A multifunctional polyvalent DNA scaffolds-based photothermal aptasensor for visible and portable detection of aflatoxin B1
Shanglin Li,
No information about this author
Ziyang He,
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Yonghong Meng
No information about this author
et al.
LWT,
Journal Year:
2025,
Volume and Issue:
unknown, P. 117714 - 117714
Published: March 1, 2025
Language: Английский
Advancements in DNAzyme-based biosensors for the detection of hazardous substances in foodstuff: current applications and future perspectives
Taolin Li,
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Yijia Zhang,
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Weiwei Cheng
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et al.
Critical Reviews in Food Science and Nutrition,
Journal Year:
2025,
Volume and Issue:
unknown, P. 1 - 20
Published: April 6, 2025
DNAzyme-based
biosensors
have
emerged
as
a
promising
tool
for
ensuring
food
safety
due
to
their
high
sensitivity,
specificity,
and
potential
rapid,
cost-effective
detection
of
hazardous
substances.
These
leverage
DNAzymes-catalytically
active
DNA
molecules-to
detect
range
contaminants,
including
metal
ions,
fungal
toxins,
pesticides,
pathogens.
While
show
significant
advantages
over
conventional
techniques,
challenges
such
nuclease
degradation,
interference
from
complex
sample
matrices,
the
costs
associated
with
DNAzyme
synthesis
still
hinder
widespread
application.
Recent
advancements
in
stability
DNAzymes,
immobilization
strategies,
integration
nanomaterials
are
progressively
addressing
these
limitations,
enhancing
performance
reliability
sensors.
This
review
highlights
structural
catalytic
characteristics
assesses
current
applications
safety,
discusses
innovative
strategies
overcome
existing
challenges.
The
continuous
evolution
biosensors,
particularly
design
device
integration,
holds
great
promise
future
role
routine,
reliable
analysis.
Language: Английский
A colorimetric and electrochemical dual-modal ochratoxin a aptasensor based on branched hybridization chain reaction signal amplification
Bioelectrochemistry,
Journal Year:
2025,
Volume and Issue:
unknown, P. 108984 - 108984
Published: April 1, 2025
Language: Английский
A dual-mode aptasensor based on rolling circle amplification enriched G-quadruplex for highly sensitive IFN-γ detection
Lianhui Zhao,
No information about this author
Yingai Yin,
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Shuqi Xiao
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et al.
Analytica Chimica Acta,
Journal Year:
2024,
Volume and Issue:
1329, P. 343254 - 343254
Published: Sept. 17, 2024
Language: Английский
CRISPR/Cas12a-Based Indirect Competitive Enzyme-Linked Immunosorbent Assay for Sensitive Detection of Ochratoxin A
Xinqi Long,
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Tian Zhang,
No information about this author
Yang Lü
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et al.
Journal of Agricultural and Food Chemistry,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Sept. 20, 2024
The
high
toxicity
and
widespread
contamination
of
ochratoxin
A
(OTA)
make
it
urgent
to
develop
a
sensitive
method
detect
trace
OTA
in
complex
food
matrices.
Herein,
an
indirect
competitive
enzyme-linked
immunosorbent
assay
(icELISA)-based
on
the
CRISPR/Cas12a
system
is
described.
DNA
amplicons
with
multiple
activation
sequences
were
pre-prepared
improve
detection
sensitivity.
In
absence
OTA,
streptavidin-mediated
biotinylated
captured
by
secondary
antibody
microplate.
activated
system,
which
thereby
effectively
cleaved
reporter
DNA,
producing
strong
fluorescence.
presence
led
decrease
microplate,
resulting
Cas12a
ultimately
drop
fluorescence
intensity.
matrices
at
nanogram
per
milliliter
levels
can
be
detected.
Therefore,
new
has
great
potential
monitoring
OTA.
Language: Английский
Multi-DNAzymes cascade reaction mediated aptasensors for OTA detection based on the integration of autocatalytic Mg2+-dependent DNAzyme cleavage and entropy-driven circuit
Wenshan Li,
No information about this author
Qingqing Li,
No information about this author
Huaiyue Xia
No information about this author
et al.
International Journal of Biological Macromolecules,
Journal Year:
2024,
Volume and Issue:
289, P. 138896 - 138896
Published: Dec. 18, 2024
Language: Английский