Xuesanqi ameliorates DSS-induced colitis in mice by mediating gut microbiota dysbiosis and modulating MAPK/ERK/JNK pathway DOI

Qiyuan Su,

Qian Hu,

Songtao Wu

et al.

Natural Products and Bioprospecting, Journal Year: 2024, Volume and Issue: 14(1)

Published: Nov. 30, 2024

Language: Английский

Emerging Resistance and Virulence Patterns in Salmonella enterica: Insights into Silver Nanoparticles as an Antimicrobial Strategy DOI Creative Commons
Irina Gheorghe-Barbu, Ilda Czobor Barbu,

Rareș-Ionuț Dragomir

et al.

Antibiotics, Journal Year: 2025, Volume and Issue: 14(1), P. 46 - 46

Published: Jan. 7, 2025

Background/Objectives: This study aims to characterize antibiotic resistance (AR) and virulence markers in Salmonella spp. isolated from Romanian outpatients’ stool samples. Methods: In 2019, community-acquired strains were collected identified using MALDI-TOF mass spectrometry, susceptibility profiles have been determined with the MicroScan system, soluble factors evaluated specific culture media, while biofilm formation was quantified 96-well plates. Molecular analysis targeted genes for β-lactams (e.g., blaTEM blaSHV); tetracyclines tet(A)); sulphonamides; quinolones, as well invA, spvC, pldA, held). Whole-genome sequencing (WGS) performed on 19 selected isolates. A silver nanoparticles (AgNPsol) alternative conventional antibiotics tested effectiveness against multidrug-resistant (MDR) Results: From total of 309 isolates (65.05% children under 4 years age) belonging four subtypes serovars, 27.86% showed at least one antibiotic, most frequently tetracycline, ampicillin, piperacillin. The expressed haemolysin (67%), aesculinase (65%), gelatinase (62%). Resistance trimethoprim-sulfamethoxazole encoded by sul1 gene 44.83% tet(A) (59.52%). ESBL blaTEM, blaSHV, blaCTX-M detected PCR 16.18%, 2.91%, 0.65% strains, respectively. Additionally, 98.63% carried invA marker, notable positive associations between qnrB, spvC. Conclusions: present findings revealed significant patterns isolates, subtypes, AR, virulence, emphasising need continuous surveillance infections. potential AgNPs an treatment option demonstrated, particularly paediatric S. enterica

Language: Английский

Citations

0
Preparation of glass fiber-PVA assisted secondary growth of silver nanowires and flexible conductive films DOI

Weimin Yan,

Chengmin Hou

Materials Chemistry and Physics, Journal Year: 2025, Volume and Issue: unknown, P. 130685 - 130685

Published: March 1, 2025

Language: Английский

Citations

0
Incorporating zinc coordination driven nanozyme into chitosan and hyaluronic acid based nanoplatform for scavenging H2S/ROS in managing inflammatory bowel disease DOI
Jiafeng Zou, Wenxing Ding, You Chen

et al.

Carbohydrate Polymers, Journal Year: 2025, Volume and Issue: unknown, P. 123501 - 123501

Published: March 1, 2025

Language: Английский

Citations

0
Antibacterial Activity of Ciprofloxacin-Based Carbon Dot@Silver Nanoparticle Composites DOI Creative Commons

Paloma Maria de Sousa Araujo,

Milena Lima Guimarães, André L. Rossi

et al.

ACS Omega, Journal Year: 2025, Volume and Issue: unknown

Published: March 14, 2025

The combined green synthesis of carbon dots (CDs) from the hydrothermal conversion ciprofloxacin and silver nanoparticles (AgNPs) using sodium alginate as a reducing stabilizing agent results in arrangements nanostructures (CD@AgNP composites) with positive surface charge that electrostatically interact Gram-positive Gram-negative bacteria planktonic form also biofilm forms, inhibiting their growth adhesion on surfaces. Outstanding performance for CD-based materials 5-log reduction colony-forming units (CFU/mL) E. coli after 1 h treatment decrease 99.32% consolidated S. aureus. These result intrinsic fluorescence CDs an overall eco-friendly preparation process can be explored disinfection procedures based direct administration sanitizer dispersed aqueous solution. This is justified by adequate antibiotics positively charged composites AgNPs, resulting nanocomposites which prevailing cationic effect facilitates incorporation diffusion into bacterial membrane cells.

Language: Английский

Citations

0
Optimization of the physiochemical synthesis parameters of the Se/CMC nanocomposite: Antibacterial, antioxidant, and anticancer activity DOI

Nidhal Ahmed,

E.M. Abdelrazek,

Hosam I Salaheldin

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 283, P. 137765 - 137765

Published: Nov. 16, 2024

Language: Английский

Citations

1
Xuesanqi ameliorates DSS-induced colitis in mice by mediating gut microbiota dysbiosis and modulating MAPK/ERK/JNK pathway DOI

Qiyuan Su,

Qian Hu,

Songtao Wu

et al.

Natural Products and Bioprospecting, Journal Year: 2024, Volume and Issue: 14(1)

Published: Nov. 30, 2024

Language: Английский

Citations

0