Anti-atherosclerotic effects of natural compounds targeting lipid metabolism and inflammation: focus on PPARs, LXRs, and PCSK9 DOI Creative Commons
Marcella Palumbo, M. Ugolotti, Francesca Zimetti

et al.

Atherosclerosis Plus, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 1, 2024

A large body of evidence has shown that modulation the nuclear receptors peroxisome proliferator-activated (PPARs), liver X (LXRs), proprotein convertase subtilisin/kexin type 9 (PCSK9) and inflammatory processes by natural compounds hypolipidemic anti-atherosclerotic effects. These beneficial outcomes are certainly related to crucial function these targets in maintaining cholesterol homeostasis regulating systemic inflammation. Currently, therapeutic scenario for cardiovascular diseases (CVD) offers a plethora widely validated functional pharmacological treatments improve health status patients. However, patients increasingly sceptical which often associated with moderate severe side The aim our review is provide collection most recent scientific on common phytochemicals, used centuries Mediterranean diet traditional chinese medicine act key regulators inflammation, could constitute important tools CVD management.

Language: Английский

Cajaninstilbene Acid and Its Derivative as Multi-Therapeutic Agents: A Comprehensive Review DOI Creative Commons

Wen Hou,

Lejun Huang,

Jinyang Wang

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(22), P. 5440 - 5440

Published: Nov. 18, 2024

Pigeon pea (

Language: Английский

Citations

0
Anti-atherosclerotic effects of natural compounds targeting lipid metabolism and inflammation: focus on PPARs, LXRs, and PCSK9 DOI Creative Commons
Marcella Palumbo, M. Ugolotti, Francesca Zimetti

et al.

Atherosclerosis Plus, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 1, 2024

A large body of evidence has shown that modulation the nuclear receptors peroxisome proliferator-activated (PPARs), liver X (LXRs), proprotein convertase subtilisin/kexin type 9 (PCSK9) and inflammatory processes by natural compounds hypolipidemic anti-atherosclerotic effects. These beneficial outcomes are certainly related to crucial function these targets in maintaining cholesterol homeostasis regulating systemic inflammation. Currently, therapeutic scenario for cardiovascular diseases (CVD) offers a plethora widely validated functional pharmacological treatments improve health status patients. However, patients increasingly sceptical which often associated with moderate severe side The aim our review is provide collection most recent scientific on common phytochemicals, used centuries Mediterranean diet traditional chinese medicine act key regulators inflammation, could constitute important tools CVD management.

Language: Английский

Citations

0