PROPOLIS JAKO FUNKCJONALNY SKŁADNIK ŻYWNOŚCI DOI Open Access
Lesław Juszczak, Agnieszka Cabaj

Żywność, Journal Year: 2023, Volume and Issue: 30(2), P. 144 - 162

Published: Jan. 1, 2023

Background. Propolis is a resinous substance collected by honey bees (Apis mellifera) from various plant sources. It commonly called bee glue and used to protect the hive. Because propolis contains numerous secondary metabolites, its type closely related species of which it comes. Several hundred chemical substances have been identified in propolis, including: balsamic substances, waxes, essential oils, pollen tannins. most often treat disinfect skin, diseases ears, mouth, throat, maxillary sinuses, as an antifungal, anti inflammatory analgesic. stimulates immune system, relieves inflammation weakness upper respiratory tract. has antibacterial antiviral properties. prevents hemorrhoids, facilitates regeneration mucous membrane, accelerates healing wounds ulcers, also anti-inflammatory, anesthetic regenerating Due compo sition properties, can be valuable raw material for food industry. The aim this work was review literature on possibility using ingredient assess role foodstuffs. Results conclusions. strong antioxidant antimicrobial effects, making at tractive natural product that incorporated into foods functional ingredient. Enriching products with improve nutritional value, quality functionality subject studies due origin multidirectional impact. results published research shown foods, such meat, dairy, juices, fruits, oils seafood, extend shelf life, prevent lipid oxidation provide health benefits consumers. However, compounds strong, characteristic taste aroma, causes changes sensory properties food.

Language: Английский

Multi-pronged molecular insights into flavonoid-mediated inhibition of squalene epoxidase: a pathway to novel therapeutics DOI Creative Commons
Emadeldin M. Kamel,

Sarah I. Othman,

Hassan A. Rudayni

et al.

RSC Advances, Journal Year: 2025, Volume and Issue: 15(5), P. 3829 - 3848

Published: Jan. 1, 2025

Apigenin-7-O-glucoside, silibinin, and baicalin are potent squalene epoxidase inhibitors with promising therapeutic potential. Integrative in silico experimental studies pave the way for hypercholesterolemia antifungal therapies.

Language: Английский

Citations

10
A review on dynamic pharmacological potency and multifaceted biological activities of propolis DOI Creative Commons
Neelam Bhatti,

Younis Ahmad Hajam,

Saresh Mushtaq

et al.

Discover Sustainability, Journal Year: 2024, Volume and Issue: 5(1)

Published: Aug. 8, 2024

Abstract This review explores the therapeutic potential of propolis, a natural resin produced by bees, analyzing recent literature spanning from 2005 to 2023. Various databases including Google Scholar, Web Science, Science Direct, PubMed, SCOPUS, and WoS were searched uncover findings. Propolis exhibits diverse array pharmacological properties, antimicrobial, anti-inflammatory, antioxidant, immunomodulatory, wound-healing effects. It shows promise in treating respiratory infections, oral diseases, gastrointestinal disorders, skin conditions. Additionally, research suggests its as an anticancer agent. The also investigates efficacy propolis addressing antiviral, antibacterial, metabolic disorders (diabetes), reproductive disorder (PCOS), cardiovascular hepatotoxicity, wound healing properties propolis. Hence, could emerge remedy with significant for enhancing healthcare outcomes.

Language: Английский

Citations

8
A multifunctional gingival retraction cord with antibacterial and hemostasis properties based on Chitosan/Propolis/Tranexamic acid for dental treatment DOI
Wenjing Zhang,

Hongxing Xu,

Fan Feng

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 277, P. 134237 - 134237

Published: July 30, 2024

Language: Английский

Citations

4
The application of medicine and food homology in the management of chronic heart failure DOI Creative Commons
Haipeng Yin, Herong Cui, Zixuan Zhang

et al.

Journal of Traditional Chinese Medical Sciences, Journal Year: 2025, Volume and Issue: unknown

Published: March 1, 2025

Language: Английский

Citations

0
Distribution of phthalic acid esters in propolis ethanolic extract and capsuled propolis DOI
Rifat Nowshin Raka, Haitao Xu,

Meichao Bu

et al.

Food Additives & Contaminants Part A, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 11

Published: April 4, 2025

Phthalate esters (PAEs), commonly used in food packaging materials, pose a potential health risk due to their migration into matrices. Propolis, resinous bee product widely consumed for its benefits, is often packaged plastics, raising concerns about PAE contamination. However, the occurrence of PAEs within propolis has been scarcely investigated. This study quantified contamination profiles ethanolic extracts (PE) and capsules (PCs) from China. The GC-MS/MS analysis 20 demonstrated high linearity, indicating reliability method. limits quantification (LOQ) ranged 1.3 26.2 µg/kg, detection (LOD) 0.4 8.6 µg/kg. Matrix effects between 9% 33%. Five were detected PE samples: dimethyl phthalate (DMP), diethyl (DEP), diisobutyl (DiBP), dibutyl (DBP) bis(2-ethylhexyl)phthalate (DEHP). Seventeen PC samples, with 15 consistently present all samples (100% positivity). Diallyl (DAP), dipropyl (DPrP) di-n-octyl (DNOP) not any sample. total mean concentration 17 (∑17 PAEs) 0.87 mg/kg 23.71 mg/kg. found that had highest DBP (0.24 mg/kg) di-heptyl (DHP: 2.29 levels on average, respectively. While showed higher than PE. Therefore, this provides insight raw extract encapsulated propolis.

Language: Английский

Citations

0
Effects of unsaturated fatty acid-rich diets supplemented with antioxidants on lipid and fatty acid metabolism in high-fat rats DOI

Manyu Helian,

Niu Xian,

Xiaoqi Zhou

et al.

Food Science of Animal Products, Journal Year: 2025, Volume and Issue: 3(2), P. 9240119 - 9240119

Published: April 8, 2025

Language: Английский

Citations

0
The Chemical and Biological Properties of Propolis DOI

Weam Siheri,

Samya Alenezi, Jonans Tusiimire

et al.

Published: Jan. 1, 2025

Language: Английский

Citations

0
Phytochemical Regulation of CaMKII in Alzheimer’s Disease: A Review of Molecular Mechanisms and Therapeutic Potential DOI Creative Commons

Zhongying Lin,

Miao Sun

Pharmacological Research, Journal Year: 2025, Volume and Issue: 216, P. 107790 - 107790

Published: May 21, 2025

Language: Английский

Citations

0
Antioxidant, Antibacterial, and Bioaccessibility Properties of Ultrasound-Extracted Chilean Propolis DOI Creative Commons

Jessica Mejía,

Claudia Giovagnoli-Vicuña, Cristián Jacob

et al.

Antioxidants, Journal Year: 2025, Volume and Issue: 14(6), P. 651 - 651

Published: May 28, 2025

Propolis is a honeybee product with significant biological properties, strongly influenced by geographic and floral origin as well extraction method. Ultrasound-assisted (UAE) an emerging alternative for propolis preparation. This study aimed to determine the optimal UAE conditions total polyphenol content (TPC) flavonoid (TFC) in Chilean compare its antioxidant antimicrobial capacities conventional was performed varying ethanol concentrations (50–90%), temperatures (20–60 °C), times (10–50 min), keeping solid/liquid ratio constant at 1:10 (w/v). The ethanolic extract (OE) compared (CE) activity against Salmonella enterica Listeria monocytogenes capacity (DPPH, ABTS, FRAP assays). Optimal were 80% ethanol, 30 °C, min. OE showed significantly higher (p < 0.05) TPC (22.4 ± 0.3 mg GAE/mL), TFC (15.7 0.7 QE/mL), (ABTS: 35.7 0.9; DPPH: 62.9 0.3; FRAP: 49.7 2.1 µmol TE/mL), evaluated Gram-positive bacteria (>15 mm inhibition halo, MBC = 3.1 mg/mL) CE. bioaccessibility analysis revealed that maintained 20.1% of 69.5%, 60.5%, 61.9% DPPH, FRAP, respectively, after simulated gastrointestinal digestion. established generated extracts increased content, capacity, activity, bioaccessibility, indicating potential method enhanced bioactivity.

Language: Английский

Citations

0
Does Green Brazilian Propolis Extract Improve Functional Capacity in Symptomatic Chronic Coronary Disease?—A Pilot Randomized Trial DOI Creative Commons
Clara Salles Figueiredo, Luíz Carlos Santana Passos, Caio Rebouças Fonseca Cafezeiro

et al.

Pharmaceuticals, Journal Year: 2025, Volume and Issue: 18(6), P. 827 - 827

Published: May 31, 2025

Background: Inflammation plays a critical role in the progression of coronary heart disease (CHD). Low-dose colchicine has shown promise reducing cardiovascular events, and green Brazilian propolis extract (EPP-AF® (standardized extract) was provided by Apis Flora Indl. Coml. Ltda, Ribeirão Preto, SP, Brazil), known for its anti-inflammatory properties, may offer additional therapeutic benefits. This pilot study aimed to evaluate whether six weeks EPP-AF® supplementation improves functional capacity assessed treadmill exercise testing. Methods: randomized, double-blind, placebo-controlled conducted at clinic Brazil. Patients aged ≥ 18 years with stable CHD receiving optimized medical therapy were randomized 2:1 ratio receive either 200 mg or placebo twice daily weeks. The primary outcome change duration (in seconds). Secondary outcomes included total time, (measured metabolic equivalents task [METs]), high-sensitivity C-reactive protein (hs-CRP) levels, Seattle Angina Questionnaire (SAQ), Canadian Cardiovascular Society (CCS) angina classification. Statistical analysis performed on an intention-to-treat basis. Results: A 59 patients median follow-up 6.5 There no significant difference endpoint between groups: test time 39 s group versus 30 (p = 0.83). No improvements observed METs, hs-CRP SAQ scores, CCS class group. major adverse events occurred during study. Conclusions: did not improve capacity, inflammatory markers, symptoms compared placebo.

Language: Английский

Citations

0