Natural Products: Harnessing the Power of Gut Microbiota for Neurological Health DOI
Hao Cheng, Juan Liu, Dandan Zhang

et al.

Phytomedicine, Journal Year: 2024, Volume and Issue: unknown, P. 156019 - 156019

Published: Sept. 1, 2024

Language: Английский

Folate and Its Significance in Depressive Disorders and Suicidality: A Comprehensive Narrative Review DOI Open Access
Timur Liwinski, Undine E. Lang

Nutrients, Journal Year: 2023, Volume and Issue: 15(17), P. 3859 - 3859

Published: Sept. 4, 2023

Depressive disorders pose significant challenges to global public health, necessitating effective prevention and management strategies. Notably, the occurrence of suicide frequently coincides with depressive episodes. Suicide is as a paramount health concern that demands efficacious preventive Current psychiatric approaches heavily rely on pharmacological interventions but have had limited success in addressing burden mental issues. Suboptimal nutrition, its impact neuroendocrine system, has been implicated underlying pathology disorders. Folate, group water-soluble compounds, plays crucial role various central nervous system functions. Depressed individuals often exhibit low levels serum red blood cell folate. Multiple studies systematic reviews investigated efficacy folic acid derivative, L-methylfolate, which can cross blood–brain barrier, stand-alone or adjunct therapies for depression. Although findings mixed, available evidence generally supports use these compounds depressed individuals. Recent established links between one-carbon cycle, folate–homocysteine balance, immune function, glutamate excitation via NMDA (N-methyl-D-aspartate) receptors, gut microbiome eubiosis mood regulation. These provide insights into complex neurobiological mechanisms effects folate related Through comprehensive review existing literature, this study aims advance our understanding therapeutic potential depression treatment. It also seeks explore their suicidal tendencies shed light involved, leveraging latest discoveries research.

Language: Английский

Citations

29
Antitumor immunostimulatory activity of the traditional Chinese medicine polysaccharide on hepatocellular carcinoma DOI Creative Commons
Yang Liu,

Jiawen Wu,

Huiqin Hao

et al.

Frontiers in Immunology, Journal Year: 2024, Volume and Issue: 15

Published: Feb. 22, 2024

Hepatocellular carcinoma (HCC) is a prevalent malignancy, often associated with compromised immune function in affected patients. This can be attributed to the secretion of specific factors by liver cancer cells, which hinder response and lead state suppression. Polysaccharides derived from traditional Chinese medicine (TCM) are valuable constituents known for their immunomodulatory properties. review aims look into effects TCM polysaccharides on HCC. The primarily manifested through activation effector T lymphocytes, dendritic NK macrophages against hepatocellular both vivo vitro settings. Furthermore, have demonstrated remarkable adjuvant antitumor HCC clinical Therefore, utilization holds promising potential development novel therapeutic agents or adjuvants advantageous properties

Language: Английский

Citations

11
Polysaccharides from Cistanche deserticola mitigate inflammatory bowel disease via modulating intestinal microbiota and SRC/EGFR/PI3K/AKT signaling pathways DOI
Ming Qiao,

Taotao Xue,

Yi Zhu

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 142452 - 142452

Published: March 1, 2025

Language: Английский

Citations

2
Fermented Gracilaria lemaneiformis polysaccharides alleviate food allergy by regulating Treg cells and gut microbiota DOI
Huiying Chen, Yuchen Zhou, Yan Liu

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 269, P. 132215 - 132215

Published: May 9, 2024

Language: Английский

Citations

9
Along the microbiota–gut–brain axis: Use of plant polysaccharides to improve mental disorders DOI
Jiayu Gao, Ying Liang, Pu Liu

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 265, P. 130903 - 130903

Published: March 19, 2024

Language: Английский

Citations

8
Cistanche deserticola polysaccharides enhance female germline stem cell differentiation through BMP/SMAD signaling to mitigate premature ovarian failure DOI
Yikai Qiu, Jinhua Li, Yanping Zhang

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 140848 - 140848

Published: Feb. 1, 2025

Language: Английский

Citations

1
Cistanche deserticola polysaccharide- functionalized dendritic fibrous nano-silica −based adjuvant for H9N2 oral vaccine enhance systemic and mucosal immunity in chickens DOI
Jin He,

Xuanqi Lu,

Ningning Mao

et al.

International Journal of Pharmaceutics, Journal Year: 2024, Volume and Issue: 660, P. 124318 - 124318

Published: June 7, 2024

Language: Английский

Citations

5
Exploratory studies of the antidepressant effect of Cordyceps sinensis polysaccharide and its potential mechanism DOI

Xingfang Zhang,

Yajun Qiao, Guoqiang Li

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 277, P. 134281 - 134281

Published: July 29, 2024

Language: Английский

Citations

4
Advance in Cistanche deserticola Y. C. Ma. polysaccharides: Isolation, structural characterization, bioactivities and application: A review DOI

Taotao Xue,

Dong‐Xuan Zheng,

Limei Wen

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 278, P. 134786 - 134786

Published: Aug. 15, 2024

Language: Английский

Citations

4
Medicinal and food plant: Cistanches Herba, a potential therapeutic hope for Parkinson’s disease and related complications DOI Creative Commons
Guoxue Zhu, Chengcheng Xu, Shujun Jiang

et al.

Journal of Agriculture and Food Research, Journal Year: 2025, Volume and Issue: unknown, P. 101671 - 101671

Published: Jan. 1, 2025

Language: Английский

Citations

0