Alginate/bacterial cellulose/GelMA scaffolds with aligned nanopatterns and hollow channel networks for vascularized bone repair
International Journal of Biological Macromolecules,
Journal Year:
2025,
Volume and Issue:
unknown, P. 142578 - 142578
Published: March 1, 2025
Language: Английский
Effects of Nanomaterials on Synthesis and Degradation of the Extracellular Matrix
Zhiyan Zhou,
No information about this author
Yanli Zhang,
No information about this author
Yuting Zeng
No information about this author
et al.
ACS Nano,
Journal Year:
2024,
Volume and Issue:
18(11), P. 7688 - 7710
Published: March 4, 2024
Extracellular
matrix
(ECM)
remodeling
is
accompanied
by
the
continuous
synthesis
and
degradation
of
ECM
components.
This
dynamic
process
plays
an
important
role
in
guiding
cell
adhesion,
migration,
proliferation,
differentiation,
as
well
tissue
development,
body
repair,
maintenance
homeostasis.
Nanomaterials,
due
to
their
photoelectric
catalytic
properties
special
structure,
have
garnered
much
attention
biomedical
fields
for
use
processes
such
engineering
disease
treatment.
Nanomaterials
can
reshape
microenvironment
changing
ECM-related
proteins,
thereby
indirectly
behavior
surrounding
cells.
review
focuses
on
regulatory
nanomaterials
different
proteins
extracellular
protease.
We
discuss
influencing
factors
possible
related
mechanisms
remodeling,
which
may
provide
insights
into
design
development
treatment
disorder-related
diseases.
Language: Английский
Mesenchymal stem cell-derived extracellular vesicles: A promising therapeutic strategy in diabetic osteoporosis
Yajing Yang,
No information about this author
Xi-Er Chen,
No information about this author
Xuchang Zhou
No information about this author
et al.
World Journal of Diabetes,
Journal Year:
2024,
Volume and Issue:
15(12), P. 2399 - 2403
Published: Nov. 14, 2024
Diabetic
osteoporosis
(DOP)
is
a
serious
complication
of
diabetes
mellitus.
It
urgent
to
explore
efficient
clinical
treatment
strategies
for
DOP.
has
been
found
that
mesenchymal
stem
cell-derived
extracellular
vesicles
(MSC-EVs),
as
an
emerging
cell-free
therapy,
show
great
potential
in
DOP
treatment.
MSC-EVs
can
effectively
promote
bone
formation,
inhibit
resorption,
and
modulate
the
inflammatory
microenvironment
by
delivering
cargoes
microRNAs,
long
non-coding
RNAs,
proteins
target
cells,
thereby
ameliorating
loss
However,
there
are
limited
reports
on
with
MSC-EVs.
To
evoke
more
attention
this
strategy,
article
summarised
extant
literature
provide
new
directions
further
research
application
management
Language: Английский