Ceramics International, Journal Year: 2024, Volume and Issue: unknown
Published: Nov. 1, 2024
Language: Английский
Nanomaterials, Journal Year: 2025, Volume and Issue: 15(3), P. 196 - 196
Published: Jan. 26, 2025
Current investigations into the fabrication of innovative biomaterials that stimulate cartilage development result from increasing interest due to emerging bone defects. In particular, investigation for musculoskeletal therapies extensively depends on various hydroxyapatite (HA)/sodium alginate (SA) composites. Cuttlefish (CFB)-derived composite scaffolds hard tissue regeneration have been effectively illustrated in this using a hydrothermal technique. this, HA was prepared CFB source without altering its biological properties. The as-developed nanocomposites were investigated through XRD, FTIR, SEM, and EDX analyses confirm their structural, functional, morphological orientation. higher interfacial density HA/SA nanocomposites, more hardness scaffold increased with applied load. Furthermore, nanocomposite revealed remarkable antibacterial activity against bacterial strains such as E. coli S. aureus inhibition zones measured 18 mm 20 mm, respectively. results demonstrated minor decrease cell viability compared untreated culture, an observed percentage at 97.2% nanocomposites. Hence, proposed would be excellent alternative engineering applications.
Language: Английский
Citations
0
Current Issues in Molecular Biology, Journal Year: 2025, Volume and Issue: 47(3), P. 175 - 175
Published: March 7, 2025
Marine-derived biomaterials are emerging as promising candidates for tissue regeneration due to their sustainability, biocompatibility, bioactivity, and unique chemical structure. This review provides an overview of different marine-derived inorganic organic materials, such calcium carbonate, magnesium salts, silica, polysaccharides, bioactive peptides, lipid-based compounds, effects in promoting osteogenesis. Specifically, the osteoinductive, osteoconductive, osteointegrative activities traditional innovative materials that influence key molecular pathways BMP/Smad Wnt/β-catenin signaling underlying bone formation will be evaluated. also prospects approaches, i.e., phage display technology, optimize peptides targeted regeneration. In context sustainable this suggests some interesting applications unusual able overcome limitations conventional ones stimulate cellular by activating specific pathways.
Language: Английский
Citations
0
Journal of Functional Biomaterials, Journal Year: 2025, Volume and Issue: 16(4), P. 127 - 127
Published: April 2, 2025
The treatment of bone defects is complicated by clinical conditions, such as trauma, tumor resection, and infection, which result in impair the bone’s regenerative capacity. Hydroxyapatite (HAp), primary inorganic component bone, possesses good biocompatibility osteoconductivity. However, it has poor mechanical properties, a slow degradation rate, limited functionality, necessitating combination with other materials to broaden its application scope. This paper summarizes importance properties HAp composites provides categorized review current research on tissue engineering. These composite scaffolds not only offer excellent support for cell growth regeneration but also facilitate new formation vascularization. Additionally, challenges faced composites, material property optimization improvement preparation techniques, are discussed. applications defect repair, dental implants, spinal fusion, fields.
Language: Английский
Citations
0
The Science of The Total Environment, Journal Year: 2025, Volume and Issue: 978, P. 179426 - 179426
Published: April 21, 2025
Language: Английский
Citations
0
Journal of Biomedical Materials Research Part A, Journal Year: 2024, Volume and Issue: unknown
Published: Nov. 7, 2024
In recent years, the exploration of sustainable alternatives in field bone tissue engineering has led researchers to focus on marine waste byproducts as a valuable resource. These resources, often overlooked remnants various industries, exhibit rich composition hydroxyapatite, collagen, calcium carbonate, and other minerals essential complex framework structure. Marine by-products can emit gases such methane carbon dioxide, highlighting urgency repurpose these materials for innovative regeneration solutions, offering approach address environmental challenges while advancing medical science. Using discarded offers promising pathway development regenerative medicine. This review investigates distinctive properties byproducts, emphasizing their capacity be recycled effectively contribute rebuilding cartilage during processes. We also highlight compatibility resources with biological platelet-rich plasma (PRP), stem cells, exosomes, natural bioproducts, well nanoparticles (NPs) polymers. By using potential we simultaneously promote solutions skeletal engineering, initiating new era environmentally green biomedical research.
Language: Английский
Citations
2
Ceramics International, Journal Year: 2024, Volume and Issue: unknown
Published: Nov. 1, 2024
Language: Английский
Citations
0