
Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown
Published: Nov. 20, 2024
Language: Английский
Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown
Published: Nov. 20, 2024
Language: Английский
RSC Advances, Journal Year: 2025, Volume and Issue: 15(9), P. 6593 - 6633
Published: Jan. 1, 2025
(a) Anodic B@LGTs and (b) cathodic BBR electronic flow through thinly adhered water dipoles with robust FRET for PCR supported (c) zero UV absorbance, (d) recycling wastewater via photocatalysis (e) extended morphology from LSNRs to B@LGTs.
Language: Английский
Citations
1Journal of Separation Science, Journal Year: 2025, Volume and Issue: 48(1)
Published: Jan. 1, 2025
ABSTRACT A comprehensive strategy, including spectroscopic, molecular simulation, proteomics, and bioinformatics techniques, was employed to investigate a novel triazole, 5‐(4‐methoxyphenyl)‐1‐phenyl‐1H‐1,2,3‐triazole, its interactions with high‐abundance blood proteins, identification of low‐abundance proteins. The binding constants thermodynamic parameters the triazole two globular human serum albumin, immunoglobulin G (HIgG), were obtained by spectroscopic techniques computational chemistry. two‐dimensional gel electrophoresis in combination matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry isolate identify differentially expressed proteins samples following exposure triazole. results indicated that there is strong albumin/HIgG hydrophobic interaction plays main role system. There 21 highly identified from intervened By analysis, one differential kininogen‐1 protein, explore mechanism action 5‐(4‐methoxyphenyl)‐1‐phenyl‐1H‐1,2,3‐triazole intervention on kallikrein–kinin signaling pathways related HeLa cervical cancer cells. displayed antiproliferative activity significantly altered kallikrein‐10 expression, suggesting possible antitumor involving These research findings provide scientific insights for further development application 1,2,3‐triazole compound. study highlights potential compound as multifunctional pharmaceutical agent, particularly therapies, lays foundation future clinical applications targeting drug–protein interactions.
Language: Английский
Citations
0Journal of Molecular Liquids, Journal Year: 2025, Volume and Issue: unknown, P. 127130 - 127130
Published: Feb. 1, 2025
Language: Английский
Citations
0Journal of Molecular Liquids, Journal Year: 2025, Volume and Issue: unknown, P. 127176 - 127176
Published: Feb. 1, 2025
Language: Английский
Citations
0Polymer Bulletin, Journal Year: 2025, Volume and Issue: unknown
Published: May 8, 2025
Language: Английский
Citations
0Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown
Published: Nov. 20, 2024
Language: Английский
Citations
0