Journal of Thrombosis and Haemostasis, Journal Year: 2024, Volume and Issue: unknown
Published: Oct. 1, 2024
Language: Английский
Journal of Thrombosis and Haemostasis, Journal Year: 2024, Volume and Issue: unknown
Published: Oct. 1, 2024
Language: Английский
International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 139653 - 139653
Published: Jan. 1, 2025
Language: Английский
Citations
1International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 142326 - 142326
Published: March 1, 2025
Language: Английский
Citations
0Polysaccharides, Journal Year: 2025, Volume and Issue: 6(2), P. 25 - 25
Published: March 28, 2025
Bleeding is a potentially life-threatening emergency that can result in severe complications or death regardless of the cause bleeding. The development hemostatic materials has been long-standing concern for treatment surgery and combat. In recent years, there have many reviews on materials, but few specific studies about performance requirements years natural polysaccharide-based sponge as type excipient. Currently, polysaccharide attracted wide attention due to enhancement interaction various mechanisms. These sponges show high effect. this paper, application history polysaccharides (chitosan, hyaluronic acid, alginate, cellulose, starch, etc.) new generation reviewed. design principles achievements are introduced. Finally, we summarize advantages disadvantages prospect opportunities challenges material.
Language: Английский
Citations
0Pharmaceutics, Journal Year: 2025, Volume and Issue: 17(5), P. 578 - 578
Published: April 28, 2025
Background/Objectives: Efficient wound treatment embraces the management of four overlapping phases, starting with hemostasis, an immediate physiological response aimed at stopping bleeding from damaged blood vessels caused by skin injury. This paper proposes innovative, nature-based hemostatic biomaterial designed to assist natural self-healing regenerative mechanisms. Methods: Light, transparent, and skin-adhesive films based on κ-carrageenan, meadow polyfloral honey, Calendula officinalis flower extract were fabricated via solution casting. Comprehensive characterization revealed physicochemical, structural, swelling, barrier properties influence each bioactive compound utilized for film preparation. Results: The samples subcutaneously implanted in Wistar rats induced vascularization, deposition collagen, orientation collagen fibers while being fully phagocytosed gradually biodegraded. rat tail-cut model demonstrated that significantly reduced loss (0.1875 ± 0.0732 g) compared control (0.7837 0.3319 g), hemostasis was achieved notably faster (355.75 71.42 s) than group (704.25 85.29 s). liver punch biopsy confirmed (2.8025 1.5174 shorter time (303.25 77.90 (3.1475 1.5413 g, 383.00 36.53 Conclusions: results indicate great potential as dressings.
Language: Английский
Citations
0Journal of Thrombosis and Haemostasis, Journal Year: 2024, Volume and Issue: unknown
Published: Oct. 1, 2024
Language: Английский
Citations
2