Polymers for Advanced Technologies, Journal Year: 2025, Volume and Issue: 36(5)

Published: May 1, 2025

ABSTRACT Nanofiber‐based drug delivery systems show strong potential due to their high surface area‐to‐volume ratio and adjustable structure. Recent studies demonstrated loading efficiencies exceeding 85%, with sustained release kinetics up 96 h. In cancer models, nanofiber‐based carriers improved accumulation at tumor sites by 3–4 fold compared conventional formulations, enhancing therapeutic efficacy minimizing systemic toxicity. This review outlines methods for precise nanofiber shape function control through electrospinning solution blow spinning techniques. advancements in technology have proven promising biomedical applications where they are utilized tissue engineering, neurodegenerative disease management, wound healing, targeted therapy. Nanofibers as an optimal system that improves cellular restoration, together controlled deep penetration capabilities. The recent development of dual‐drug systems, stimuli‐responsive nanofibers, scaffolds composed nanofibers smart materials has expanded usage precision medicine. Research now demonstrates facilitate remodeling functions along angiogenesis promotion, inflammatory response stability improvement. also focuses on the patents a system. addition, this presents new approaches overcome these challenges based interdisciplinary cooperation, AI‐driven design such sophisticated bioinformatics tools. review, advances prospects realizing revolution field improving healthcare outcomes presented detailed overview.

Language: Английский