Colloids and Surfaces B Biointerfaces, Journal Year: 2024, Volume and Issue: 247, P. 114453 - 114453
Published: Dec. 10, 2024
Language: Английский
International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 281, P. 136276 - 136276
Published: Oct. 9, 2024
Language: Английский
Citations
8
Journal of Macromolecular Science Part B, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 12
Published: Jan. 9, 2025
Colon cancer is still a significant cause of cancer-related deaths and, therefore, new treatment approaches are required. As naturally derived polysaccharide, Chitosan has become one the most promising materials in polymer-based drug delivery systems because its outstanding biocompatibility, biodegradability, and pH-responsive release. This review explores expanding roles chemical modifications colon therapy, emphasizing relationship between macromolecular interactions structure-property dynamics. Recent progress Chitosan-based nanocarriers, including nanoparticles, nanogels hybrid systems, highlights their potential to overcome multidrug resistance minimize off-target toxicity. These advancements closely aligned with developments precision medicine, incorporating stimuli-responsive components targeted ligands for enhanced efficacy. While preclinical clinical studies yield results, critical challenges such as scalability, reproducibility regulatory compliance remain obstacles translation. emphasizes transformative addressing therapeutic barriers treatment. Looking ahead, future should focus on utilizing cutting-edge technologies, artificial intelligence 3D bioprinting, enhance formulations develop personalized solutions that more effective tailored individual needs.
Language: Английский
Citations
1
International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 136688 - 136688
Published: Oct. 1, 2024
Language: Английский
Citations
5
Materials, Journal Year: 2025, Volume and Issue: 18(2), P. 457 - 457
Published: Jan. 20, 2025
Biopolymers represent a significant class of materials with potential applications in skin care due to their beneficial properties. Resveratrol is natural substance that exhibits range biological activities, including the scavenging free radicals and anti-inflammatory anti-aging effects. In this study, chitosan/konjac glucomannan resveratrol-enriched thin films were prepared. The enrichment biomaterials active ingredients common practice, as it allows desired properties be obtained final product. To characterize films, several analyses performed, infrared spectroscopy, imaging samples by SEM AFM techniques, swelling analysis pH 5.5 7.4, mechanical antioxidant assays, contact angle measurements, determination resveratrol release profile under mimicking conditions. incorporation into matrices resulted modifications chemical structure film morphology. characteristics additives found undergo deterioration. sample containing 10% exhibited higher degree than other films. resveratrol-modified demonstrated notable capacity, reduced angle, enhanced wettability. occurred rapidly initially, maximum 84% 56% released depending on type. Thus, proposed formulations have promising properties, particular good high potential, improved wettability, may serve dressings after further investigation.
Language: Английский
Citations
0
Tissue and Cell, Journal Year: 2025, Volume and Issue: 94, P. 102804 - 102804
Published: Feb. 19, 2025
Language: Английский
Citations
0
Frontiers in Bioengineering and Biotechnology, Journal Year: 2025, Volume and Issue: 13
Published: March 7, 2025
Diabetes is a widespread metabolic disorder that presents considerable challenges in its management. Recent advancements biomaterial research have shed light on innovative approaches for the treatment of diabetes. This review examines role biomaterials diabetes diagnosis and treatment, as well their application managing diabetic wounds. By evaluating recent developments alongside future obstacles, highlights promising potential care, underscoring importance enhancing patient outcomes refining methodologies.
Language: Английский
Citations
0
Advanced Healthcare Materials, Journal Year: 2025, Volume and Issue: unknown
Published: March 30, 2025
Abstract Self‐powered wound dressings are effective in treating chronic wounds because of their low toxicity and convenience. However, current self‐powered rely on the bending movements skin or additional large ultrasonic devices. Herein, a flexible adhesive dressing (FASW) that promotes regeneration through daily sound wave driving without relying external devices is proposed. The FASW consists bioadhesive film (BAF), unidirectional fluorinated conductive (UFCF), liquid metal (LM) interlayer. Benefiting from cross‐linking chitosan, exhibits excellent properties, such as biocompatibility, stretchability, tissue adhesion, recyclability. In vivo experiments show reduced inflammation stimulated hair follicle regeneration. This utilizes previously overlooked natural energies for treatment wounds, thereby enhancing therapeutic effect traditional individuals with movement disorders.
Language: Английский
Citations
0
Carbohydrate Polymers, Journal Year: 2025, Volume and Issue: unknown, P. 123590 - 123590
Published: April 1, 2025
Language: Английский
Citations
0
Colloids and Surfaces A Physicochemical and Engineering Aspects, Journal Year: 2025, Volume and Issue: unknown, P. 137013 - 137013
Published: April 1, 2025
Language: Английский
Citations
0
Carbohydrate Polymers, Journal Year: 2025, Volume and Issue: unknown, P. 123656 - 123656
Published: April 1, 2025
Language: Английский
Citations
0