Animals,
Journal Year:
2024,
Volume and Issue:
14(24), P. 3705 - 3705
Published: Dec. 22, 2024
The
adult
male
muskrat
has
a
pair
of
scented
glands,
which
show
clear
seasonal
changes
in
their
developmental
status
between
the
secretion
season
and
non-secretion
season.
During
season,
glands
are
much
larger
than
with
metabolism
glandular
cells
increasing
large
amount
musk
being
produced.
In
this
work,
blood,
musk,
gland
tissue
were
collected
from
three
healthy
muskrats
during
(September).
And
blood
another
(November)
also
sampled.
saccharides
detected
by
liquid
chromatography–mass
spectrometry
(LC-MS),
indicating
concentrated
What
is
more,
transcriptome
analysis
was
employed
to
investigate
expression
patterns
saccharides’
pathways,
suggesting
some
metabolism-related
genes
undergo
significant
changes.
Above
all,
displays
differences,
enhancement
metabolic
activity
phase
maintains
proliferation
function.
Abstract
Recent
advances
in
understanding
the
modulatory
functions
of
gut
and
microbiota
on
human
diseases
facilitated
our
focused
attention
contribution
to
pathophysiological
alterations
many
extraintestinal
organs,
including
liver,
heart,
brain,
lungs,
kidneys,
bone,
skin,
reproductive,
endocrine
systems.
In
this
review,
we
applied
“gut–X
axis”
concept
describe
linkages
between
other
organs
discussed
latest
findings
related
axis,”
underlying
mechanisms
potential
clinical
intervention
strategies.
Foods,
Journal Year:
2024,
Volume and Issue:
13(5), P. 721 - 721
Published: Feb. 27, 2024
The
daylily
(Hemerocallis
citrina
Baroni)
flower
is
a
traditional
raw
food
material
that
rich
in
variety
of
nutrients.
In
particular,
the
content
polysaccharides
abundant
and
has
been
widely
used
as
functional
component
food,
cosmetics,
medicine,
other
industries.
However,
studies
on
structure-effective
relationship
are
still
lacking.
view
this,
were
isolated
purified,
their
physical
chemical
properties,
structure,
antioxidant
activity,
adhesion-promoting
effect
probiotics
evaluated.
results
showed
novel
water-soluble
polysaccharide
(DPW)
with
an
average
molecular
weight
(Mw)
2.224
kDa
could
be
successfully
using
column
chromatography.
Monosaccharide
composition
analysis
DPW
only
comprised
glucose
fructose,
molar
ratio
0.242:0.758.
Through
methylation
nuclear
magnetic
resonance
(NMR)
analysis,
it
was
inferred
belonged
to
fructans
group
structure
α-D-Glcp-1→2-β-D-Fruf-1→(2-β-D-Fruf-1)n→.
Antioxidant
strong
2-Phenyl-4,4,5,5-tetramethylimidazoline-1-oxyl-3-Oxide
(PTIO-scavenging
activity
IC50
1.54
mg/mL.
1.25
5
mg/mL
significantly
increase
adhesion
rate
Lactobacillus
acidophilu,
casei,
Bifidobacterium
adolescentis,
plantarum
Caco-2
cells.
Considering
above
results,
present
study
provides
theoretical
basis
practical
support
for
development
application
active
ingredient.
Foods,
Journal Year:
2024,
Volume and Issue:
13(23), P. 3882 - 3882
Published: Nov. 30, 2024
Natural
plant
polysaccharides
are
renowned
for
their
broad
spectrum
of
biological
activities,
making
them
invaluable
in
both
the
pharmaceutical
and
food
industries.
Their
safety,
characterized
by
low
toxicity
minimal
side
effects,
coupled
with
potential
therapeutic
properties,
positions
as
crucial
elements
health-related
applications.
The
functional
effectiveness
these
is
deeply
connected
to
structural
attributes,
including
molecular
weight,
monosaccharide
components,
types
glycosidic
bonds.
These
influence
how
interact
gut
microbiota,
potentially
alleviating
various
metabolic
inflammatory
disorders
such
bowel
disease,
diabetes,
liver-associated
pathologies,
obesity,
kidney
diseases.
operate
through
a
range
mechanisms.
They
enhance
formation
short-chain
fatty
acids,
which
pivotal
keeping
intestinal
health
balance.
Additionally,
they
strengthen
mucosal
barrier,
deterring
ingress
pathogens
toxins
into
host
system.
By
modulating
immune
responses
within
gut,
help
managing
immune-mediated
disorders,
role
activating
specific
cellular
signaling
pathways
further
underscores
potential.
review
delves
intricate
structure-activity
relationships
natural
interactions
flora.
understanding
relationships,
scientific
community
can
develop
targeted
strategies
use
therapeutics,
leading
innovative
treatments
Furthermore,
insights
gained
drive
advancement
research
polysaccharide
applications,
providing
direction
novel
dietary
supplements
foods
designed
support
overall
well-being.
Advanced Functional Materials,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 10, 2025
Abstract
Bone
fractures,
especially
large
and
complex
defects,
continue
to
pose
significant
challenges
in
the
medical
field.
Current
treatments
often
rely
on
autografts
or
allografts
for
structural
support,
which
can
lead
problems
such
as
reduced
bioactivity,
infection
risks,
potential
pathogen
transmission.
Nature
herbal
medicine
(NHM),
including
herbs
extracts,
offers
a
promising
alternative
by
effectively
modulating
inflammatory
responses,
enhancing
osteoblast
function,
inhibiting
bone
resorption,
thereby
facilitating
fracture
repair.
However,
traditional
drug
delivery
methods
NHM
encounter
interactions,
poor
tissue
distribution,
patient
compliance.
Biomaterials,
engineered
interact
with
biological
systems,
play
essential
roles
repair,
mechanical
delivery.
When
used
carriers,
biomaterials
be
combined
form
stable
systems
that
further
promote
regeneration.
Here
applications
of
are
reviewed,
hydrogels,
extracellular
vesicles,
cement,
conjunction
regulating
homeostasis
aiming
provide
valuable
insights
guidance
future
research
therapeutic
strategies.
