Advances in chitosan-based blends as potential drug delivery systems: A review

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 273, P. 132916 - 132916

Published: June 5, 2024

Language: Английский

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Shape-memory and self-healing properties of sustainable cellulosic nanofibers-based hybrid materials for novel applications

Giant, Journal Year: 2024, Volume and Issue: 19, P. 100299 - 100299

Published: June 5, 2024

In the era of smart and sustainable technology driven by naturally occurring materials, various nanocellulose-based materials play a crucial role. Shape memory behaviour self-healing capabilities nanocelluloses are emerging as focal points in numerous research domains. Nanocellulose its derivatives such cellulose nanocrystals (CNC) nanofibers (CNF), currently limelight due to their excellent shape-memory properties, making them suitable for multifunctional devices. this regard, CNF, cutting-edge material, has spurred researchers explore potential developing contemporary personalized health Therefore, timely comprehensive review is essential gain deep insights into effectiveness CNF Herein, we first provide succinct introduction all nanocellulose materials. This also depicts recent advancements breakthroughs large effective synthesis CNF-based hybrid Next, focusing on performance, sheds new light advanced applications Finally, perspectives current challenges opportunities field summarized future an in-depth understanding "CNF-based materials."

Language: Английский

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Chitosan-Based Schiff Bases (CSBs) and Their Metal Complexes: Promising Antimicrobial Agents

Molecules, Journal Year: 2025, Volume and Issue: 30(2), P. 207 - 207

Published: Jan. 7, 2025

The scientific interest in the chemical modification of chitosan to increase its solubility and application has led conjugation with Schiff bases, which are interesting scaffolds endowed diverse biological properties. resultant chitosan-based bases (CSBs) widely studied literature due myriad activities exerted, both catalytic biological, including anticancer, anti-inflammatory, antioxidant, especially antimicrobial ones. Antimicrobial resistance (AMR) is one major public health challenges twenty-first century because it represents a threat prevention treatment growing number bacterial, parasitic, viral, fungal infections that no longer treatable available drugs. Thus, this review, we present brief outline CSBs as well their complexes metals, particular focus on recent regarding effect these captivating derivatives.

Language: Английский

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A review of DNA nanoparticles-encapsulated drug/gene/protein for advanced controlled drug release: Current status and future perspective over emerging therapy approaches

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 268, P. 131694 - 131694

Published: April 18, 2024

Language: Английский

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A review of carboxymethyl cellulose composite-based hydrogels in drug delivery applications

Results in Chemistry, Journal Year: 2024, Volume and Issue: 10, P. 101695 - 101695

Published: July 31, 2024

The use of naturally occurring biopolymers in the drug delivery applications have attracted significant attention due to their biocompatibility, biodegradability, and non-toxicity. Over years, carboxymethyl cellulose, a natural polymer has emerged as good candidate its molecular-binding gel-forming properties. This review study comprehensively explores CMC composites-based hydrogels efficient systems. Various synthesized using with additives such tamarind gum, xanthun gelatin, graphene oxide, polyacrylamide, chitosan etc. are discussed terms this study. Specific examples drugs involve acyclovir, 5-fluorouracil, doxorubicin, curcumin. novelty lies comprehensive evaluation cellulose composite-based hydrogels, highlighting potential enhance efficacy, pH sensitive, targeted release, offering biocompatible, biodegradable, non-toxic alternative synthetic polymers for applications.

Language: Английский

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Amphiphilic nanofibrillated cellulose/polyurethane composites with antibacterial, antifouling and self-healing properties for potential catheter applications

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 263, P. 130407 - 130407

Published: Feb. 27, 2024

Language: Английский

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Polysaccharide-Based Composite Systems in Bone Tissue Engineering: A Review

Materials, Journal Year: 2024, Volume and Issue: 17(17), P. 4220 - 4220

Published: Aug. 27, 2024

In recent years, a growing demand for biomaterials has been observed, particularly applications in bone regenerative medicine. Bone tissue engineering (BTE) aims to develop innovative materials and strategies repairing regenerating defects injuries. Polysaccharides, due their biocompatibility, biodegradability as well bioactivity, have emerged promising candidates scaffolds or composite systems BTE. Polymers combined with bioactive ceramics can support osteointegration. Calcium phosphate (CaP) be broad choice an inorganic phase that stimulates the formation of new apatite layers. This review provides comprehensive analysis based on selected polysaccharides used engineering, highlighting synthesis, properties applications. Moreover, applicability produced biocomposites analyzed, trends modifying endowing them functionalizations. The effects these composites mechanical properties, biocompatibility osteoconductivity were critically analyzed. article summarizes latest manufacturing methods developments polysaccharide-based cartilage regeneration

Language: Английский

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Cellulose-based hydrogels enhanced with bioactive molecules for optimal chronic diabetic wound management

Journal of Microencapsulation, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 24

Published: March 23, 2025

Hydrogels are three-dimensional structures that replicate natural tissues' extracellular matrix (ECM). They essential for transporting exudates, gases, and moisture facilitating cellular interactions in tissue engineering wound healing. The choice of primary material designing the scaffold is necessary to be paid more attention rather than common sources, including plant fibres like cotton, bamboo, algae, as well bacterial marine-derived materials. Among them, cellulose-based polymers especially valued their biocompatibility ability promote Chronic diabetic wounds pose unique treatment challenges, such necrosis infection risks. Consequently, a growing interest incorporating bioactive molecules into hydrogels. This article investigates how these infused hydrogels enhance healing process chronic wounds, examining various loading crosslinking techniques alongside clinical applications. It also discusses benefits limitations with improve strategies.

Language: Английский

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Antimicrobial Biomaterial for Dental Healthcare Application

Published: Jan. 1, 2025

Language: Английский

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Chitin, Chitosan and Its Derivatives: Antimicrobials and/or Mitigators of Water

Macromol—A Journal of Macromolecular Research, Journal Year: 2025, Volume and Issue: 5(2), P. 15 - 15

Published: April 8, 2025

Antimicrobial resistance (AMR) is a major global health problem, exacerbated by the excessive and inappropriate use of antibiotics in human medicine, animal care agriculture. Therefore, new strategies compounds are needed to overcome this issue. In view, it may be appropriate reconsider existing biomaterials alleviate antibiotic overuse. Chitin, naturally abundant amino mucopolysaccharide, poly-β-1, 4-N-acetylglucosamine (GlcNAc). It white, hard, inelastic, nitrogenous polysaccharide source surface pollution coastal areas. Chitosan derives from partial N-deacetylation chitin originates shells crustaceans fungi cell walls. nontoxic natural antimicrobial polymer approved GRAS (Generally Recognized as Safe United States Food Drug Administration). Chitin chitosan, non-toxic biopolymers, useful for wastewater treatment remove pollutants, such pharmaceuticals, heavy metals dyes. The described features make these biopolymers intriguing investigated their application antibacterials.

Language: Английский

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