Mustansiriya Medical Journal, Journal Year: 2024, Volume and Issue: unknown
Published: Sept. 13, 2024
Language: Английский
Frontiers in Public Health, Journal Year: 2025, Volume and Issue: 12
Published: Jan. 21, 2025
Objectives This study aims to analyze the global burden of otitis media and predict future trends using data from Global Burden Disease 2021 (GBD 2021). Study design A cross-sectional analysis GBD results was conducted. Methods Age-standardized incidence rates (ASIR), age-standardized prevalence (ASPR), disability-adjusted life years (DALYs) (ASDR) were calculated. Trend conducted estimated annual percentage change (EAPC), Joinpoint regression, age-period-cohort, decomposition analyses. Future projections generated Bayesian age-period-cohort (BAPC) auto-regressive integrated moving average (ARIMA) models. Results The rose 322.1 million cases in 1992 391.3 2021, with ASIR increasing slightly 5345.09 5529.1 per 100,000 (EAPC: 0.11%). Despite this increase, ASPR decreased 1786.56 1593.74 -0.43%). DALYs increased 2.16 2.48 million; however, ASDR declined 37.68 32.54 −0.51%). Notably, low low-middle SDI regions showed significant disparities, higher ASIRs (up 5315.08 for males) but declining ASPR. Regionally, East Asia exhibited most substantial decline (−1.14%) (−1.22%), while Central Sub-Saharan Africa demonstrated stable ASDR. indicate a rising through 2036. Conclusion shows regional rate. Public health interventions have been effective regions, targeted efforts are needed further reduce media.
Language: Английский
Citations
1
Children, Journal Year: 2025, Volume and Issue: 12(5), P. 591 - 591
Published: April 30, 2025
Background and Aim: Probiotics, prebiotics, synbiotics have been documented to modulate the microbiota, enhance immunity, reduce antibiotic resistance, making them a promising alternative in management of acute otitis media (AOM). Accordingly, aim this study was determine their effectiveness prevention treatment AOM patients. Methods: A systematic review meta-analysis randomized controlled trials published between 2000 2024 conducted using Science Direct, PubMed, LILACS, SCOPUS, Web Science, Cochrane Clinical Trials, following PRISMA guidelines. The methodological quality evaluated Jadad scale, performed with RevMan 5.4® Jamovi 2.3.28®. Results: total 16 4034 patients were included. showed that intervention did not affect time presentation (MD: −7.98; 95% CI: −19.74 3.78; p = 0.18), recurrence disease (RR: 0.99; 0.74–1.33; 0.96), or requirement for antibiotics 1.31; 0.92 1.84; 0.13); however, it associated reduced probability developing 0.80; 0.66 0.96; 0.02). Subgroup analysis suggests effect probiotic supplementation on incidence is influenced by duration, patient age, number strains product. Conclusions: Supplementation probiotics, significant reduction children, although no impact observed other key clinical parameters. These interventions may be considered as complementary strategy conventional treatments; further high-quality, standardized are needed confirm these findings define optimal protocols.
Language: Английский
Citations
0
Journal of Clinical Medicine, Journal Year: 2024, Volume and Issue: 13(9), P. 2606 - 2606
Published: April 29, 2024
Background/Objectives: Cholesteatoma presents significant management challenges in otolaryngology. This study aimed to delineate the influence of demographic and clinical characteristics, preoperative imaging, surgical approaches on treatment success cholesteatoma management. Methods: A cross-sectional analytical was conducted at Otolaryngology Department University Hospital from January 2021 December 2022. It included 68 patients diagnosed with cholesteatoma, focusing three objectives: assessing impact characteristics outcomes, evaluating predictive value imaging findings, analyzing factors. Results: The population predominantly consisted male (56%) Saudi (81%) patients, an average age 45 years. Logistic regression revealed that older (OR: 1.05), gender 0.63), non-Saudi Arab ethnicity 2.14) significantly impacted outcomes. Clinical such as severe disease severity 3.00) longer symptom duration 0.96) also influenced success. In labyrinthine fistula (Regression Coefficient: 0.63) epidural extension (Coefficient: 0.55) emerged key predictors. factors affected outcomes extent surgery (Complete Removal OR: 3.32) use endoscopic 1.42). Conclusions: highlights patient demographics, profiles, specific features, strategies multifactorially determine These findings suggest necessity for a tailored approach management, reinforcing importance individualized plans based comprehensive assessments.
Language: Английский
Citations
3
Pediatric Infectious Disease, Journal Year: 2024, Volume and Issue: 6(2), P. 40 - 48
Published: May 15, 2024
IntroductIon][4] The prevalence and overall burden of AOM varies geographically, data from India are limited sporadic. 5][8] Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis viruses such as a respiratory syncytial virus, influenza adenovirus the central pathogens in etiology OME. 9 Pneumatic otoscopy is gold standard for diagnosing AOM. 10 Hallmark otoscopic features symptomatic children include recent otalgia, bulging tympanic membrane (TM), erythema TM, mobility, new-onset ear drainage. 10By contrast, OME characterized by presence fluid middle space without signs acute inflammation commonly diagnosed with combined use otoscopy, pneumatic tympanometry.Management options covers therapy (paracetamol or ibuprofen), watchful waiting, antibiotic
Language: Английский
Citations
0
Mustansiriya Medical Journal, Journal Year: 2024, Volume and Issue: unknown
Published: Sept. 13, 2024
Language: Английский
Citations
0