A One Health Zoonotic Vector Borne Infectious Disease Family Outbreak Investigation DOI Creative Commons
Edward B. Breitschwerdt, Ricardo G. Maggi, Charlotte O. Moore

et al.

Pathogens, Journal Year: 2025, Volume and Issue: 14(2), P. 110 - 110

Published: Jan. 23, 2025

This study reinforces the value of a One Health approach to infectious disease outbreak investigations. After onset neuropsychiatric symptoms in their son, our investigation focused on family composed mother, father, two daughters, dogs, and rabbit, all with exposures vectors (fleas ticks), rescued other animals. Between 2020 2022, members experienced illnesses that included neurological symptoms. Prolonged menorrhagia (130d) youngest daughter ultimately resolved following antibiotic administration. dog was diagnosed splenic hematoma months later spinal histiocytic sarcoma. The both one were seroreactive multiple Bartonella spp. antigens, whereas mother son not seroreactive. quintana DNA amplified from specimens obtained members. Based upon sequencing, infection B. confirmed for pet dogs. henselae sequenced daughter, (co-infected quintana), Ctenocephalides felis collected rabbit. All five infected Babesia divergens-like MO-1. Both parents co-infected microti. Droplet digital PCR supported potential Borrelia species three provided additional case-based evidence supporting role stealth Babesia, Bartonella, pathogens as cause or cofactor We conclude approach, particularly vector borne such spp., will enhance clinical epidemiological understanding these organisms animal human health. During investigations it is critical document travel exposure histories, symptoms, pathology pets patients, contact rescued, wild, feral animals perform diagnostic testing includes members, pets, vectors.

Language: Английский

A One Health Zoonotic Vector Borne Infectious Disease Family Outbreak Investigation DOI Creative Commons
Edward B. Breitschwerdt, Ricardo G. Maggi, Charlotte O. Moore

et al.

Pathogens, Journal Year: 2025, Volume and Issue: 14(2), P. 110 - 110

Published: Jan. 23, 2025

This study reinforces the value of a One Health approach to infectious disease outbreak investigations. After onset neuropsychiatric symptoms in their son, our investigation focused on family composed mother, father, two daughters, dogs, and rabbit, all with exposures vectors (fleas ticks), rescued other animals. Between 2020 2022, members experienced illnesses that included neurological symptoms. Prolonged menorrhagia (130d) youngest daughter ultimately resolved following antibiotic administration. dog was diagnosed splenic hematoma months later spinal histiocytic sarcoma. The both one were seroreactive multiple Bartonella spp. antigens, whereas mother son not seroreactive. quintana DNA amplified from specimens obtained members. Based upon sequencing, infection B. confirmed for pet dogs. henselae sequenced daughter, (co-infected quintana), Ctenocephalides felis collected rabbit. All five infected Babesia divergens-like MO-1. Both parents co-infected microti. Droplet digital PCR supported potential Borrelia species three provided additional case-based evidence supporting role stealth Babesia, Bartonella, pathogens as cause or cofactor We conclude approach, particularly vector borne such spp., will enhance clinical epidemiological understanding these organisms animal human health. During investigations it is critical document travel exposure histories, symptoms, pathology pets patients, contact rescued, wild, feral animals perform diagnostic testing includes members, pets, vectors.

Language: Английский

Citations

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