Advances in the study of polysaccharide-based hydrogel wound dressings

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 142134 - 142134

Published: March 1, 2025

Language: Английский

High-Level Lanthanide-Doped Upconversion Nanoparticles-Based Aptasensor to Increase Carcinoembryonic Antigen Detection Sensitivity

Materials, Journal Year: 2025, Volume and Issue: 18(4), P. 796 - 796

Published: Feb. 11, 2025

Boosting the accuracy and speed of cancer detection is highly desirous in tumor detection, sensors capable detecting carcinoembryonic antigen (CEA) have great application prospects this field. A sensitive sensor constructed based on fluorescence resonance energy transfer (FRET) with heavily rare-earth-doped upconversion nanoparticles (UCNPs) as donors polydopamine (PDA NPs) acceptors. This detects fluctuations CEA molecules via luminescence quenching recovery resulting from a competitive binding assay between PDA NPs. The high-level-doped design UCNPs (i.e., NaYF4@NaYbF4:1%Tm@NaYF4) beneficial, providing intensity that more than 10 times higher conventional low-level-doped NaYF4@NaYF4:20%Yb, 0.2%Tm@NaYF4). exhibits impressive sensitivity. Specifically, diluted fetal bovine serum, limit reaches 0.013 ng/mL range 0–1.5 (S/N = 3), while 1.38 1.5–250 3). method has potential for future applications rapid early diagnosis treatment cancer.

Language: Английский

Acid-responsive contractile hyaluronic acid-based hydrogel loaded with ginsenoside Rg1 for hemostasis and promotion of gastric wound healing

Biomaterials, Journal Year: 2025, Volume and Issue: 321, P. 123320 - 123320

Published: April 5, 2025

Language: Английский