Enhanced bone regeneration using sodium alginate and polyvinyl alcohol incorporating TiO2 nanoparticles composite film for orthopedic application

Results in Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 102049 - 102049

Published: Jan. 1, 2025

Language: Английский

---

Dual release scaffolds as a promising strategy for enhancing bone regeneration: an updated review

Nanomedicine, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 18

Published: Jan. 31, 2025

Advancements in tissue regeneration, particularly bone regeneration is key area of research due to potential novel therapeutic approaches. Efforts reduce reliance on autologous and allogeneic grafts have led the development biomaterials that promote synchronized controlled healing. However, use growth factors limited by their short half-life, slow penetration, large molecular size toxicity. These suggest traditional delivery methods may be inadequate hence, address these challenges, new strategies are being explored. approaches include bioactive substances within advanced systems enable precise spatiotemporal control. Dual-release composite scaffolds offer a promising solution reducing need for multiple surgical interventions simplifying treatment process. allow sustained drug release, enhancing repair while minimizing drawbacks conventional methods. This review explores various dual-drug release systems, discussing modes action, types drugs used mechanisms improve regeneration.

Language: Английский

---

Next-generation solar energy: Progress, stability, and prospects of polymer-modified Perovskite solar cells; A review

International Journal of Hydrogen Energy, Journal Year: 2025, Volume and Issue: 106, P. 1088 - 1113

Published: Feb. 8, 2025

Language: Английский

---

Biomimetic Fabrication and Osteogenic Effects of E7BMP-2 Peptide Coassembly Microspheres Based α-Tricalcium Phosphate with Silk Fibroin

ACS Applied Bio Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 13, 2025

The repair and reconstruction of bone defects remain a challenge in orthopedics. Inadequate mechanical qualities, poor biocompatibility, insufficient osteoconductivity are some the issues facing current healing materials. Better materials that can replicate composition functionality natural bone, promote quick full healing, reduce likelihood rejection infection desperately needed. Bone tissue engineering, combining biomaterial scaffolds pro-osteogenic drugs, provides support regeneration defects. development an effective scaffold for defect is urgent clinical need. present study investigates feasibility using microspheres based on α-tricalcium phosphate fibroin as osteoconductive matrix carrier controlled local delivery E7BMP-2 peptide, which E7 domain confers calcium chelation property, while BMP-2 mimicking peptide induces formation. We prepared phosphate/silk (α-TCP/SF) through high voltage electric field protocol α-TCP/SF cement slurry. This microspheres-based system was designed vehicles modified by to realize sustainable steady release peptide. In vitro cell tests experimental model cranial rats were used investigate benefits. results demonstrated peptide-bound functioned sustained enhanced osteogenic differentiation marrow mesenchymal stem cells rat calvarial Additionally, toxicity studies showed have good biocompatibility safety. Thus, these provide promising therapeutic strategy treatment

Language: Английский

---

Development and characterization of nano-hydroxyapatite/gelatin/PVA/alginate-based multifunctional active scaffolds for bone regeneration: An in vitro and in vivo study

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 141160 - 141160

Published: Feb. 1, 2025

Language: Английский

---

Repurposing Biowaste for Biomedical Applications: Eggshell containing Injectable Bone Substitution Cements for Bone Regeneration

Hybrid Advances, Journal Year: 2025, Volume and Issue: unknown, P. 100425 - 100425

Published: Feb. 1, 2025

Language: Английский

---

Recent Advances in Hydrogel-Based 3D Disease Modeling and Drug Screening Platforms

Advances in experimental medicine and biology, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Language: Английский

---

Effect of Bioactive Glass on PXDDA / PXDDA-co-PLA Nanocomposite for Hard Tissue Reconstruction: Synthesis and Characterization

Journal of Materials Research and Technology, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский

---

3D-Printed PLA/PEG Bone Scaffold: Body-Adaptive Thermally Responsive Shape Memory and Enhanced Biological Performance

Surfaces and Interfaces, Journal Year: 2024, Volume and Issue: unknown, P. 105712 - 105712

Published: Dec. 1, 2024

Language: Английский

---

An Up-to-Date Review of Materials Science Advances in Bone Grafting for Oral and Maxillofacial Pathology

Materials, Journal Year: 2024, Volume and Issue: 17(19), P. 4782 - 4782

Published: Sept. 28, 2024

Bone grafting in oral and maxillofacial surgery has evolved significantly due to developments materials science, offering innovative alternatives for the repair of bone defects. A few grafts are currently used clinical settings, including autografts, xenografts, allografts. However, despite their benefits, they have some challenges, such as limited availability, possibility disease transmission, lack personalization defect. Synthetic gained attention since potential overcome these limitations. Moreover, new technologies like nanotechnology, 3D printing, bioprinting allowed incorporation molecules or substances within aid repair. The addition different moieties, growth factors, stem cells, nanomaterials, been reported help mimic natural healing process more closely, promoting faster complete regeneration. In this regard, review explores available grafts, incorporating into composition accelerate improve regeneration, advanced graft manufacturing techniques. Furthermore, presented current applications success stories novel emphasize future synthetic biomaterial innovations improving patient outcomes surgery.

Language: Английский

---