International Journal of Dairy Technology,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 10, 2024
Lactiplantibacillus
plantarum
M660
(M660)
was
isolated
from
the
human
milk
of
a
healthy
mother.
could
survive
simulated
gastrointestinal
conditions
without
haemolytic
and
biogenic
amine‐producing
ability.
The
faecal
water
content
reduced,
recoveries
cecum
intestinal
barrier
were
accelerated
by
in
antibiotic‐associated
diarrhoea
model.
In
constipation
model,
enhanced
motility,
improved
serum
neurotransmitter
levels,
reduced
colonic
injury.
Analysis
gut
microbiota
showed
that
increased
abundance
potentially
beneficial
bacteria
decreased
number
pathogenic
bacteria.
Overall,
be
probiotic
candidate
to
promote
infant
health.
Plants,
Journal Year:
2024,
Volume and Issue:
13(13), P. 1721 - 1721
Published: June 21, 2024
Plants
are
a
core
part
of
cultural
identity,
as
diet,
decorations,
ceremonies,
or
medicinal
agents.
Empirical
knowledge
regarding
plants
and
their
healing
potential
has
existed
worldwide
for
centuries.
With
the
advance
science
technology,
not
only
is
refinement
such
sources
isolation
specific
compounds
possible,
but
these
can
also
be
characterized
based
on
natural
occurrence.
Besides
importance
plant
metabolism
structure,
polysaccharides
have
been
demonstrated
to
substantial
positive
human
health
impacts
inflammation,
metabolism,
oxidative
stress,
others.
As
an
inherent
cell
walls,
many
from
herbs,
fructans,
glucans,
pectins,
extracted
analyzed
structure
function.
However,
review
summarizing
significant
portion
studies
was
still
unavailable.
This
helps
fill
gap
between
polysaccharide
bioactivity,
matrix
sources,
focusing
historical
usage.
Research Square (Research Square),
Journal Year:
2024,
Volume and Issue:
unknown
Published: June 26, 2024
Abstract
This
article
conducted
research
and
analysis
on
the
relationship
between
cisplatin
induced
intestinal
barrier
disruption,
gut
microbiota
imbalance,
protect
effect
of
chlorogenic
acid
(CGA)
gastro
intestine.
selected
C57BL/6J
mice
as
object,
with
an
age
4
weeks
a
total
28
mice.
The
were
divided
into
groups,
including
control
group
(CN),
(Cis)
group,
CGA
treatment
receiving
intraperitoneal
injections
alongside
(Cis
+
CGA1),
last
pre-treated
before
administration
CGA2).
study
used
RT
qPCR
to
determine
IL-6,
IL-1β
TNF-ɑ
mRNA,
while
serum
levels
these
cytokines
fecal
LPS
determined
through
ELISA.
Western
blot
was
analyze
expression
Occludin
ZO-1
proteins
in
colon
tissue,
H&E
staining
histopathological
conditions
tissue.
Moreover,
this
also
utilized
high-throughput
sequencing
feces.
results
indicated
that
reduced
TNF-α
level
both
tissue
compared
Cis
group.
pretreatment
notably
enhanced
tissues,
improved
integrity.
Histopathological
confirmed
reduction
inflammation
injury
treatment.
16S
rDNA
showed
Bacteroidetes
Firmicutes
predominated
saw
rise
Proteobacteria,
notable
shift
microbiota's
composition
decrease
α
diversity.
able
mitigate
changes
by
cisplatin.
All
suggest
effectively
mitigates
inflammatory
response
destruction
mucosal
intestines
caused
cisplatin,
offering
protective
against
disturbances
flora.
International Journal of Dairy Technology,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Dec. 10, 2024
Lactiplantibacillus
plantarum
M660
(M660)
was
isolated
from
the
human
milk
of
a
healthy
mother.
could
survive
simulated
gastrointestinal
conditions
without
haemolytic
and
biogenic
amine‐producing
ability.
The
faecal
water
content
reduced,
recoveries
cecum
intestinal
barrier
were
accelerated
by
in
antibiotic‐associated
diarrhoea
model.
In
constipation
model,
enhanced
motility,
improved
serum
neurotransmitter
levels,
reduced
colonic
injury.
Analysis
gut
microbiota
showed
that
increased
abundance
potentially
beneficial
bacteria
decreased
number
pathogenic
bacteria.
Overall,
be
probiotic
candidate
to
promote
infant
health.
