Steam-exploded Dictyophora indusiata polysaccharide regulated gut microbiota based on dynamic in vitro stomach-intestine digestion system DOI

Zhikun Zeng,

Haihui Huang, Lin Wang

et al.

Food Bioscience, Journal Year: 2024, Volume and Issue: 62, P. 105470 - 105470

Published: Nov. 14, 2024

Language: Английский

Investigating the Alleviating Effect of Fucoidan from Apostichopus japonicus on Ulcerative Colitis by Mice Experiments and In Vitro Simulation of Human Fecal Fermentation DOI Creative Commons

Lingyan Xue,

Yuchen Huan,

Yaoguang Chang

et al.

Foods, Journal Year: 2025, Volume and Issue: 14(4), P. 574 - 574

Published: Feb. 9, 2025

Fucoidan from Apostichopus japonicus (Aj-FUC) is a marine polysaccharide extracted the high-quality sea cucumber, which has received increasing attention for its multiple biological activities. In this study, Aj-FUC was extracted, and basic structure characterized, while alleviating efficacy of on ulcerative colitis (UC) investigated using C57BL/6 mice. The improvement fecal gut microbiota in healthy individuals inflammatory bowel disease (IBD) patients explored vitro simulated fermentation. results reflected that treatment attenuated histopathological damage associated with colitis, reduced levels IL-6, IL-1β, TNF-α. also upregulated expression ZO-1 occludin, thereby aiding repair intestinal barrier. Furthermore, enhanced short-chain fatty acids (SCFAs) helped restore balance microbiota, particularly by relative abundance Akkermansia. simulation fermentation showed could modulate IBD increase beneficial bacteria. conclusion, study highlights can alleviate UC modulating factors, improving barrier, regulating flora variety ways.

Language: Английский

Citations

1
Anti-inflammation and intestinal flora modulation ability of Moutan Cortex polysaccharide and its interaction with soybean protein isolate DOI
Yuxin Wen,

Wenbing Yan,

Ming Liu

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 142785 - 142785

Published: April 1, 2025

Language: Английский

Citations

0
Construction and dynamic in vitro digestive characteristics of whey protein/chlorogenic acid/high methoxy pectin water-in-oil-in-water emulsion DOI
Qinqiu Zhang, Yi Xu, Jingming Li

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 309, P. 142956 - 142956

Published: April 12, 2025

Language: Английский

Citations

0
Differences in structure, antioxidant capacity and gut microbiota modulation of red raspberry pectic polysaccharides extracted by different methods DOI
You Luo,

Ruling Tang,

Yongguang Huang

et al.

Food Research International, Journal Year: 2025, Volume and Issue: unknown, P. 116474 - 116474

Published: April 1, 2025

Language: Английский

Citations

0
Steam-exploded Dictyophora indusiata polysaccharide regulated gut microbiota based on dynamic in vitro stomach-intestine digestion system DOI

Zhikun Zeng,

Haihui Huang, Lin Wang

et al.

Food Bioscience, Journal Year: 2024, Volume and Issue: 62, P. 105470 - 105470

Published: Nov. 14, 2024

Language: Английский

Citations

1