibility to influenza infections after widespread lifting COVID-19 public health measures. We constructed an imitated stochastic susceptible-infected-removed model using particle-filtered Markov Chain Monte Carlo sampling estimate time-dependent reproduction number based on surveillance data in southern China, northern United States during 2022-2023 season. compared these estimates those from 2011 2019 seasons without strong social distancing interventions determine restrictions. Compared 2011-2019 a intervention with measures, season length was 45.0%, 47.1%, 57.1% shorter States, respectively, corresponding 140.1%, 74.8%, 50.9% increase scale infections, 60.3%, 72.9%, 45.1% population influenza. Large high-intensity epidemics occurred China 2022-2023. Population increased 2019-2022, especially China. recommend promoting vaccination, taking personal prevention actions at-risk populations, monitoring changes dynamic levels other respiratory prevent potential outbreaks coming

Language: Английский

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The impact of high Humidex on the risk of hospital admissions for urinary system diseases in Lanzhou, China: A time-series Analysis

iScience, Journal Year: 2025, Volume and Issue: 28(3), P. 111968 - 111968

Published: Feb. 7, 2025

There is scant research on the association between humidex exposure and urinary system diseases. Hospitalization records from Lanzhou city were collected for period 2015 to 2019, alongside daily meteorological air pollution data study duration. Daily was calculated using temperature relative humidity indices. The employed a combined approach of generalized additive models distributed lag non-linear (DLNMs) estimate exposure-lag-response relationship hospital admissions diseases, as well subgroups diseases (urolithiasis tubule-interstitial diseases). A total 55,365 patients with included. single effect overall most significant lag13 risk (RR) = 1.066 (95% confidence interval [CI]: 1.011, 1.124), while cumulative over lag0-14 RR 1.387 CI: 1.240, 1.550). goal this establish an early warning allocate medical resources effectively reduce

Language: Английский

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The Association Between Humidex and Daily Outpatient Visits for Pediatric Respiratory Diseases in Shijiazhuang, China: A Time Series Analysis

International Journal of Public Health, Journal Year: 2025, Volume and Issue: 70

Published: March 17, 2025

At present, most studies have focused on the effects of temperature or humidity children's health, while relatively few explored combined and health. We aimed to examine impact humidex, a comprehensive index, outpatient department respiratory diseases in children. Daily visits for pediatric disorders, meteorological conditions, air pollution Shijiazhuang were recorded. From 2014 2022, we evaluated humidex disorders children using distributed lag non-linear model (DLNM). The controlled (PM2.5, NO2, SO2) wind velocity, as well day week, seasonality, long-term trend. In addition, stratified analysis was performed according different genders, ages, disease types. Humidex exposure-response curve showed "V" type. cumulative relative risks (CRR) extremely high low 1.124 (95% confidence interval [CI] = 1.030-1.228) 1.344 CI 1.136-1.590), respectively. burden attributed non-optimal 13.96% empirical CI[eCI] 7.81-19.33%), which with an AF 12.54% eCI 5.94-18.32%), only 1.42% 0.19-2.48%) due humidex. Low exposure significantly increased risk illnesses children, aged 7-14 more susceptible

Language: Английский

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The independent and joint effects of meteorological factors on influenza: A nationwide time series study in China

Urban Climate, Journal Year: 2025, Volume and Issue: 61, P. 102388 - 102388

Published: March 23, 2025

Language: Английский

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A Retrospective Analysis of Changes in Respiratory Pathogens During the Influenza Season Before and After the Relaxation of Non‐Pharmaceutical Intervention Policies

Health Science Reports, Journal Year: 2025, Volume and Issue: 8(4)

Published: April 1, 2025

ABSTRACT Background and Aims The COVID‐19 pandemic has profoundly impacted the transmission dynamics epidemiology of respiratory pathogens, primarily due to non‐pharmaceutical interventions (NPIs). This study aims evaluate effects NPIs on characteristics winter pathogens. Methods involved collection pathogen test results from all patients tested at our hospital during two distinct periods: September 2021 May 2022 2023. comparison positive rates was performed using χ 2 test. A p ‐value less than 0.05 indicates no statistical significance. Data analysis SPSS version 22.0. Results predominant 2021/2022 flu seasons identified as Inf B (1095/9309, 11.76%). Conversely, 2022/2023 seasons, emerged most prevalent (4040/18,770, 21.52%). Notably, parainfluenza virus M. pneumoniae were lower in while rate L. pneumophila higher. Furthermore, number SARS‐CoV‐2 cases increased nearly fivefold compared seasons. Conclusions findings this suggest that relaxation a notable influence certain pathogens within population. We propose implementation ongoing surveillance monitor evolutionary various particularly situations where are longer necessary.

Language: Английский

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A systematic review and meta-analysis on the association between PM2.5 exposure and increased influenza risk

Frontiers in Epidemiology, Journal Year: 2025, Volume and Issue: 5

Published: April 11, 2025

Introduction This systematic review and meta-analysis investigate the relationship between PM 2.5 exposure increased influenza risk (e.g., hospital admissions, confirmed cases), synthesizing previous findings related to pollutant effects durations. Methods We searched PubMed, Web of Science, Scopus for relevant studies up 1 January 2010, following Preferred Reporting Items Systematic reviews Meta-Analysis (PRISMA) guidelines selection analysis. Results Our included 16 found that a 10 μg/m 3 increase in daily levels was associated with an 1.5% rise (95% CI: 0.08%, 2.2%), significant variations across different temperatures lag times post-exposure. The analysis revealed heightened risks, most increases observed under extreme temperature conditions. Specifically, colder conditions were 14.2% (RR = 14.2%, 95% 3.5%, 24.9%), while warmer showed highest increase, 29.4% 29.4%, 7.8%, 50.9%). Additionally, adults aged 18–64 notably affected 4%, 2.9%, 5.1%). Discussion These results highlight 's potential impair immune responses, increasing flu susceptibility. Despite clear evidence impact on risk, gaps remain concerning timing climate effects. Future research should broaden diverse regions populations deepen understanding inform public health strategies.

Language: Английский

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Exploration of the impact of air pollutants on the influenza epidemic after the emergence of COVID-19: based on Jiangsu Province, China (2020–2024)

Frontiers in Public Health, Journal Year: 2025, Volume and Issue: 13

Published: April 14, 2025

Background Non-pharmaceutical interventions (NPIs) during the COVID-19 pandemic altered influenza transmission patterns, yet age-specific effects of air pollutants on dynamics remain unclear. Methods Utilizing surveillance data Jiangsu Province from 2020 to 2024, we integrated generalized additive quasi-Poisson regression model and distributed lag non-linear models (DLNM) quantify lagged exposure-response relationships between (NO 2 , SO PM 2.5 ) risk across young, middle-aged, older adult groups. Meteorological factors, including temperature humidity, as well implementation stages NPIs, were controlled in isolate impact transmission. Results The NO both showed significant positive all age effect is most young group (RR = 5.02, 95% CI: 4.69–5.37), while exhibited pronounced middle-aged groups 4.22, 3.36–5.30; RR 8.31, 5.77–11.96, respectively). elevated risks 1.99, 1.87–2.12) 1.45, 1.07–1.94) Interactions meteorological factors (temperature, humidity) statistically insignificant. Conclusions Air pollutant impacts are age-dependent: dominates younger populations, whereas disproportionately affects adults. These findings highlight age-related vulnerability pollution need for targeted public health strategies different population subgroups.

Language: Английский

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The Long and the Short of it: A Systematic Review and Meta-Analysis on the Impact of Pm2.5 Exposure on Influenza Risk

Published: Jan. 1, 2024

Language: Английский

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Effects of temperature on influenza activity across different populations in a subtropical region: a 7-year surveillance in Changsha, China

International Journal of Environmental Health Research, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 11

Published: Dec. 14, 2024

Changsha, a city of 10 million people in China, has complex patterns influenza activities. There is limited evidence on how temperature influences activity across different populations subtropical region. We collected surveillance data from all medical facilities Changsha City 2017 to 2023. The effects various indicators, including daily frequency influenza, influenza-like illness (ILI) rate, A (FluA) and B (FluB) were assessed using the distributed lag nonlinear model. This study revealed exhibited most significant impact activity. low (below 10°C) increased effect while high (above 25°C) primarily enhanced FluA ILI rates. aged 6-17 years was significantly stronger than other groups. research results could provide reference for prediction early warning.

Language: Английский

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