Nanoformulations Loaded with Phytochemicals for Combating Wound Infections and Promoting Wound Healing: Current Applications and Innovations DOI Creative Commons
Panoraia I. Siafaka, Αndroulla N. Miliotou, Mehmet Evren Okur

et al.

Applied Sciences, Journal Year: 2025, Volume and Issue: 15(10), P. 5413 - 5413

Published: May 12, 2025

Wounds are broadly classified into acute and chronic types, with wounds being those that cannot heal within 4 to 12 weeks despite treatment. There is a growing interest in efficient cost-effective wound healing though the drug delivery of active molecules. Natural compounds such as phytochemicals, well synthetic molecules antimicrobial or anti-inflammatory growth factors, can impact tissue regeneration prevent infections. Nanotechnology-based systems, polymeric inorganic nanoparticles electrospun nanofibrous matrices loaded enhance therapeutic efficacy through improved bioavailability targeted delivery. This review summarizes most current advanced applications combining phytochemicals nanoformulations promising potential. Various nanosystems have been identified, silver nanocarriers, zein-based nanoparticles, various known polymers, which be utilized develop fibrous structures phytoremedies. Despite incorporation these remedies traditional medicine for long time, further clinical studies essential determine their pharmacological properties, safety concerns, efficacy.

Language: Английский

Hydrogels for Wound Dressings: Applications in Burn Treatment and Chronic Wound Care DOI Open Access

A. S. Alberts,

Elena-Theodora Moldoveanu,

Adelina-Gabriela Niculescu

et al.

Journal of Composites Science, Journal Year: 2025, Volume and Issue: 9(3), P. 133 - 133

Published: March 13, 2025

Severe skin injuries such as burns and chronic wounds are a subject of interest in the medical field, they require much attention. These types susceptible to serious complications, which can worsen health patients reduce their quality life. Hydrogels have emerged innovative wound dressings for treating acute wounds, including burns, diabetic foot ulcers, venous leg pressure ulcers. polymeric networks provide moist environment, promote cellular migration, offer antimicrobial properties, being recognized superior conventional dressings. This review aims explore recent advancements hydrogel-based dressings, emphasizing state-of-the-art technologies used this purpose trend achieving personalized therapeutic approaches. Despite promising vitro vivo findings described review, further clinical validation large-scale manufacturing optimizations required widespread adoption.

Language: Английский

Citations

3
The synergistic effect of 1-butyl-3-methylimidazolium chloride and glycerol on the performance of chitosan films DOI
Ning Li, Chang Liu, Li Niu

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 140456 - 140456

Published: Jan. 1, 2025

Language: Английский

Citations

0
Preparation and characterization of a novel oligomeric gum from Eucommia ulmoides crosslinked with carboxymethyl chitosan antibacterial wound dressing for quick hemostasis DOI

Yi‐Chun Yang,

Zemin Ou, Zhimin Wang

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 142652 - 142652

Published: March 1, 2025

Language: Английский

Citations

0
State-of-the-art in natural hydrogel-based wound dressings: Design, functionalization, and fabrication approaches DOI Creative Commons
Hossein Baniasadi

Advances in Colloid and Interface Science, Journal Year: 2025, Volume and Issue: 342, P. 103527 - 103527

Published: April 25, 2025

Language: Английский

Citations

0
Evaluation on Effects of Chitosan Derived From Shrimp Shells on Engineering Properties, Antioxidant, Antibacterial, and Microstructural Characteristics of Chitosan–Alginate–Carrageenan‐Based Hydrogels DOI
Nguyen Van Phuc, Hoc Thang Nguyen,

Tran Le Anh Khoa

et al.

Journal of Applied Polymer Science, Journal Year: 2025, Volume and Issue: unknown

Published: May 6, 2025

ABSTRACT This study aimed to evaluate the effects of chitosan, extracted from shrimp shells, on engineering, antioxidant, antibacterial, and microstructural properties chitosan–alginate–carrageenan‐based hydrogels. Hydrogels were synthesized with fixed sodium alginate (1.00 g) carrageenan (0.50 while varying chitosan content 0.50 1.50 g (samples M1, M2, M3, M4, M5). Among samples, M3 chitosan) demonstrated optimal performance a tensile strength 5.3 MPa, swelling ratio 1202% (at pH 7) 1256% 11), lowest conductivity (306.2 μS/cm). sample also exhibited highest scavenging activity (94.95%) after 120 h maximum antibacterial efficiency (99.2% against E. coli , 99.0% S. aureus ). Structural characterization revealed that had an amorphous structure confirmed by X‐ray diffraction (XRD), highly porous microstructure (micron‐sized pores) observed via scanning electron microscopy (SEM), facilitating water absorption molecular diffusion. Analysis Fourier transform infrared spectroscopy (FTIR) indicated strong intermolecular interactions through ionic bonds hydrogen bonding among OH, NH, CO, COO − OSO 3 COC groups. These findings highlight potential chitosan‐based natural hydrogels for biomedical, food packaging, environmental applications.

Language: Английский

Citations

0
Nanoformulations Loaded with Phytochemicals for Combating Wound Infections and Promoting Wound Healing: Current Applications and Innovations DOI Creative Commons
Panoraia I. Siafaka, Αndroulla N. Miliotou, Mehmet Evren Okur

et al.

Applied Sciences, Journal Year: 2025, Volume and Issue: 15(10), P. 5413 - 5413

Published: May 12, 2025

Wounds are broadly classified into acute and chronic types, with wounds being those that cannot heal within 4 to 12 weeks despite treatment. There is a growing interest in efficient cost-effective wound healing though the drug delivery of active molecules. Natural compounds such as phytochemicals, well synthetic molecules antimicrobial or anti-inflammatory growth factors, can impact tissue regeneration prevent infections. Nanotechnology-based systems, polymeric inorganic nanoparticles electrospun nanofibrous matrices loaded enhance therapeutic efficacy through improved bioavailability targeted delivery. This review summarizes most current advanced applications combining phytochemicals nanoformulations promising potential. Various nanosystems have been identified, silver nanocarriers, zein-based nanoparticles, various known polymers, which be utilized develop fibrous structures phytoremedies. Despite incorporation these remedies traditional medicine for long time, further clinical studies essential determine their pharmacological properties, safety concerns, efficacy.

Language: Английский

Citations

0