RECENT ADVANCES IN TREATMENT APPROACHES FOR DIABETES MELLITUS AND RELATED COMPLICATIONS: A REVIEW

International Journal of Applied Pharmaceutics, Journal Year: 2025, Volume and Issue: unknown, P. 12 - 30

Published: March 7, 2025

Diabetes Mellitus (DM) can be treated with a variety of therapeutic approaches. Patients are forced to initiate therapy antidiabetic agents when diet and exercise ineffective regulate hyperglycemia. However, these drugs have several disadvantages that influence the course treatment. The primary drawbacks current oral modalities for treatment DM immediate release drug low bioavailability, which necessitates an increase in frequency dosing. Patient compliance decreases conjunction manifestation adverse side effects. development innovative delivery potential improve efficacy anti-diabetic regimens has been fertile area nanotechnology recent years. objective all attempts (a) safeguard by encapsulating it nano-carrier system (b) controlled progressive manner using effective techniques. review aims compile nanocarriers like polymeric nanoparticles (NPs), liposomes, niosomes, dendrimers, micelles, solid lipid NPs, transfersomes, ethosomes, nanofibers, carbon nanotubes diabetes mellitus, emerging strategies various complications related this disease.

Language: Английский

Nanocochleates as novel delivery vehicles for enhancement of water solubility, stability and controlled release of dihydromyricetin in gastrointestinal tract

Food Research International, Journal Year: 2024, Volume and Issue: 197, P. 115174 - 115174

Published: Sept. 30, 2024

Language: Английский