A Cell Adhesive Radial Nanofiber Membrane for Promoting Diabetes Wound Healing DOI
Ning Wang, Tianyu Wang, Rongda Zhang

et al.

ACS Applied Polymer Materials, Journal Year: 2024, Volume and Issue: 7(1), P. 258 - 267

Published: Dec. 27, 2024

Diabetic wounds are extremely difficult to heal due the long duration and high recurrence rate. The bacterial infection caused by elevated blood glucose negatively affects speed of wound healing. In this article, radially oriented nanofibers containing natural antimicrobial agent purslane were prepared electrostatic spinning. Subsequently, asiaticoside was loaded onto surface fibers spraying. experimental results indicated that radial nanofiber membranes exhibited uniform diameter distribution, suitable water vapor permeability, good hydrophilicity as well excellent antibacterial performance biocompatibility. Due ordered arrangement, healing ability, regular granulation tissue growth, collagen deposition. More importantly, fiber structure significantly promoted cell proliferation adhesion. Based on these results, with a have potential application prospects in field chronic diabetic

Language: Английский

Activation of IL-2/IL-2R pathway by Hedyotis diffusa polysaccharide improves immunotherapy in colorectal cancer DOI
Liangliang Bai, Xiaoxia Liu,

Ze Yuan

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 141013 - 141013

Published: Feb. 1, 2025

Language: Английский

Citations

0
Genus Paeonia polysaccharides: A review on their extractions, purifications, structural characteristics, biological activities, structure-activity relationships and applications DOI
Wenjing Hu,

Aiqi Yu,

Zhibin Wang

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 137089 - 137089

Published: Oct. 1, 2024

Language: Английский

Citations

2
Extraction and Structural Characterization of Four Grape Polysaccharides and Their Protective Effects in Alcohol-Induced Gastric Mucosal Injury DOI Creative Commons
Jian Shao, Jizhen Li,

Yonghui Zhao

et al.

Foods, Journal Year: 2024, Volume and Issue: 13(21), P. 3500 - 3500

Published: Oct. 31, 2024

Grapes, recognized as a nutritionally rich fruit, have been found through extensive research to contain various bioactive components. However, the roles of polysaccharides and their properties remain unclear. Based on this, in our research, four different grape were obtained using an enzymatic-assisted extraction method. We investigated compared physicochemical properties, antioxidant activities, protective effects gastric mucosa mice. The results indicated that monosaccharide compositions these specific similar; however, molar ratios, molecular weights, morphological characteristics varied. radical scavenging tests revealed red-fleshed polysaccharide (RFP) exhibited superior properties. In vivo assessments demonstrated RFP protects against mucosal injury mice by inhibiting inflammation generation. Therefore, from holds potential application value pharmaceutical food industries.

Language: Английский

Citations

1
A Cell Adhesive Radial Nanofiber Membrane for Promoting Diabetes Wound Healing DOI
Ning Wang, Tianyu Wang, Rongda Zhang

et al.

ACS Applied Polymer Materials, Journal Year: 2024, Volume and Issue: 7(1), P. 258 - 267

Published: Dec. 27, 2024

Diabetic wounds are extremely difficult to heal due the long duration and high recurrence rate. The bacterial infection caused by elevated blood glucose negatively affects speed of wound healing. In this article, radially oriented nanofibers containing natural antimicrobial agent purslane were prepared electrostatic spinning. Subsequently, asiaticoside was loaded onto surface fibers spraying. experimental results indicated that radial nanofiber membranes exhibited uniform diameter distribution, suitable water vapor permeability, good hydrophilicity as well excellent antibacterial performance biocompatibility. Due ordered arrangement, healing ability, regular granulation tissue growth, collagen deposition. More importantly, fiber structure significantly promoted cell proliferation adhesion. Based on these results, with a have potential application prospects in field chronic diabetic

Language: Английский

Citations

0