From Emergence to Evolution: Dynamics of the SARS-CoV-2 Omicron Variant in Florida DOI Creative Commons
Sobur Ali, Marta Giovanetti, Catherine Johnston

et al.

Pathogens, Journal Year: 2024, Volume and Issue: 13(12), P. 1095 - 1095

Published: Dec. 12, 2024

The continual evolution of SARS-CoV-2 has significantly influenced the global response to COVID-19 pandemic, with emergence highly transmissible and immune-evasive variants posing persistent challenges. Omicron variant, first identified in November 2021, rapidly replaced Delta becoming predominant strain worldwide. In Florida, was detected December leading an unprecedented surge cases that surpassed all prior waves, despite extensive vaccination efforts. This study investigates molecular transmission dynamics lineages during Florida’s supported by a robust dataset over 1000 sequenced genomes. Through phylogenetic phylodynamic analyses, we capture rapid diversification lineages, identifying significant importation events, predominantly from California, Texas, New York, exportation North America, Europe, South America. Variants such as BA.1, BA.2, BA.4, BA.5 exhibited distinct patterns, BA.2 showing ability reinfect individuals previously infected BA.1. Despite high transmissibility immune evasion sub-lineages, plateauing late 2022 suggests increasing population immunity infection vaccination. Our findings underscore importance continuous genomic surveillance variant introductions, mapping pathways, guiding public health interventions mitigate current future pandemic risks.

Language: Английский

Epidemiological Transitions in Influenza Dynamics in the United States: Insights from Recent Pandemic Challenges DOI Creative Commons
Marta Giovanetti, Sobur Ali, Svetoslav Nanev Slavov

et al.

Microorganisms, Journal Year: 2025, Volume and Issue: 13(3), P. 469 - 469

Published: Feb. 20, 2025

The SARS-CoV-2 pandemic has reshaped the epidemiological landscape of respiratory diseases, with profound implications for seasonal influenza. Nonpharmaceutical interventions implemented globally during significantly altered human behavior and reduced prevalence pathogens, including However, post-pandemic resurgence influenza activity to pre-pandemic levels highlights persistent challenges posed by this virus. During 2023–2024 season in United States, an estimated 40 million individuals contracted influenza, resulting 470,000 hospitalizations 28,000 deaths, elderly disproportionately affected. Pediatric mortality was also notable, 724 deaths reported among children. This study examines trends incidence, vaccination rates, States from 2018–2019 through seasons. Additionally, it evaluates interplay between pandemic, considering impact disrupted air travel, public health measures, virus circulation dynamics. By integrating these insights, underscores critical need sustained campaigns innovative strategies mitigate dual burden diseases. Findings analysis highlight urgency strengthening prevention surveillance systems enhance preparedness reduce pathogens evolving landscape.

Language: Английский

Citations

0
Managing epidemics in the digital age: the crucial role of social media in information dissemination DOI
Francesco Branda, Massimo Ciccozzi, Fabio Scarpa

et al.

Pathogens and Global Health, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 7

Published: April 15, 2025

Language: Английский

Citations

0
From Emergence to Evolution: Dynamics of the SARS-CoV-2 Omicron Variant in Florida DOI Creative Commons
Sobur Ali, Marta Giovanetti, Catherine Johnston

et al.

Pathogens, Journal Year: 2024, Volume and Issue: 13(12), P. 1095 - 1095

Published: Dec. 12, 2024

The continual evolution of SARS-CoV-2 has significantly influenced the global response to COVID-19 pandemic, with emergence highly transmissible and immune-evasive variants posing persistent challenges. Omicron variant, first identified in November 2021, rapidly replaced Delta becoming predominant strain worldwide. In Florida, was detected December leading an unprecedented surge cases that surpassed all prior waves, despite extensive vaccination efforts. This study investigates molecular transmission dynamics lineages during Florida’s supported by a robust dataset over 1000 sequenced genomes. Through phylogenetic phylodynamic analyses, we capture rapid diversification lineages, identifying significant importation events, predominantly from California, Texas, New York, exportation North America, Europe, South America. Variants such as BA.1, BA.2, BA.4, BA.5 exhibited distinct patterns, BA.2 showing ability reinfect individuals previously infected BA.1. Despite high transmissibility immune evasion sub-lineages, plateauing late 2022 suggests increasing population immunity infection vaccination. Our findings underscore importance continuous genomic surveillance variant introductions, mapping pathways, guiding public health interventions mitigate current future pandemic risks.

Language: Английский

Citations

1