Systematic Development of PPY/GO/ZnO Hybrid Composite for Electrochemical Detection of Pb2+ in Aqueous Solution DOI Creative Commons

Goverdhan Singh,

Nisha Gupta, Anil Kumar

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 7, 2024

Abstract The accumulation of heavy metals in water sources at levels exceeding acceptable limits poses a serious risk to human health and the environment. Various electrochemical methods electroactive materials have been employed identify measure these metal ions. However effective, low-cost, sensitive, stability, with low detection limit high reproducibility, is major requirement such sensing materials. In this regard, an enhanced hybrid ternary composite PGT based on polypyrrole, GO, ZnO (PPY/GO/ZnO) has fabricated reportedly being used for first time lead (Pb2+) ions trace level aqueous solutions. was characterized using Fourier transform-infrared spectroscopy (FTIR), X-ray diffraction (XRD), Thermogravimetric analysis (TGA) study its structural, morphological, thermal properties. response material analyzed Cyclic voltammetry (CV) Electron impedance (EIS) potassium ferricyanide as redox probe. sensitivity, selectivity, reproducibility were studied via differential pulse anodic stripping (DPASV) technique. electrode shows good linear (R2 = ~ 0.98) 0.05 µM Pb2+ within concentration range 0.3 3 µM. RSD (1.089%), stability (3.67%), interference working presence other (Cd2+ Cu2+) show response. These results represent possibilities employing effectively detect from sources.

Language: Английский

Systematic development of PPY/GO/ZnO hybrid composite for electrochemical detection of Pb2+ in aqueous solution DOI

Goverdhan Singh,

Nisha Gupta, Anil Kumar

et al.

Ionics, Journal Year: 2025, Volume and Issue: 31(3), P. 3105 - 3119

Published: Jan. 11, 2025

Language: Английский

Citations

2
Green Synthesis of Biomass-Derived Porous Carbon for Electrochemical Detection of Heavy Metal Ions: Methods, Properties, and Applications DOI
Bo Zhang,

Gangxin Ren,

Linghao Ran

et al.

Journal of environmental chemical engineering, Journal Year: 2024, Volume and Issue: 12(5), P. 113903 - 113903

Published: Aug. 23, 2024

Language: Английский

Citations

13
Breakthroughs in nanostructured-based chemical sensors for the detection of toxic metals DOI Creative Commons

Tinsae F. Gezahegn,

Abera Demeke Ambaye,

Tewolde M. Mekoyete

et al.

Talanta Open, Journal Year: 2024, Volume and Issue: 10, P. 100354 - 100354

Published: Sept. 10, 2024

Language: Английский

Citations

8
Exploring Fluorescence Spectral Shifts in Aptamer-Intercalating Cyanine Dye Complexes upon Binding to Specific Small Molecules DOI
Yasmin Liu, Onyekachi Raymond, Justin M. Hodgkiss

et al.

ACS Sensors, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 25, 2025

DNA intercalating cyanine dyes, such as SYBR Green I (SG) and OliGreen (OG), are widely used in developing label-free, fluorescent aptamer-based biosensors. Despite their widespread use for direct analyte detection through changes fluorescence intensity, the effects of dye concentrations specific nature interactions have been inadequately explored. Here, we reported how dye-to-base ratios (dbrs) influence response dyes aptamer systems targeting adenosine triphosphate (ATP) l-argininamide (LAA). We initially examined spectral shifts an ATP (ABA) with SG across varying dbrs, observing emission shift to longer wavelengths dbrs increased. Subsequently, systematic analysis complex (ABA/SG) at different target revealed a "signal-off" phenomenon very low dbr 0.1, which transitioned blue spectra higher values 0.7 2.0. Further extending our research, explored OG ratiometric probe detecting l-argininamide, noting similar shorter upon binding. Absorption spectroscopy, circular dichroism (CD), meticulously designed control studies were employed elucidate comprehensively. Our findings underscore significant impact selection concentration on performance aptasensors demonstrate that clear shifts, indicative binding, occur binding targets, particularly loading; however, excessive can perturb structure, reducing its affinity. believe will provide new insights into designing assays sensitive small molecules.

Language: Английский

Citations

0
MOF-Derived N-Doped Carbon Nanotube-Confined Ni Nanoparticles for the Simultaneous Electrochemical Detection of Cu²⁺ and Hg²⁺ with High Sensitivity and Stability DOI Creative Commons
Jiapeng Li, Lili Chen, Yiming Qiao

et al.

Molecules, Journal Year: 2025, Volume and Issue: 30(5), P. 1078 - 1078

Published: Feb. 26, 2025

Heavy metal pollution has posed a serious threat to the ecological environment and human health. Thus, development of accurate effective methods for their detection is crucial. In this study, novel electrochemical sensor was fabricated detect Cu2+ Hg2+, based on N-doped carbon nanotube-wrapped Ni nanoparticle (Ni@N-CNT) sensing material, which derived from pyrolysis Ni2+ doped ZIF-8. For electrode material design, packaging structure not only protected encapsulated nanoparticles corrosion in acid electrolyte but also provided excellent electro-catalytic activity electrical conductivity by controlling size. Thanks overall performance Ni@N-CNT composite, proposed exhibited analytical Hg2+ detection, with ultra-low limits 33.3 ng⋅L-1 ng⋅L-1, respectively. The demonstrated good repeatability, reproducibility selectivity. addition, method successfully applied analysis actual Chinese cabbage samples satisfactory recovery, confirming its practical applicability.

Language: Английский

Citations

0
Single-Use Electrochemical Aptamer-Based Sensors for Calibration-Free Measurements in Human Saliva via Dual-Frequency Approaches: Prospects and Challenges DOI
Yasmin Liu, Rishi Ranjan Pandey, Mary Jane McCarthy

et al.

Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 26, 2025

Despite the rapid growth in aptamer-based biosensor research, there remains a significant demand for aptasensors that operate without need sample preparation and calibration, to better facilitate real-world applications. Electrochemical (EAB) sensors, particularly those utilizing dual-frequency, calibration-free approach, have shown promising advances toward commercialization. Single-use, disposable sensors represent cost-effective solution at-home on-site point-of-care (POC) diagnostics. However, development of these presents unique challenges compared vivo monitoring reusable platforms, with pronounced variations across batches. Motivated by challenges, we comprehensively investigated focusing on sensor-to-sensor batch-to-batch variations. Our research explored use nonresponsive frequency-based ratiometric method detecting cocaine laser-ablated, EAB sensors. Additionally, overcome absence frequencies some aptasensors, developed strategies modify aptamer structure optimize operational conditions, effectively tailoring allow result turnover. Moreover, assessed effects various filter types saliva pretreatment using liquid chromatography tandem mass spectrometry (LCMS/MS) collection workflow an oral swab. This herein achieved low μM sensitivity saliva, results obtainable under 5 min, including processing. Furthermore, our findings indicate certain food drink residues can compromise sensor accuracy, highlighting area future refinement.

Language: Английский

Citations

0
Systematic Development of PPY/GO/ZnO Hybrid Composite for Electrochemical Detection of Pb2+ in Aqueous Solution DOI Creative Commons

Goverdhan Singh,

Nisha Gupta, Anil Kumar

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 7, 2024

Abstract The accumulation of heavy metals in water sources at levels exceeding acceptable limits poses a serious risk to human health and the environment. Various electrochemical methods electroactive materials have been employed identify measure these metal ions. However effective, low-cost, sensitive, stability, with low detection limit high reproducibility, is major requirement such sensing materials. In this regard, an enhanced hybrid ternary composite PGT based on polypyrrole, GO, ZnO (PPY/GO/ZnO) has fabricated reportedly being used for first time lead (Pb2+) ions trace level aqueous solutions. was characterized using Fourier transform-infrared spectroscopy (FTIR), X-ray diffraction (XRD), Thermogravimetric analysis (TGA) study its structural, morphological, thermal properties. response material analyzed Cyclic voltammetry (CV) Electron impedance (EIS) potassium ferricyanide as redox probe. sensitivity, selectivity, reproducibility were studied via differential pulse anodic stripping (DPASV) technique. electrode shows good linear (R2 = ~ 0.98) 0.05 µM Pb2+ within concentration range 0.3 3 µM. RSD (1.089%), stability (3.67%), interference working presence other (Cd2+ Cu2+) show response. These results represent possibilities employing effectively detect from sources.

Language: Английский

Citations

0