Structure–Antioxidant Activity Relationship of Polysaccharides Isolated by Microwave/Ultrasonic-Assisted Extraction from Pleurotus ferulae

Antioxidants, Journal Year: 2025, Volume and Issue: 14(1), P. 91 - 91

Published: Jan. 14, 2025

To investigate the structure-antioxidant activity relationship, Pleurotus ferulae polysaccharides were extracted using ultrasonic (U-PFPS) and microwave/ultrasonic-assisted methods (MU-PFPS). Compared to U-PFPS with a molecular weight of 1.566 × 103 kDa, MU-PFPS exhibited lower 89.26 kDa. In addition, unlike U-PFPS, which is primarily composed glucose (Glu:Man:Gal = 91.1:3.5:5.4), has more balanced composition Glu:Man:Gal in ratio 39.4:27.8:32.8 contains branched chains. Furthermore, antioxidant analysis revealed that high concentration (at concentrations above 600 μg/mL) demonstrated stronger protective effects against oxidative damage RAW264.7 cells than did. Collectively, these data suggest higher branching degree at appropriate may correlate enhanced enzyme activities. Our work provides method for isolating offers insights into structure-activity relationship polysaccharides, laying foundation future applications polysaccharide modification structural characterization.

Language: Английский

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The application of traditional Chinese medicine polysaccharides in wound healing: A review

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 304, P. 140993 - 140993

Published: Feb. 12, 2025

Language: Английский

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Integrated metabolomics and intestinal microbiota analysis to reveal anti-post-weaning diarrhea mechanisms of Modified Yupingfeng Granule in Rex rabbits

Frontiers in Microbiology, Journal Year: 2025, Volume and Issue: 16

Published: April 10, 2025

Post-weaning Diarrhea (PWD) is a kind of physiological stress diarrhea in Rex rabbits after weaning, which can lead to death severe cases. Traditional Chinese medicine (TCM) has been widely used animal due its advantages natural origin, diverse functions, safety, reliability, economy and environmental protection. Modified Yupingfeng Granule (MYPFG) an improved prescription based on the famous traditional (YPF), combined with other TCM obvious synergistic additive activity order obtain excellent for PWD. In this study, 120 weaned were randomly allocated 4 treatment groups, including control (CON), low dose (LD), medium (MD), high (HD). Rabbits fed diet or different MYPFG proportions 30 days. The study 16S rRNA analysis intestinal microbiota cecal contents metabolomics explore effect rabbits. increased average daily gain, villus length crypt depth ratio decreased feed meat ratio, frequency, mortality rate, (p < 0.05). test found that could change abundances Patescibacteria, Sphingobium, Ruminococcus, Oxalobacter. Metabolomics may be related regulation Glycine, serine threonine metabolism, Arginine proline metabolism. Nicotinate nicotinamide regulate metabolic pathway some amino acids alleviate PWD

Language: Английский

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Determination of the Composition and Monosaccharide Content of Atractylodes Polysaccharides Using Pre-column Derivatization and a Quantitative Analysis of Multicomponents by a Single Marker Method

Journal of Chromatography Open, Journal Year: 2025, Volume and Issue: unknown, P. 100224 - 100224

Published: May 1, 2025

Language: Английский

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Structural characterization and effect of activating autophagy and regulating oxidative stress of polysaccharide from fibrous roots of Atractylodes chinensis

Bioorganic Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 108609 - 108609

Published: May 1, 2025

Language: Английский

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