Utilisation of High Molecular Weight and Ultra-High Molecular Weight Hyaluronan in Management of Glioblastoma

Gels, Journal Year: 2025, Volume and Issue: 11(1), P. 50 - 50

Published: Jan. 8, 2025

HA (hyaluronan) has been considered in recent years as a naturally occurring modifiable gel-like scaffold that the capability to absorb and release drugs over an extended period of time making it suitable potential chemotherapeutic delivery agent. Considering limited treatment options available glioblastoma, this review, we discuss novel utilisation ultra-high molecular weight HA-originally identified mechanism for maintaining longevity naked mole-rat-as both protective extracellular matrix-optimizing colloidal scaffold, means deliver therapy resected brain tumours. The unique properties form cross-linked gel indicate future use prevention proliferative-based inflammation-driven disease.

Language: Английский

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Selenium-copper hyaluronic acid nanoparticles: A novel green synthesis for improved anticancer activity against HepG2 liver cancer cells

Inorganic Chemistry Communications, Journal Year: 2025, Volume and Issue: 173, P. 113869 - 113869

Published: Jan. 5, 2025

Language: Английский

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Chitosan Scaffolds for Drug Delivery

Advances in polymer science, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Language: Английский

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Recent advances of hyaluronic acid‐based materials in drug delivery systems and regenerative medicine: A review

Archiv der Pharmazie, Journal Year: 2025, Volume and Issue: 358(3)

Published: March 1, 2025

Abstract Nowadays, diseases have a high rate of incidence and mortality worldwide. On the other side, drawbacks conventional modalities in suppression encountered serious problematic issues for health human beings. For instance, although various approaches been applied treatment cancer, it has an ever‐increasing throughout globe. Thus, there is fundamental requirement development breakthrough technologies inhibition diseases. Hyaluronic acid (HA) one most practical biopolymers HA lots potential physicochemical (like rheological, structural, molecular weight, ionization, etc.) biomedical properties (bioavailability, biocompatibility, CD44 targeting signaling pathways, components biological organs, mucoadhesion, immunomodulation, etc.), which made candidate tools pharmaceutical sciences. The ease surface modification (carboxylation, amidation, hydroxylation, esterification), bioavailability synthesis routes, administration routes are considered as merits HA‐based vehicles. These mucopolysaccharide materials considerably developed use drug delivery systems (DDSs), cancer therapy, wound healing, antiaging, tissue engineering. This review summarizes advantages DDS scaffolds

Language: Английский

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Nanotechnology-based drug delivery for breast cancer treatment: Current applications and future directions

European Journal of Medicinal Chemistry Reports, Journal Year: 2025, Volume and Issue: unknown, P. 100268 - 100268

Published: April 1, 2025

Language: Английский

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Performance evaluation of ciprofloxacin loaded curcumin-exopolysaccharide bioconjugate carrier for eradication of bacterial biofilms

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 142946 - 142946

Published: April 1, 2025

Language: Английский

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Marine polysaccharides for antibiofilm application: A focus on biomedical fields

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 137786 - 137786

Published: Nov. 1, 2024

Language: Английский

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