Trends, key contributors, and emerging issues in honey and breast cancer: A bibliometric analysis from 2014 to 2024 DOI Creative Commons
Andi Nilawati Usman, Fendi Fendi, Zafitri Nulandari

et al.

F1000Research, Journal Year: 2025, Volume and Issue: 14, P. 17 - 17

Published: March 24, 2025

Background Honey, a natural product with diverse bioactive compounds, has been increasingly explored for its potential anticancer properties. This study aims to comprehensively analyze the scientific literature on relationship between honey and breast cancer. Methods A bibliometric analysis was conducted using ScienceDirect database identify publications from 2014 2024. Data publication trends, author collaboration, keyword were extracted gain insight into research landscape. Keyword identified nine distinct clusters, indicating directions regarding role of in cancer treatment. Results In Key journals such as Journal Ethnopharmacology Food Chemistry have at forefront disseminating findings this domain, demonstrating strongly interdisciplinary approach that bridges traditional medicine modern inquiry. The increasing interest properties honey, evidenced by growing number studies, underlines promising agent prevention Conclusions provides comprehensive overview current knowledge landscape highlights emerging issues require further exploration.

Language: Английский

Protective effects and mechanisms of quercetin in animal models of hyperuricemia: A systematic review and meta-analysis DOI Creative Commons

Xueren Bian,

Z. K. Ge,

Xu-Shan Chen

et al.

Pharmacological Research, Journal Year: 2025, Volume and Issue: unknown, P. 107665 - 107665

Published: Feb. 1, 2025

Quercetin, a prevalent natural flavonoid found in various medicinal plants, including Dendrobium officinale Kimura & Migo, has garnered attention for its potential health benefits. However, foundational animal studies investigating the effects of quercetin on lowering uric acid levels remain insufficiently established, and number related clinical is limited. This scarcity hinders practical application managing hyperuricemia. We systematically searched preclinical published by December 2024 nine databases, such as PubMed, Web Science, Embase. The results our meta-analysis showed that, compared with model group, not only effectively alleviated pathological injury kidney liver improved renal function indexes hyperuricemia but also played role modulating multiple signaling pathways oxidative stress, lipid metabolism, transporter proteins. Quercetin more substantial effect decreasing serum creatinine (SMD = -4.29, 95% CI [-6.48, -2.10], P 0.0001), blood urea nitrogen -3.08, [-4.80, -1.35], 0.0005), Up-regulate organic anion 1 mRNA expression 2.72, 95%CI [0.45, 4.99], 0.02) to positive control group. Sensitivity analyses confirmed stability results, while subgroup analysis indicates that treatment course may be main source heterogeneity. Dose-efficacy suggested had protective against at gavage dose 100 - 200mg/kg. accurately assess hyperuricemia, it essential conduct additional high-quality, large-scale trials validate findings.

Language: Английский

Citations

1
Trends, key contributors, and emerging issues in honey and breast cancer: A bibliometric analysis from 2014 to 2024 DOI Creative Commons
Andi Nilawati Usman, Fendi Fendi, Zafitri Nulandari

et al.

F1000Research, Journal Year: 2025, Volume and Issue: 14, P. 17 - 17

Published: Jan. 3, 2025

Background Honey, a natural product with diverse bioactive compounds, has been increasingly explored for its potential anticancer properties. This study aims to comprehensively analyze the scientific literature on relationship between honey and breast cancer. Methods A bibliometric analysis was conducted using ScienceDirect database identify publications from 2014 2024. Data publication trends, author collaboration, keyword were extracted gain insight into research landscape. Keyword identified nine distinct clusters, indicating directions regarding role of in cancer treatment. Results Key journals such as Journal Ethnopharmacology Food Chemistry have at forefront disseminating findings this domain, demonstrating strong interdisciplinary approach that bridges traditional medicine modern inquiry. The increasing interest properties honey, evidenced by growing number studies, underlines promising agent prevention Recent advances synthesis theranostic paradigms cerium oxide nanoparticles (CeONPs) highlighted, well selenium nanoconstructs. toxicity quality control Perillae Fructus also highlighted. Conclusions provides comprehensive overview current state knowledge uncovers emerging issues require further investigation.

Language: Английский

Citations

0
Trends, key contributors, and emerging issues in honey and breast cancer: A bibliometric analysis from 2014 to 2024 DOI Creative Commons
Andi Nilawati Usman, Fendi Fendi, Zafitri Nulandari

et al.

F1000Research, Journal Year: 2025, Volume and Issue: 14, P. 17 - 17

Published: Jan. 20, 2025

Background Honey, a natural product with diverse bioactive compounds, has been increasingly explored for its potential anticancer properties. This study aims to comprehensively analyze the scientific literature on relationship between honey and breast cancer. Methods A bibliometric analysis was conducted using ScienceDirect database identify publications from 2014 2024. Data publication trends, author collaboration, keyword were extracted gain insight into research landscape. Keyword identified nine distinct clusters, indicating directions regarding role of in cancer treatment. Results Key journals such as Journal Ethnopharmacology Food Chemistry have at forefront disseminating findings this domain, demonstrating strong interdisciplinary approach that bridges traditional medicine modern inquiry. The increasing interest properties honey, evidenced by growing number studies, underlines promising agent prevention Recent advances synthesis theranostic paradigms cerium oxide nanoparticles (CeONPs) highlighted, well selenium nanoconstructs. toxicity quality control Perillae Fructus also highlighted. Conclusions provides comprehensive overview current state knowledge uncovers emerging issues require further investigation.

Language: Английский

Citations

0
Nanoparticle-Based Delivery Systems for Phytochemicals in Cancer Therapy: Molecular Mechanisms, Clinical Evidence, and Emerging Trends DOI
Mahmoud A.H. Mostafa, Hani M. J. Khojah

Drug Development and Industrial Pharmacy, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 31

Published: March 21, 2025

This review examines recent advancements in nanoparticle-based delivery systems for phytochemicals, focusing on their role overcoming multidrug resistance, improving therapeutic efficacy, and facilitating clinical translation. highlights advances nanoparticle-enabled phytochemical to enhance bioavailability, improve outcomes, enable targeted applications. By comparing various nanoparticle systems, formulation methods, efficacy data, it identifies gaps current research guides the development of more effective, next-generation phytochemical-loaded nanocarriers. A systematic literature published between 2000 2024 was conducted using PubMed, Scopus, Web Science. Articles cancer therapy were included. Compounds such as curcumin, resveratrol, quercetin, epigallocatechin gallate demonstrate enhanced anti-cancer when encapsulated nanoparticles, leading improved increased tumor cell targeting, reduced toxicity. Clinical trials indicate regression fewer adverse effects. Emerging approaches-such nanogels, hybrid combination therapies with immune checkpoint inhibitors-further refine treatment efficacy. Nanoparticle-based significantly potential making them promising candidates safer, effective treatments. However, challenges related regulatory guidelines, scalability, long-term safety must be addressed fully realize potential.

Language: Английский

Citations

0
Trends, key contributors, and emerging issues in honey and breast cancer: A bibliometric analysis from 2014 to 2024 DOI Creative Commons
Andi Nilawati Usman, Fendi Fendi, Zafitri Nulandari

et al.

F1000Research, Journal Year: 2025, Volume and Issue: 14, P. 17 - 17

Published: March 24, 2025

Background Honey, a natural product with diverse bioactive compounds, has been increasingly explored for its potential anticancer properties. This study aims to comprehensively analyze the scientific literature on relationship between honey and breast cancer. Methods A bibliometric analysis was conducted using ScienceDirect database identify publications from 2014 2024. Data publication trends, author collaboration, keyword were extracted gain insight into research landscape. Keyword identified nine distinct clusters, indicating directions regarding role of in cancer treatment. Results In Key journals such as Journal Ethnopharmacology Food Chemistry have at forefront disseminating findings this domain, demonstrating strongly interdisciplinary approach that bridges traditional medicine modern inquiry. The increasing interest properties honey, evidenced by growing number studies, underlines promising agent prevention Conclusions provides comprehensive overview current knowledge landscape highlights emerging issues require further exploration.

Language: Английский

Citations

0