Journal of Food Measurement & Characterization, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 30, 2024
Language: Английский
Journal of Food Measurement & Characterization, Journal Year: 2024, Volume and Issue: unknown
Published: Dec. 30, 2024
Language: Английский
Food and Bioprocess Technology, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 12, 2025
Language: Английский
Citations
3Future Foods, Journal Year: 2024, Volume and Issue: unknown, P. 100458 - 100458
Published: Sept. 1, 2024
Language: Английский
Citations
9Food Bioscience, Journal Year: 2024, Volume and Issue: unknown, P. 105183 - 105183
Published: Sept. 1, 2024
Language: Английский
Citations
4Journal of Agricultural and Food Chemistry, Journal Year: 2025, Volume and Issue: unknown
Published: April 8, 2025
Lactoferrin (LF), a multifunctional glycoprotein with high iron-binding affinity, plays critical role in modulating physiological processes through its ability to reversibly bind and release iron ions, existing two distinct states: iron-saturated (holo-LF, > 85% saturation) iron-deficient (apo-LF, < 5% saturation). However, the importance of saturation has been largely overlooked LF production research due lack standardized protocols. The level dictates functional specificity: apo-LF exhibits potent antimicrobial properties by chelating disrupting membrane integrity, while also significantly inhibiting oxidative stress, thereby alleviating neurological disorders immune responses. In contrast, holo-LF participates metabolism transport, influencing tumor cell proliferation systemic uptake. This review systematically evaluates interplay between levels LF's biological functions, emphasizing dual roles human homeostasis disease modulation. Future should prioritize elucidating mechanisms underlying saturation-dependent bioactivity metabolic differences, incorporating emerging technologies enhance stability refine measurement accuracy.
Language: Английский
Citations
0International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 142964 - 142964
Published: April 1, 2025
Language: Английский
Citations
0Food Bioscience, Journal Year: 2025, Volume and Issue: unknown, P. 106621 - 106621
Published: April 1, 2025
Language: Английский
Citations
0Trends in Food Science & Technology, Journal Year: 2024, Volume and Issue: unknown, P. 104761 - 104761
Published: Oct. 1, 2024
Language: Английский
Citations
3International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(4), P. 1404 - 1404
Published: Feb. 7, 2025
Lactoferrin (LF) is an 80 kDa glycoprotein that contains approximately 700 amino acids and a member of the transferrin family. The essential properties LF, including antimicrobial, antiviral, anticancer, anti-inflammatory, antioxidant, probiotic effects, have been studied for decades. iron chelation activity LF significantly associated with its antioxidant properties. Owing to prebiotic activity, also facilitates growth beneficial microorganisms iron-defense immediate-effect on pathogens. Additionally, ability regulate cell signaling pathways immune responses makes prominent modulatory protein. These diverse characteristics gained interest in therapeutic potential. Studies suggested could serve as alternative source antibiotics severe infections illnesses. has food industry potential additive fortify products such yogurt, infant formula, meat derivatives while improving shelf life foods providing antimicrobial activity. Prior using industry, safety toxicity processing are necessary be investigated. investigations crucial addressing harm or side effects ensuring healthy lifestyle. This review discusses attributes particularly exploitation industry.
Language: Английский
Citations
0Food Chemistry, Journal Year: 2025, Volume and Issue: 479, P. 143838 - 143838
Published: March 10, 2025
In this study, we investigated the mechanism of action 10-aminoacid RiLK1 peptide against Escherichia coli (strain ATCC 25922), both in vitro and contaminated meat matrices. Therefore, a mass spectrometry-based functional proteomics platform was employed to identify specific molecular targets membrane protein-enriched E. lysate obtain information on their interaction mechanism. This target deconvolution approach combines MS-limited proteolysis techniques, like Drug Affinity Responsive Target Stability (DARTS) targeted-limited Proteolysis coupled with Mass Spectrometry (t-LiP-MS). The b δ subunits multimeric enzymatic complex ATP synthase, smallest known biological nanomotor found all cells, were identified as relevant protein targets. Extensive docking biochemical analyses validated improved suggested profile. These unique findings could rationally explain bactericidal effects strains, suggesting its potential application food safety preservation.
Language: Английский
Citations
0Food Control, Journal Year: 2024, Volume and Issue: unknown, P. 110981 - 110981
Published: Oct. 1, 2024
Language: Английский
Citations
2