Micro and nano-encapsulated natural products in yogurt: An emerging trend to achieve multifunctional benefits in product quality and human health.

Food Hydrocolloids, Journal Year: 2024, Volume and Issue: 154, P. 110124 - 110124

Published: April 21, 2024

Language: Английский

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Construction of Fu brick tea polysaccharide-cold plasma modified alginate microgels for probiotic delivery: Enhancing viability and colonization

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 268, P. 131899 - 131899

Published: April 25, 2024

Language: Английский

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Tethering pH-Induced Structural Modifications of Ovomucin to Stabilize W1/O/W2 Double Emulsions for Enhanced Protection of Companilactobacillus crustorum MN047

Food Hydrocolloids, Journal Year: 2025, Volume and Issue: 163, P. 111060 - 111060

Published: Jan. 7, 2025

Language: Английский

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Microenvironment-sensitive hydrogels as promising drug delivery systems for co-encapsulating microbial homeostasis probiotics and anti-inflammatory drugs to treat periodontitis

Materials Today Bio, Journal Year: 2025, Volume and Issue: 32, P. 101711 - 101711

Published: March 27, 2025

Developing and utilizing effective local antimicrobial agents can help treat periodontitis while minimizing the risks associated with systemic antibiotic use. Recent studies have shown that mucosal adhesion properties of hydrogels play a potential role in treatment periodontitis. The hydrogel improve contact retention time drugs periodontal pocket. Through mucosa, it interacts mucin coating surface epithelium teeth to form specific interface force. exhibits strong (adhesion strength: 5-6 N/cm2) prolonged pockets (≥6 h), enabling sustained drug release through dynamic sol-gel transitions triggered by pH reactive oxygen species (ROS). This design overcomes limitations poor mechanical stability conventional formulations. balance oral microbiota plays an important maintaining health. Probiotics, colonizing cavity, transform infected site from environment rich inflammatory cytokines more benign environment, inhibit harmful pathogenic microorganisms, contribute overall Microenvironment sensitive perform sol gel transformation situ, accurately control when exposed various stimuli (such as temperature change, light, species, etc.). Oral probiotics anti-inflammatory are encapsulated proliferation pathogens planting mouth producing metabolites, effectively preventing treating diseases.

Language: Английский

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Different polysaccharide-enhanced probiotic and polyphenol dual-functional factor co-encapsulated microcapsules demonstrate acute colitis alleviation efficacy and food fortification

Carbohydrate Polymers, Journal Year: 2024, Volume and Issue: 345, P. 122572 - 122572

Published: Aug. 3, 2024

Language: Английский

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Recent trends in nanocellulose: Metabolism-related, gastrointestinal effects, and applications in probiotic delivery

Carbohydrate Polymers, Journal Year: 2024, Volume and Issue: 343, P. 122442 - 122442

Published: July 1, 2024

Language: Английский

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A thiolated oxidized guar gum and sodium alginate dual-network microspheres with enhanced gastric acid resistance and mucoadhesion for delivery of probiotics

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 275, P. 133395 - 133395

Published: June 30, 2024

Language: Английский

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A comprehensive review of the characterization, host interactions, and stabilization advancements on probiotics: Addressing the challenges in functional food diversification

Comprehensive Reviews in Food Science and Food Safety, Journal Year: 2024, Volume and Issue: 23(5)

Published: Aug. 13, 2024

The demand for functional food is rising in tandem with the prevalence of chronic diseases. Probiotics play a crucial role development, yet their ability to confer health benefits host remains topic debate according Food and Agriculture Organization/World Health Organization requirements. application culturomics, innovative isolation techniques, within realm probiotics increasingly deemed essential fully harnessing latent potential microbial reservoirs. Nevertheless, its confined predominantly human fecal sources. Following integration probiogenomics, significant advancements have been made safety assessment probiotics. However, adoption novel probiotic microorganisms has match requisite pace. Progress research concerning host-probiotic interactions by employing omics technologies, particularly animal models, notable. Nonetheless, comprehensive elucidation mechanisms action trial studies are lagging behind. Additionally, viability probiotics, spanning from production as foods transit colon, markedly improved through encapsulation techniques. opportunities exploration persist regarding alternative coating materials diverse methodologies. Furthermore, there discernible transition domain probiotic-based foods, shifting away primarily dairy-centric focus toward inclusion broader array categories. This review addresses critical issues ranging sources techniques final developments. while doing so, it explores probiogenomics applications characterization, investigations into interactions, strategies stabilization under harsh environmental conditions.

Language: Английский

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Designing & optimisation of dual Ca ²⁺ and SO ₄ ^2– ionic cross-linked sericin/pectin microbeads using response surface methodology for colon-specific delivery

Journal of Biomaterials Science Polymer Edition, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 26

Published: Jan. 15, 2025

Ulcerative colitis, a chronic inflammatory condition of the colon, requires precise and targeted treatment, polysaccharides, with their pH responsiveness biodegradability, offer an innovative approach for colon-specific drug delivery. This study aims to develop highly delivery system enhanced therapeutic targeting efficiency ulcerative focusing on preparation, optimisation, evaluation dual cross-linked mesalamine-loaded sericin-pectin (DCLSPs) micro-beads. These beads utilise pH-responsive microflora biodegradability properties polysaccharides colon delivery, employing Response Surface Methodology. Formulated via ionotropic gelation method divalent cross-linking ions (Ca2+ SO42–), DCLSPs were optimised using Box-Behnken design assess impact varying drug, pectin, sericin polymer proportions. The evaluated entrapment efficiency, thermal behaviour, surface morphology, water uptake, swelling, in-vitro release. Results indicated that spherical successfully developed, encapsulation ranging from 65.1% 95.5%, loading between 32.5% 49.9%, bead sizes 0.75 mm 0.92 mm, degrees swelling 1.82. Drug release was controlled by both diffusion mechanisms, as supported Higuchi Korsmeyer-Peppas models. formulation demonstrated high strong adhesion ensuring extended retention at site. Additionally, incorporation accuracy Gaussian fitting particle size distribution. Overall, show potential mucoadhesive carriers delivering drugs specifically colon.

Language: Английский

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Microfluidic design and preparation of hydrogel microcapsules of Mesona chinensis polysaccharide: Characterization, pH-responsive behavior and gastrointestinal protection for Lactobacillus plantarum

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 140446 - 140446

Published: Jan. 1, 2025

Language: Английский

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