Colloids and Surfaces B Biointerfaces, Journal Year: 2024, Volume and Issue: 247, P. 114453 - 114453
Published: Dec. 10, 2024
Language: Английский
Russian Chemical Reviews, Journal Year: 2024, Volume and Issue: 93(5), P. RCR5120 - RCR5120
Published: May 1, 2024
Chitosan, a natural and abundant polysaccharide, offers several advantageous properties, such as excellent biocompatibility, biodegradability, antimicrobial activity, making it highly versatile material. However, its extensive application is hindered by insolubility in water most organic solvents, due to numerous intramolecular/intermolecular hydrogen bonds. To overcome this limitation optimize benefits, chitosan often chemically modified enhance utility various industries. Biomedical materials, environmental management, biological papermaking, food preservation, the daily chemical industry are few examples. Modified retains inherent properties of acquires new physicochemical characteristics result introduced functional groups. Hydrophilic modifications typically include carboxylation, phosphorylation, quaternary ammonium modification reactions. The specific applications derivatives depend on grafted This review summarizes reaction conditions, hydrophilic drug delivery serving reference for development use chitosan-based biomaterials. <br>The bibliography includes 128 references.
Language: Английский
Citations
3
International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 281, P. 135779 - 135779
Published: Oct. 17, 2024
Language: Английский
Citations
3
Catalysts, Journal Year: 2024, Volume and Issue: 14(6), P. 371 - 371
Published: June 10, 2024
Chitin and chitosan, abundant biopolymers derived from the shells of crustaceans cell walls fungi, have garnered considerable attention in pharmaceutical circles due to their biocompatibility, biodegradability, versatile properties. Deep eutectic solvents (DESs), emerging green composed mixtures hydrogen bond acceptors donors, offer promising avenues for enhancing solubility functionality chitin chitosan formulations. This review delves into potential utilizing DESs as highlighting efficiency dissolving these polymers, which facilitates production novel drug delivery systems, wound dressings, tissue engineering scaffolds, antimicrobial agents. The distinctive physicochemical properties DESs, including low toxicity, volatility, adaptable solvation power, enable customization chitosan-based materials meet specific requirements. Moreover, environmentally friendly nature aligns with growing demand sustainable eco-friendly processes manufacturing. revision underscores recent advances illustrating role evolving applications laying groundwork development innovative systems biomedical enhanced efficacy safety profiles.
Language: Английский
Citations
2
Cosmetics, Journal Year: 2024, Volume and Issue: 11(4), P. 138 - 138
Published: Aug. 13, 2024
Excessive ultraviolet (UV) exposure can lead to sunburn, characterized by skin barrier damage, inflammation, pain, and an increased risk of cancer. Recombinant collagens have gradually attracted attention due their high purity, low immunogenicity, batch-to-batch consistency, excellent solubility. Additionally, the type dressing significantly affects wound repair. Gels are ideal for sunburn treatment because they maintain a moist environment, adhere firmly, do not need be removed. Herein, we created bioactive triple-helical recombinant collagen (THRC) gels improved healing sunburned skin. The THRC remained stable after three-month stability test, displaying rheological behavior characteristic non-Newtonian pseudoplastic fluids. In vivo irritation tests conducted on New Zealand rabbits demonstrated that were safe use. A mice model was established study biological effects gels. Non-invasive combo evaluations indicated exhibited exceptional capability recovering dermis density, erythema index (EI), hydration, transepidermal water loss (TEWL) healthy state. Histological observations revealed enhanced repair damaged accelerating recovery process, promoting deposition regeneration. Molecular characterizations further remarkable antioxidant properties, including inhibition lipoperoxidation enhancement in superoxide dismutase (SOD) glutathione (GSH) activities. These provide novel approach show potential long-term cosmetic benefits.
Language: Английский
Citations
2
Advances in polymer science, Journal Year: 2024, Volume and Issue: unknown
Published: Jan. 1, 2024
Language: Английский
Citations
1
Journal of Molecular Structure, Journal Year: 2024, Volume and Issue: unknown, P. 140992 - 140992
Published: Dec. 1, 2024
Language: Английский
Citations
1
Colloids and Surfaces B Biointerfaces, Journal Year: 2024, Volume and Issue: 247, P. 114453 - 114453
Published: Dec. 10, 2024
Language: Английский
Citations
0