Synthesis, characterization, electronic properties, and cytotoxic activities on cancer cells line of novel Cu(II) complexes with benzimidazole-Schiff base tridentate ligand DOI
Wesley Vieira Ferreira,

Fátima R. Ráice,

Alecia F. da Silva

et al.

Journal of Molecular Structure, Journal Year: 2024, Volume and Issue: unknown, P. 141239 - 141239

Published: Dec. 1, 2024

Language: Английский

Antitumor activity of ruthenium(III) complexes with [N2O2]-tetradentate Schiff base ligands DOI

Zdravka Petrova,

Teodora Mocanu,

Rossen Spasov

et al.

Journal of Inorganic Biochemistry, Journal Year: 2025, Volume and Issue: unknown, P. 112853 - 112853

Published: Feb. 1, 2025

Language: Английский

Citations

0
Structural Elucidation and Computational Studies of Novel Bidentate Organometallic Complexes of 2-Thiophene Carboxylic Acid with Ethyl-2-Amino Acetate for Antidiabetic Applications DOI

R. Vijayakumar,

R. Tamilarasan, K. Jayamoorthy

et al.

Journal of Molecular Structure, Journal Year: 2025, Volume and Issue: unknown, P. 141829 - 141829

Published: Feb. 1, 2025

Language: Английский

Citations

0
Multifunctional Bioactivity of the [Cu(en)(Im)2](ClO4)2 Complex: Antimicrobial, Antibiofilm, and Anticancer Effects DOI Creative Commons

K. G. Parthiban,

Ganeshraja Ayyakannu Sundaram,

Dhanraj Ganapathy

et al.

The Microbe, Journal Year: 2025, Volume and Issue: unknown, P. 100307 - 100307

Published: March 1, 2025

Language: Английский

Citations

0
808 nm Light-Triggered Cyanine-Decorated Iridium(III) Complexes for Antibacterial Photodynamic Therapy in Deep-Tissue DOI

Baraka Joseph Butuyuyu,

Jiqiang Liu, Qihang Ding

et al.

Inorganic Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: April 11, 2025

Acute bacterial skin and structure infections (ABSSSIs) pose significant global health challenges, exacerbated by rising antibiotic resistance. Antibacterial photodynamic therapy (APDT) has emerged as a promising strategy to combat these utilizing photosensitizer (PS) that generates reactive oxygen species (ROS) upon light activation. However, the limited tissue penetration of conventional organic PSs, which primarily absorb in UV-vis spectra, hindered their therapeutic potential for deeper infections. Herein, we introduce novel iridium(III)-cyanine complex (Ir-cy) with strong near-infrared (NIR) absorption at 814 nm (up 101 red-shifted from previous reports), specifically designed enhance APDT. Under 808 laser irradiation, Ir-cy demonstrated substantial ROS generation capacity, achieving approximately 70% reduction Staphylococcus aureus (S. aureus) colonies depth 7.2 mm within simulated model. Comprehensive vitro vivo evaluations further confirmed its potent antibacterial efficacy against S. while maintaining excellent biocompatibility. These findings highlight highly effective NIR-active PS, paving way advanced strategies targeting deep-tissue ABSSSIs through optimized

Language: Английский

Citations

0
Exploring Mesophase Behavior and Biological Potential of Trifluoromethoxy Substituted Schiff Base-Vanilloxyl Liquid Crystals: Experimental and Computational Studies DOI

Palkesh N. Chauhan,

Paresh Solanki,

Vipul C. Kotadiya

et al.

Published: Jan. 1, 2024

Language: Английский

Citations

0
Synthesis, characterization, electronic properties, and cytotoxic activities on cancer cells line of novel Cu(II) complexes with benzimidazole-Schiff base tridentate ligand DOI
Wesley Vieira Ferreira,

Fátima R. Ráice,

Alecia F. da Silva

et al.

Journal of Molecular Structure, Journal Year: 2024, Volume and Issue: unknown, P. 141239 - 141239

Published: Dec. 1, 2024

Language: Английский

Citations

0