Heliyon,
Journal Year:
2023,
Volume and Issue:
9(8), P. e19230 - e19230
Published: Aug. 1, 2023
Developing
and
designing
efficient
wound
dressings
have
gained
increasing
attention
shown
beneficial
results
in
improved
healing
effects.
This
study
was
conducted
to
improve
properties
introduce
a
novel
potential
dressing.
A
hydrogel
based
on
polyvinylpyrrolidone/poly
acrylic
acid
containing
Zinc
oxide
nanoparticles
prepared
as
an
antibacterial
dressing
examined
rat
excisional
model.
by
free
radical
polymerization
using
potassium
persulfate
(KPS)
initiator,
N,
N-methylene
bisacrylamide
(MBA)
cross-linker,
poly
(PAA)
monomer
the
presence
of
polyvinylpyrrolidone
(PVP)
(ZnO
NPs).
Analyses
such
Scanning
Electron
Microscope
(SEM),
Fourier-transform
infrared
spectroscopy
(FTIR),
X-ray
diffraction
analysis
(XRD),
Thermal
gravimetric
(TGA)
were
used
morphology
structure.
After
choosing
optimal
sample,
vivo
characterization
injury
model
done.
The
rate
histological
calculated
compared
among
groups.
therapeutic
PAA-PVP-ZnO-%2
investigated
control
group.
Results
showed
that
polyacrylic
acid/polyvinylpyrrolidone
zinc
accelerated
contraction,
had
effects,
promoted
other
Gels,
Journal Year:
2023,
Volume and Issue:
9(2), P. 138 - 138
Published: Feb. 6, 2023
Wound
healing
is
a
long-term
and
complex
biological
process
that
involves
multiple
hemostasis,
inflammation,
proliferation,
remodeling
stages.
In
order
to
realize
comprehensive
systematic
wound
management,
appropriate
treatment
bio-adhesives
are
urgently
needed.
Hydrogel
have
excellent
properties
show
unique
remarkable
advantages
in
the
field
of
management.
This
review
begins
with
detailed
description
design
criteria
functionalities
ideal
hydrogel
for
healing.
Then,
recent
advances
polysaccharide-based
multifunctional
bio-adhesives,
which
involve
chitosan,
hyaluronic
acid,
alginate,
cellulose,
dextran,
konjac
glucomannan,
chondroitin
sulfate,
other
polysaccharides,
comprehensively
discussed.
Finally,
current
challenges
future
research
directions
proposed
stimulate
further
exploration
by
researchers.
Advanced Industrial and Engineering Polymer Research,
Journal Year:
2023,
Volume and Issue:
7(1), P. 79 - 99
Published: July 19, 2023
Chitosan
is
obtained
from
chitin,
which
abundantly
found
in
crustaceans
and
through
various
methods.
The
demineralization,
deproteinization,
discoloration,
deacetylation
of
chitin
produce
chitosan
consisting
D-glucosamine
N-acetyl
units
that
are
linked
β-(1,4)-glycosidic
linkages.
has
gained
significant
attention
the
biomedical
field
due
to
its
unique
properties
such
as
abundance,
renewability,
non-toxic
nature,
antimicrobial
activity,
biodegradability,
polyfunctionality.
One
key
why
it
been
heavily
utilized
field.
To
provide
a
comprehensive
overview
chitosan,
this
review
discusses
extraction
based
on
source
It
also
delves
into
chemical
modifications
nanocomposite
development
using
natural
synthetic
materials.
emphasizes
multitude
make
an
excellent
choice
for
wide
range
applications.
mechanisms
antibacterial
activity
factors
affecting
activity.
Additionally,
highlights
hemocompatibility,
antioxidant
anti-inflammation,
other
contribute
suitability
different
applications,
including
wound
dressing
materials,
drug
delivery
carriers,
biosensing
diagnostic
devices,
bone
substitutes,
bioimaging.
While
discussing
some
limitations
concludes
with
future
perspective
developing
multifunctional
chitosan-based
nanomaterials
could
potentially
move
laboratory
clinical
trials
treating
diseases.
Gels,
Journal Year:
2024,
Volume and Issue:
10(1), P. 43 - 43
Published: Jan. 5, 2024
The
care
and
rehabilitation
of
acute
chronic
wounds
have
a
significant
social
economic
impact
on
patients
global
health.
This
burden
is
primarily
due
to
the
adverse
effects
infections,
prolonged
recovery,
associated
treatment
costs.
Chronic
can
be
treated
with
variety
approaches,
which
include
surgery,
negative
pressure
wound
therapy,
dressings,
hyperbaric
oxygen
therapy.
However,
each
these
strategies
has
an
array
limitations.
existing
dry
dressings
lack
functionality
in
promoting
healing
exacerbating
pain
by
adhering
wound.
Hydrogels,
are
commonly
polymer-based
swell
water,
been
proposed
as
potential
remedies
their
ability
provide
moist
environment
that
facilitates
healing.
Their
unique
composition
enables
them
absorb
exudates,
exhibit
shape
adaptability,
modified
incorporate
active
compounds
such
growth
factors
antibacterial
compounds.
review
provides
updated
discussion
leading
natural
synthetic
hydrogels
utilized
healing,
details
latest
advancements
hydrogel
technology,
explores
alternate
approaches
this
field.
Search
engines
Scopus,
PubMed,
Science
Direct,
Web
were
advances
applications
over
last
fifteen
years.
