Advancing Antidepressive Agents: Drug Discovery and Polymer-Based Drug Delivery Systems for Improved Treatment Outcome DOI Creative Commons
Yufei Zhang, Zhiguang Song, Hongxi Zhang

et al.

Biomedicines, Journal Year: 2025, Volume and Issue: 13(5), P. 1081 - 1081

Published: April 29, 2025

Depressive disorder (a subclass of mental disorders) is characterized by persistent affective symptoms. Without timely therapeutic intervention, it leads to clinical deterioration manifested as reduced quality life and may increase suicide risk in severe cases. Given its complex etiology, intertwined with intrinsic factors such genetics environment, impacted various issues first-pass effect blood-brain barrier, the efficacy many antidepressant medications limited for patients. Therefore, delving into exploration novel drugs biomaterials, this review aims offer fresh perspectives that facilitate discovery innovative enhance their outcomes. Notably, highlights polymers’ crucial role enhancing antidepressants’ pharmacological pharmacokinetic properties optimizing parameters, they will undoubtedly become powerful tools improving antidepressive outcomes future research.

Language: Английский

Advancing Antidepressive Agents: Drug Discovery and Polymer-Based Drug Delivery Systems for Improved Treatment Outcome DOI Creative Commons
Yufei Zhang, Zhiguang Song, Hongxi Zhang

et al.

Biomedicines, Journal Year: 2025, Volume and Issue: 13(5), P. 1081 - 1081

Published: April 29, 2025

Depressive disorder (a subclass of mental disorders) is characterized by persistent affective symptoms. Without timely therapeutic intervention, it leads to clinical deterioration manifested as reduced quality life and may increase suicide risk in severe cases. Given its complex etiology, intertwined with intrinsic factors such genetics environment, impacted various issues first-pass effect blood-brain barrier, the efficacy many antidepressant medications limited for patients. Therefore, delving into exploration novel drugs biomaterials, this review aims offer fresh perspectives that facilitate discovery innovative enhance their outcomes. Notably, highlights polymers’ crucial role enhancing antidepressants’ pharmacological pharmacokinetic properties optimizing parameters, they will undoubtedly become powerful tools improving antidepressive outcomes future research.

Language: Английский

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