Macromolecular Bioscience,
Journal Year:
2024,
Volume and Issue:
unknown
Published: June 6, 2024
Controlling
the
growth
of
microbial
consortia
is
great
significance
in
biomedical
field.
Selective
bacterial
achieved
by
fabricating
silk
inverse
opal
(SIO)
scaffolds
with
varying
pore
sizes
ranging
from
0.3
to
4.5
µm.
Pore
size
significantly
influences
dynamics
bacteria
both
single
and
mixed-strain
cultures.
Specially,
SIO-4.5
µm
scaffold
observed
be
more
favorable
for
cultivating
S.
aureus,
whereas
SIO-0.3
suitable
E.
coli
P.
aeruginosa.
By
adjusting
secondary
conformation
fibroin,
stiffness
SIO
substrate
will
altered,
which
results
increase
on
16
times
compared
that
fibroin
film.
Manipulating
allows
adjustment
aureus
aeruginosa
ratio
0.8
9.3,
highlighting
potential
this
approach
regulating
culture.
Small,
Journal Year:
2025,
Volume and Issue:
unknown
Published: March 19, 2025
Abstract
Hydrogel
microspheres
are
important
in
regenerative
medicine
and
tissue
engineering,
acting
as
cargos
of
cells,
drugs,
growth
factors,
bio‐inks
for
3D
printing,
medical
devices.
The
antimicrobial
anti‐inflammatory
characteristics
hydrogel
good
treating
injured
tissues.
However,
the
biological
properties
should
be
modified
optimal
treatment
various
body
parts
with
different
physiological
biochemical
environments.
In
addition,
specific
preparation
methods
required
to
produce
customized
shapes
sizes
clinical
applications.
Herein,
advances
biomedical
applications
reviewed.
Synthesis
precursor
solutions,
manufacturing
methods,
strategies
enhancing
functions
these
described.
involvement
bioactive
repair
is
also
discussed.
This
review
anticipates
fostering
more
insights
into
design,
production,
application
biomedicine.
Natural
biomaterials
have
been
showing
extensive
potential
in
wound
healing;
attempts
therefore
focus
on
productions
achieving
both
antimicrobial
and
tissue
regenerative
abilities.
Here,
we
construct
a
decellularized
human
colon
tumor
(DHCT)-derived
scaffold
for
remolding
via
microfluidic
bioprinting.
The
DHCT
retains
series
of
growth
factors,
fibrin,
the
collagen
configuration,
that
favor
repair
reconstruction.
Specifically,
shows
superior
abilities
cell
migration
angiogenesis.
biocompatible
is
also
imparted
with
adhesion
ability
photothermal
effect
due
to
coating
biologically
derived
polydopamine
surface.
strong
under
near-infrared
irradiation
present
an
antibacterial
rate
exceeding
90%.
Furthermore,
vivo
experiments
convinced
polydopamine-integrated
can
markedly
expedite
healing
process
acute
wounds.
These
findings
indicate
composite
materials
from
natural
tumors
substantial
pertinent
clinical
applications.
Gels,
Journal Year:
2024,
Volume and Issue:
10(4), P. 219 - 219
Published: March 24, 2024
Bacterial
infections
impede
the
wound
healing
process
and
can
trigger
local
or
systemic
inflammatory
responses.
Therefore,
there
is
an
urgent
need
to
develop
a
dressing
with
antimicrobial
anti-inflammatory
properties
promote
of
infected
wounds.
In
this
study,
BA/COs/NO-PL/AL
hydrogels
were
obtained
by
adding
brevilin
A
(BA)
camellia
oil
(CO)
submicron
emulsion
nitric
oxide
(NO)
consisting
sodium
alginate
(AL)
Pluronic
F127
(PL).
The
characterized
through
dynamic
viscosity
analysis,
differential
scanning
calorimetry,
rheology.
They
evaluated
anti-inflammatory,
antimicrobial,
property
analyses.
results
showed
that
thermo-responsive
had
good
ex
vivo
in
activity,
they
also
exhibited
strong
activity
against
methicillin-resistant
Staphylococcus
aureus
Pseudomonas
aeruginosa
(MRPA)
(MRSA).
able
effectively
model
reduce
inflammation
bacterial
burden.
H&E
Masson’s
staining
promoted
normal
epithelial
formation
collagen
deposition.
conclusion,
are
promising
candidates
for
promoting
Small,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 30, 2024
Abstract
Bacterial
infected
wounds
bring
an
economic
burden
to
the
worldwide
medical
care
field.
A
variety
of
bioactives‐integrated
hydrogel
patches
are
developed
in
response
this
challenge.
Here,
melanin
inverse
opal
microneedle
(MNs)
with
antioxidant
and
visual
color
sensing
abilities
for
management
bacterial
proposed.
The
MNs
fabricated
by
applying
melanin‐loaded
polyethylene
glycol
diacrylate
(PEGDA)
as
using
bacitracin‐carried
gelatin
fill
those
nanopores
scaffold.
Benefitting
from
capacity
nanoparticles
local
antimicrobial
ability
bacitracin,
resulting
possess
integrated
functions
reactive
oxygen
species
scavenging
antibacterial.
Besides,
structure
endows
vivid
detectable
reflected
wavelength,
which
can
gradually
shift
release
drug,
thus
allowing
assess
drug
delivery.
Based
on
these
characteristics,
perform
excellent
vitro
delivery
monitoring,
well
promotion
wound
recovery
vivo,
indicating
potential
future
