From Sea to Cell: Marine Peptides as Key Players in siRNA-Mediated Cancer Therapy DOI
Ricky Indra Alfaray, Nurlinah Amalia,

M. Ali

et al.

Interdisciplinary cancer research, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

Language: Английский

Functional biomass/biological macromolecular phase change composites and their applications in different scenarios: A review DOI Creative Commons
Yang Cao, Jingtao Su,

Yongshuang Xiao

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 141377 - 141377

Published: Feb. 1, 2025

Language: Английский

Citations

4

Methyl 3-Bromo-4,5-dihydroxybenzoate Attenuates Inflammatory Bowel Disease by Regulating TLR/NF-κB Pathways DOI Creative Commons
Jing Huang, Lei Li,

Liyan Xu

et al.

Marine Drugs, Journal Year: 2025, Volume and Issue: 23(1), P. 47 - 47

Published: Jan. 19, 2025

Inflammatory bowel disease (IBD) is characterized by uncontrolled, chronic relapsing inflammation in the gastrointestinal tract and has become a global healthcare problem. Here, we aimed to illustrate anti-inflammatory activity underlying mechanism of methyl 3-bromo-4,5-dihydroxybenzoate (MBD), compound derived from marine organisms, especially IBD, using zebrafish model. The results indicated that MBD could inhibit inflammatory responses induced CuSO4, tail amputation LPS zebrafish. Furthermore, notably inhibited intestinal migration immune cells, enhanced integrity gut mucosal barrier improved peristalsis function IBD model trinitro-benzene-sulfonic acid (TNBS). In addition, ROS elevation TNBS. Network pharmacology analysis, molecular docking, transcriptomics sequencing RT-PCR were conducted investigate potential mechanism. showed regulate TLR/NF-κB pathways inhibiting mRNA expression TNF-α, NF-κB, IL-1, IL-1β, IL6, AP1, IFNγ, IKKβ, MyD88, STAT3, TRAF1, TRAF6, NLRP3, NOD2, TLR3 TLR4, promoting IL4, IκBα Bcl-2. conclusion, these findings indicate be candidate for treatment IBD.

Language: Английский

Citations

0

A chitosan-based deep tumor-penetrating nano-photothermal agent for enhanced chemo-photothermal combination therapy DOI
Fangying Zheng, Tan Ding, Yilin Zheng

et al.

Materials Today Chemistry, Journal Year: 2025, Volume and Issue: 45, P. 102676 - 102676

Published: April 1, 2025

Language: Английский

Citations

0

Marine-based bioactive self-healing hydrogel with tunable properties for tissue engineering and regenerative medicine DOI

B. Karuppasamy,

Nimu Chand Reger, Shanmugam Munisamy

et al.

Journal of Drug Delivery Science and Technology, Journal Year: 2024, Volume and Issue: 101, P. 106267 - 106267

Published: Oct. 8, 2024

Language: Английский

Citations

2

Sustainable valorisation of seafood-derived proteins: current approaches for recovery and applications in biomedical and food systems DOI
Slim Smaoui, Elahesadat Hosseini, Zenebe Tadesse Tsegay

et al.

Food Bioscience, Journal Year: 2024, Volume and Issue: 62, P. 105450 - 105450

Published: Nov. 12, 2024

Language: Английский

Citations

1

Materials with Marine Origins for Cancer Therapy DOI
Joana Silva, Alice Martins, Patrícia Susano

et al.

Springer eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 23

Published: Jan. 1, 2024

Language: Английский

Citations

0

Materials with Marine Origins for Cancer Therapy DOI
Joana Silva, Alice Martins, Patrícia Susano

et al.

Springer eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 1231 - 1253

Published: Jan. 1, 2024

Language: Английский

Citations

0

From Sea to Cell: Marine Peptides as Key Players in siRNA-Mediated Cancer Therapy DOI
Ricky Indra Alfaray, Nurlinah Amalia,

M. Ali

et al.

Interdisciplinary cancer research, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

Language: Английский

Citations

0