Polymers,
Journal Year:
2024,
Volume and Issue:
16(11), P. 1492 - 1492
Published: May 24, 2024
Inulin,
a
natural
polysaccharide,
has
emerged
as
promising
precursor
for
the
preparation
of
hydrogels
due
to
its
biocompatibility,
biodegradability,
and
structural
versatility.
This
review
provides
comprehensive
overview
recent
progress
in
preparation,
characterization,
diverse
applications
inulin-based
hydrogels.
Different
synthesis
strategies,
including
physical
methods
(thermal
induction
non-thermal
induction),
chemical
(free-radical
polymerization
crosslinking),
enzymatic
approaches,
are
discussed
detail.
The
unique
properties
hydrogels,
such
stimuli-responsiveness,
antibacterial
activity,
their
potential
fat
replacers,
highlighted.
Special
emphasis
is
given
drug
delivery
systems,
especially
colon-targeted
delivery,
selective
degradation
inulin
via
colonic
microflora.
ability
incorporate
both
hydrophilic
hydrophobic
drugs
further
expands
therapeutic
potential.
In
addition,
responsive
materials,
food
industry,
wound
dressings,
tissue
engineering
discussed.
While
significant
been
achieved,
challenges
prospects
optimizing
synthesis,
improving
mechanical
properties,
exploring
new
functionalities
Overall,
this
highlights
remarkable
class
biomaterials
with
immense
biomedical,
pharmaceutical,
materials
science
fields.
Journal of Composites Science,
Journal Year:
2024,
Volume and Issue:
8(11), P. 457 - 457
Published: Nov. 4, 2024
Hydrogels
play
a
crucial
role
due
to
their
high-water
content
and
3D
structure,
which
make
them
ideal
for
various
applications
in
biomedicine,
sensing,
beyond.
They
can
be
prepared
from
variety
of
biomaterials,
polymers,
combinations,
allowing
versatility
properties
applications.
include
natural
types
derived
collagen,
gelatin,
alginate,
hyaluronic
acid,
as
well
synthetic
based
on
polyethylene
glycol
(PEG),
polyvinyl
alcohol
(PVA),
polyacrylamide
(PAAm).
Each
type
possesses
distinct
properties,
such
mechanical
strength,
biodegradability,
biocompatibility,
tailored
wound
healing,
contact
lenses,
bioprinting,
tissue
engineering.
The
hydrogels
mimics
environments,
promoting
cell
growth
nutrient
waste
exchange,
supports
the
development
functional
tissues.
serve
scaffolds
engineering
applications,
including
cartilage
bone
regeneration,
vascular
engineering,
organ-on-a-chip
systems.
Additionally,
encapsulate
deliver
therapeutic
agents,
factors
or
drugs,
specific
target
sites
body.
through
three
primary
methods:
physical
crosslinking,
relies
non-covalent
interactions
entanglements
hydrogen
bonding;
chemical
forms
covalent
bonds
between
polymer
chains
create
stable
structure;
irradiation-based
where
UV
irradiation
induces
rapid
hydrogel
formation.
choice
crosslinking
method
depends
desired
hydrogel.
By
providing
biomimetic
environment,
facilitate
differentiation,
support
formation,
aid
regeneration
damaged
diseased
tissues
while
delivering
agents.
This
review
focuses
critical
advancements
processing
routes
development,
summarizing
characterization
application
hydrogels.
It
also
details
key
healing
challenges
future
perspectives
field.
Polymers,
Journal Year:
2024,
Volume and Issue:
16(11), P. 1492 - 1492
Published: May 24, 2024
Inulin,
a
natural
polysaccharide,
has
emerged
as
promising
precursor
for
the
preparation
of
hydrogels
due
to
its
biocompatibility,
biodegradability,
and
structural
versatility.
This
review
provides
comprehensive
overview
recent
progress
in
preparation,
characterization,
diverse
applications
inulin-based
hydrogels.
Different
synthesis
strategies,
including
physical
methods
(thermal
induction
non-thermal
induction),
chemical
(free-radical
polymerization
crosslinking),
enzymatic
approaches,
are
discussed
detail.
The
unique
properties
hydrogels,
such
stimuli-responsiveness,
antibacterial
activity,
their
potential
fat
replacers,
highlighted.
Special
emphasis
is
given
drug
delivery
systems,
especially
colon-targeted
delivery,
selective
degradation
inulin
via
colonic
microflora.
ability
incorporate
both
hydrophilic
hydrophobic
drugs
further
expands
therapeutic
potential.
In
addition,
responsive
materials,
food
industry,
wound
dressings,
tissue
engineering
discussed.
While
significant
been
achieved,
challenges
prospects
optimizing
synthesis,
improving
mechanical
properties,
exploring
new
functionalities
Overall,
this
highlights
remarkable
class
biomaterials
with
immense
biomedical,
pharmaceutical,
materials
science
fields.