Inflammatory Cell-Targeted Delivery Systems for Myocardial Infarction Treatment

Bioengineering, Journal Year: 2025, Volume and Issue: 12(2), P. 205 - 205

Published: Feb. 19, 2025

Myocardial infarction (MI) is a cardiovascular disease (CVD) with high morbidity and mortality worldwide, which serious threat to human life health. Inflammatory immune responses are initiated immediately after MI, unbalanced inflammation post-MI can lead cardiac dysfunction, scarring, ventricular remodeling, emphasizing the critical need for an effective inflammation-regulating treatment. With development of novel therapies, drug delivery system specific inflammatory cells offers significant potential. In this review, we introduce fibroblasts involved in MI summarize newly developed systems related use injectable hydrogels, patches, nanoparticles, extracellular vesicles (EVs). Finally, highlight recent trends cell-targeting involving different strategies that facilitate treatment MI.

Language: Английский

Anthracycline-induced cardiotoxicity: emerging mechanisms and therapies

Medicine Plus, Journal Year: 2025, Volume and Issue: unknown, P. 100074 - 100074

Published: Feb. 1, 2025

Language: Английский