Preparation of sodium alginate antibacterial porous composite pads embedded with centrifugally spun nanofibers by freeze-drying and recasting for active food packaging

Carbohydrate Polymers, Journal Year: 2025, Volume and Issue: 355, P. 123430 - 123430

Published: Feb. 21, 2025

Language: Английский

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Antioxidant activity, antibacterial behavior, and anticancer impact of Egyptian propolis.

PubMed, Journal Year: 2025, Volume and Issue: 15(1), P. 126 - 138

Published: Jan. 1, 2025

Propolis, a resinous substance produced by bees, exhibits significant phytochemical and biological properties, which have been explored for various therapeutic applications. This study investigates the composition, antioxidant activity, antibacterial efficacy, anticancer potential of ethanolic extracts from three propolis samples (P1, P2, P3). Phytochemical screening was conducted to determine presence bioactive compounds, such as ascorbic acid, saponins, tannins. Antioxidant activity evaluated using phosphomolybdate (PMA) ferric reducing power (FRP) assays. The efficacy against Salmonella Typhimurium Staphylococcus aureus assessed well diffusion method. Cytotoxicity effects were investigated MTT assay on red blood cells (RBCs) carcinoma cell lines (HepG2, MDA, A549). Gene expression analysis performed RT-qPCR assess upregulation immune response genes (P53, Bcl2, Bax, Ca125, C3). revealed considerable quantities tannins in samples. P1 sample exhibited most substantial with FRP values at 62.9 mg/g DM PMA content 20.7 DM. In assays, demonstrated highest inhibitory zones maximum concentration (400 mg/ml), outperforming standard antibiotic treatments. cytotoxicity preserved percentage RBCs hemolysis showed marked lowest viability observed 3.9 µg/ml. genes, particularly MDA HepG2 upon treatment. underscores potent antioxidant, antibacterial, properties propolis, highlighting its natural agent. activities suggest promising applications combating bacterial infections cancer types, warranting further exploration into molecular mechanisms clinical uses.

Language: Английский

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Ecological packaging and creating sustainable solutions for biodegradable cellulose derivatives: A review

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 142348 - 142348

Published: March 1, 2025

Language: Английский

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Harnessing nanofibers for targeted delivery of phytoconstituents in age-related macular degeneration

Drug Delivery, Journal Year: 2025, Volume and Issue: 32(1)

Published: April 7, 2025

Age-related macular degeneration is a degenerative eye condition that affects the macula and results in central vision loss. Phytoconstituents show great promise treatment of AMD. AMD therapy can benefit from advantages phytoconstituents loaded nanofibers. There are opportunities to improve effectiveness age-related (AMD) through use nanofiber-based delivery methods. These novel platforms encapsulate distribute plant-derived bioactives by making special qualities include their high surface area-to-volume ratio, variable porosity, biocompatibility. Exploring methods provide choice for enhancing patient adherence, safety, efficacy managing this condition. This article explores potential revolutionize treatment, providing an innovative effective approach treat

Language: Английский

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Chemical modifications of cellulose nanoparticles for anticancer applications: perspective since 2020

Cellulose, Journal Year: 2024, Volume and Issue: 31(14), P. 8403 - 8444

Published: Aug. 28, 2024

Language: Английский

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Recent progress in cellulose derivatives and cellulose-based composites for bioimaging and anticancer applications (2020–2024)

Cellulose, Journal Year: 2024, Volume and Issue: 31(17), P. 10063 - 10086

Published: Oct. 21, 2024

Language: Английский

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