Functionalized Triangular Carbon Quantum Dot Stabilized Gold Nanoparticles Decorated Boron Nitride Nanosheets Interfaced for Electrochemical Detection of Cardiac Troponin T DOI
So Eun Kim, Jae Chol Yoon, Alagan Muthurasu

et al.

Langmuir, Journal Year: 2024, Volume and Issue: 40(47), P. 25051 - 25060

Published: Nov. 12, 2024

The fast, and highly sensitive estimation of cardiac troponin T (cTnT) is crucial for the early identification acute myocardial infarction (AMI). electrochemical immunoassay-based (EIB) sensors are promising this purpose, as they offer precise measurements can be directly assessed in intricate matrices, including blood. To increase sensitivity, EIB use nanomaterials or amplification processes, which laborious to develop. With this, we develop an immunosensor detection (cTnT). sensing platform composed functionalized triangular carbon quantum dots stabilized gold nanoparticles integrated with boron nitride nanosheets (caf-TCQDs@AuNPs on HO-BNNS). Ferrocene carboxylic acid (Fc-COOH) serves signal label. composite was developed examined using several techniques such X-ray diffraction (XRD), photoelectron spectroscopy (XPS), transmission electron microscopy (TEM), cyclic voltammetry, chronocoulometry. caf-TCQDs@AuNPs supported HO-BNNS, have a large surface area excellent electrical conductivity, serve effective immobilization anti-cTnT monoclonal antibodies via carbodiimide coupling. Fc-COOH, functioning label through oxidation process, HO-BNNS establish cTnT. demonstrated performance determination cTnT under optimal conditions, exhibiting linearity range spanning from 0.0001 100 ng mL

Language: Английский

Analysis of Personalized Cardiovascular Drug Therapy: From Monitoring Technologies to Data Integration and Future Perspectives DOI Creative Commons

Runxing Lin,

Ziyu Huang, Yu Liu

et al.

Biosensors, Journal Year: 2025, Volume and Issue: 15(3), P. 191 - 191

Published: March 17, 2025

Cardiovascular diseases have long been a major challenge to human health, and the treatment differences caused by individual variability remain unresolved. In recent years, personalized cardiovascular drug therapy has attracted widespread attention. This paper reviews strategies for achieving through traditional dynamic monitoring multidimensional data integration analysis. It focuses on key technologies monitoring, based differences, By systematically reviewing relevant literature, main challenges in current research proposed potential directions future studies were summarized.

Language: Английский

Citations

0
Recent advances in MOF-modified electrochemical sensor for point-of-care detecting cardiac biomarkers DOI
Mohamed Ahmed, Jingyi Bai, Lingxue Kong

et al.

TrAC Trends in Analytical Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 118277 - 118277

Published: April 1, 2025

Language: Английский

Citations

0
Functionalized Triangular Carbon Quantum Dot Stabilized Gold Nanoparticles Decorated Boron Nitride Nanosheets Interfaced for Electrochemical Detection of Cardiac Troponin T DOI
So Eun Kim, Jae Chol Yoon, Alagan Muthurasu

et al.

Langmuir, Journal Year: 2024, Volume and Issue: 40(47), P. 25051 - 25060

Published: Nov. 12, 2024

The fast, and highly sensitive estimation of cardiac troponin T (cTnT) is crucial for the early identification acute myocardial infarction (AMI). electrochemical immunoassay-based (EIB) sensors are promising this purpose, as they offer precise measurements can be directly assessed in intricate matrices, including blood. To increase sensitivity, EIB use nanomaterials or amplification processes, which laborious to develop. With this, we develop an immunosensor detection (cTnT). sensing platform composed functionalized triangular carbon quantum dots stabilized gold nanoparticles integrated with boron nitride nanosheets (caf-TCQDs@AuNPs on HO-BNNS). Ferrocene carboxylic acid (Fc-COOH) serves signal label. composite was developed examined using several techniques such X-ray diffraction (XRD), photoelectron spectroscopy (XPS), transmission electron microscopy (TEM), cyclic voltammetry, chronocoulometry. caf-TCQDs@AuNPs supported HO-BNNS, have a large surface area excellent electrical conductivity, serve effective immobilization anti-cTnT monoclonal antibodies via carbodiimide coupling. Fc-COOH, functioning label through oxidation process, HO-BNNS establish cTnT. demonstrated performance determination cTnT under optimal conditions, exhibiting linearity range spanning from 0.0001 100 ng mL

Language: Английский

Citations

0